Pirates vs Astros Prediction, Odds, Moneyline, Spread & Over/Under for June 3

Odds updated as of 7:12 a.m.

The Pittsburgh Pirates versus the Houston Astros is on the MLB schedule for Wednesday.

All the information you need to make smart bets on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Pirates vs Astros Game Info

• Pittsburgh Pirates (33-28) vs. Houston Astros (27-35)
• Date: Wednesday, June 3, 2026
• Time: 8:10 p.m. ET
• Venue: Daikin Park -- Houston, Texas
• Coverage: SCHN and SportsNet PT

Pirates vs Astros Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: PIT: (-164) | HOU: (+138)
• Spread: PIT: -1.5 (+104) | HOU: +1.5 (-125)
• Total: 7.5 -- Over: (-122) | Under: (+100)

Pirates vs Astros Probable Starting Pitchers

Probable Pitchers: Paul Skenes (Pirates) - 6-5, 2.89 ERA vs Spencer Arrighetti (Astros) - 7-1, 1.34 ERA

This contest's pitching matchup is set, as the Pirates will send Paul Skenes (6-5) to the mound, while Spencer Arrighetti (7-1) will get the nod for the Astros. Skenes' team is 5-7-0 against the spread this season in his starts. Skenes' team is 6-5 this season when he starts and they are the moneyline favorite. The Astros have a 7-1-0 ATS record in Arrighetti's eight starts that had a set spread. The Astros are 6-1 in Arrighetti's seven starts this season that they were the underdog on the moneyline.

Pirates vs Astros Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Pirates win (59.6%)

Pirates vs Astros Moneyline

• Pittsburgh is the favorite, -164 on the moneyline, while Houston is a +138 underdog despite being at home.

Pirates vs Astros Spread

• The Astros are +1.5 on the run line against the Pirates. The Astros are -125 to cover, and the Pirates are +104.

Pirates vs Astros Over/Under

• Pirates versus Astros on June 3 has an over/under of 7.5 runs, with the odds on the over -122 and the under set at +100.

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Pirates vs Astros Betting Trends

• The Pirates have been victorious in 22, or 61.1%, of the 36 contests they have been chosen as favorites in this season.
• This season Pittsburgh has come away with a win five times in nine chances when named as a favorite of at least -164 on the moneyline.
• The Pirates and their opponents have hit the over in 33 of their 60 games with a total set by oddsmakers this season.
• The Pirates have an against the spread record of 30-30-0 in 60 games with a line this season.
• The Astros have won 47.7% of the games this season they were the moneyline underdog (21-23).
• Houston is 3-6 (winning just 33.3% of its games) when it has played as a moneyline underdog of +138 or longer.
• The Astros have played in 62 games with a set over/under, and have combined with their opponents to go over the total 34 times (34-26-2).
• The Astros have a 28-34-0 record against the spread this season (covering 45.2% of the time).

Pirates Player Leaders

• Bryan Reynolds leads Pittsburgh with an OBP of .403 this season while batting .272 with 44 walks and 39 runs scored. He has a slugging percentage of .432.
• Among all qualifying batters in MLB, his batting average ranks 51st, his on-base percentage ranks sixth, and he is 67th in slugging.
• Brandon Lowe has 55 hits, which is tops among Pittsburgh batters this season. He's batting .258 with 28 extra-base hits. He's also slugging .535 with an on-base percentage of .343.
• Among qualified hitters, his batting average places him 66th, his on-base percentage 64th, and his slugging percentage ninth.
• Lowe brings a three-game streak with at least one hit into this matchup. In his last five games he is batting .150 with a home run, a walk and four RBIs.
• Oneil Cruz has 62 hits this season and has a slash line of .258/.331/.475.
• Spencer Horwitz has been key for Pittsburgh with 50 hits, an OBP of .385 plus a slugging percentage of .458.

Astros Player Leaders

• Yordan Alvarez has racked up an on-base percentage of .419, a slugging percentage of .645, and has 67 hits, all club-bests for the Astros (while batting .305).
• Including all qualifying hitters in MLB, he ranks 12th in batting average, second in on-base percentage and second in slugging percentage.
• Christian Walker is batting .248 with 10 doubles, 16 home runs and 21 walks. He's slugging .504 with an on-base percentage of .321.
• Including all qualifying hitters, his batting average puts him 86th, his on-base percentage is 98th, and he is 26th in slugging.
• Isaac Paredes is batting .233 with 10 doubles, six home runs and 21 walks.
• Cam Smith is batting .216 with eight doubles, six home runs and 24 walks.

Pirates vs Astros Head to Head

• 6/2/2026: 10-6 PIT (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 6/4/2025: 3-0 PIT (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 6/3/2025: 3-0 HOU (Favorite: Pirates, Spread: -1.5, Total: 7, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 7/31/2024: 5-4 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -225, Underdog Moneyline: +188)
• 7/30/2024: 6-2 PIT (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -198, Underdog Moneyline: +166)
• 7/29/2024: 5-3 PIT (Favorite: Pirates, Spread: -1.5, Total: 7.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 4/12/2023: 7-0 HOU (Favorite: Astros, Spread: -1.5, Total: 9.5, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 4/11/2023: 7-4 PIT (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 4/10/2023: 8-2 HOU (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -188, Underdog Moneyline: +158)

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