Reds vs Nationals Prediction, Odds, Moneyline, Spread & Over/Under for May 4

Odds updated as of 4:17 a.m.

The Cincinnati Reds versus the Washington Nationals is on the MLB schedule for Sunday.

Before you do any MLB betting on this matchup at FanDuel Sportsbook, here's what you need to know.

Reds vs Nationals Game Info

• Cincinnati Reds (18-16) vs. Washington Nationals (15-19)
• Date: Sunday, May 4, 2025
• Time: 4:10 p.m. ET
• Venue: Great American Ball Park -- Cincinnati, Ohio
• Coverage: FDSOH and MASN2

Reds vs Nationals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CIN: (-116) | WSH: (-102)
• Spread: CIN: +1.5 (-192) | WSH: -1.5 (+158)
• Total: 8.5 -- Over: (-106) | Under: (-114)

Reds vs Nationals Probable Starting Pitchers

Probable Pitchers: Nicholas Martínez (Reds) - 1-3, 4.68 ERA vs MacKenzie Gore (Nationals) - 2-3, 3.51 ERA

The Reds will give the ball to Nicholas Martinez (1-3, 4.68 ERA), who is eyeing win No. 2 on the season, and the Nationals will counter with MacKenzie Gore (2-3, 3.51 ERA). Martinez and his team are 2-4-0 ATS this season when he starts. Martinez's team is 1-1 this season when he starts and they're favored on the moneyline. When Gore starts, the Nationals are 3-4-0 against the spread. The Nationals have been the underdog on the moneyline in three of Gore's starts this season, and they went 1-2 in those games.

Reds vs Nationals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Reds win (58.6%)

Reds vs Nationals Moneyline

• Washington is the underdog, -102 on the moneyline, while Cincinnati is a -116 favorite at home.

Reds vs Nationals Spread

• The Nationals are 1.5-run favorites against the spread for this matchup with the Reds. The Nationals are +158 to cover, while the Reds are -192 to cover as a 1.5-run underdog on the runline.

Reds vs Nationals Over/Under

• Reds versus Nationals, on May 4, has an over/under of 8.5, with the over being -106 and the under -114.

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Reds vs Nationals Betting Trends

• The Reds have won in nine, or 56.2%, of the 16 contests they have been named as odds-on favorites in this year.
• This season Cincinnati has been victorious eight times in 15 chances when named as a favorite of at least -116 on the moneyline.
• The Reds and their opponents have gone over the total this season in 16 of their 33 opportunities.
• The Reds are 18-15-0 against the spread in their 33 games with a line set by sportsbooks this season.
• The Nationals have won 13 of the 26 games they were listed as the moneyline underdog this season (50%).
• Washington has a record of 12-12 when it has played as a moneyline underdog with odds of -102 or longer (50%).
• The Nationals have combined with opponents to hit the over on the total 17 times this season for a 17-15-0 record against the over/under.
• The Nationals have collected an 18-14-0 record ATS this season (covering 56.2% of the time).

Reds Player Leaders

• Elly De La Cruz has an OPS of .783, fueled by an OBP of .356 and a team-best slugging percentage of .427 this season. He has a .275 batting average.
• He ranks 44th in batting average, 46th in on-base percentage, and 69th in slugging among all qualified batters in baseball.
• TJ Friedl has an OPS of .680, fueled by an OBP of .327 and a team-best slugging percentage of .353 this season. He's batting .271.
• His batting average is 54th among qualified players, his on-base percentage 75th, and his slugging percentage 120th.
• Friedl brings a three-game streak with at least one hit into this one. During his last five outings he is hitting .190 with a walk and an RBI.
• Gavin Lux leads Cincinnati with 33 hits and an OBP of .402 this season.
• Noelvi Marte has been key for Cincinnati with 19 hits, an OBP of .348 plus a slugging percentage of .531.

Nationals Player Leaders

• James Wood has a team-best OBP (.384) and slugging percentage (.547), and paces the Nationals in hits (35, while batting .273).
• Including all qualified hitters in MLB, he is 50th in batting average, 23rd in on-base percentage and 17th in slugging percentage.
• Wood hopes to build on a three-game hitting streak in this matchup. During his last five outings he is batting .368 with two doubles, five walks and an RBI.
• Nathaniel Lowe has six doubles, six home runs and 14 walks while batting .252. He's slugging .441 with an on-base percentage of .326.
• Including all qualified players, his batting average places him 77th, his on-base percentage ranks 76th, and he is 61st in slugging.
• Keibert Ruiz is batting .291 with four doubles, two home runs and seven walks.
• Luis Garcia is hitting .231 with five doubles, two home runs and eight walks.

Reds vs Nationals Head to Head

• 5/3/2025: 11-6 WSH (Favorite: Reds, Spread: -1.5, Total: 9, Favorite Moneyline: -196, Underdog Moneyline: +164)
• 7/21/2024: 5-2 WSH (Favorite: Nationals, Spread: -1.5, Total: 9.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 7/20/2024: 5-4 WSH (Favorite: Reds, Spread: -1.5, Total: 8, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 7/19/2024: 8-5 WSH (Favorite: Reds, Spread: -1.5, Total: 9.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 3/31/2024: 6-5 CIN (Favorite: Reds, Spread: -1.5, Total: 9.5, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 3/30/2024: 7-6 WSH (Favorite: Reds, Spread: -1.5, Total: 10.5, Favorite Moneyline: -184, Underdog Moneyline: +154)
• 3/28/2024: 8-2 CIN (Favorite: Reds, Spread: -1.5, Total: 9.5, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 8/6/2023: 6-3 WSH (Favorite: Reds, Spread: -1.5, Total: 10.5, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 8/5/2023: 7-3 WSH (Favorite: Reds, Spread: -1.5, Total: 10.5, Favorite Moneyline: -235, Underdog Moneyline: +194)
• 8/4/2023: 6-3 WSH (Favorite: Reds, Spread: -1.5, Total: 10.5, Favorite Moneyline: -184, Underdog Moneyline: +154)

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