Phillies vs White Sox Prediction, Odds, Moneyline, Spread & Over/Under for June 6

Odds updated as of 1:12 a.m.

The Saturday slate in MLB includes a matchup between the Philadelphia Phillies and the Chicago White Sox.

We've got you covered, in terms of the most important info regarding this game before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Phillies vs White Sox Game Info

• Philadelphia Phillies (34-29) vs. Chicago White Sox (33-30)
• Date: Saturday, June 6, 2026
• Time: 4:05 p.m. ET
• Venue: Citizens Bank Park -- Philadelphia, Pennsylvania
• Coverage: NBCS-PH and CHSN

Phillies vs White Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: PHI: (-136) | CHW: (+116)
• Spread: PHI: -1.5 (+136) | CHW: +1.5 (-164)
• Total: 9.5 -- Over: (-120) | Under: (-102)

Phillies vs White Sox Probable Starting Pitchers

Probable Pitchers: Andrew Painter (Phillies) - 1-6, 5.74 ERA vs Brandon Eisert (White Sox) - 1-0, 3.55 ERA

The Phillies will call on Andrew Painter (1-6) versus the White Sox and Brandon Eisert (1-0). Painter and his team have a record of 1-9-0 against the spread when he starts. Painter's team is 3-1 this season when he starts and they are the moneyline favorite. Eisert has started only one game with a set spread, which the White Sox covered. The White Sox have not been a moneyline underdog when Eisert starts this season.

Phillies vs White Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Phillies win (50.6%)

Phillies vs White Sox Moneyline

• Philadelphia is the favorite, -136 on the moneyline, while Chicago is a +116 underdog on the road.

Phillies vs White Sox Spread

• The Phillies are hosting the White Sox and are favored by 1.5 runs on the spread. The Phillies are +136 to cover the runline, with the White Sox being -164.

Phillies vs White Sox Over/Under

• Phillies versus White Sox, on June 6, has an over/under of 9.5, with the over being -120 and the under -102.

Bet on Philadelphia Phillies vs. Chicago White Sox on FanDuel today!

Phillies vs White Sox Betting Trends

• The Phillies have won in 26, or 60.5%, of the 43 contests they have been named as odds-on favorites in this year.
• Philadelphia has a record of 21-13 in contests when oddsmakers favor them by -136 or more on the moneyline.
• The Phillies and their opponents have gone over the total this season in 27 of their 62 opportunities.
• The Phillies are 20-42-0 against the spread in their 62 games that had a posted line this season.
• The White Sox have been the underdog on the moneyline 50 total times this season. They've finished 24-26 in those games.
• When it has played as a moneyline underdog with odds of +116 or longer, Chicago has a 15-18 record (winning 45.5% of its games).
• The White Sox have had an over/under set by oddsmakers 61 times, and have combined with opponents to go over the total in 35 of those games (35-25-1).
• The White Sox have covered 57.4% of their games this season, going 35-26-0 against the spread.

Phillies Player Leaders

• Bryce Harper leads Philadelphia with an OBP of .369 this season while batting .265 with 38 walks and 38 runs scored. He has a slugging percentage of .511.
• Among all qualifying hitters in MLB, his batting average ranks 57th, his on-base percentage ranks 29th, and he is 25th in slugging.
• Harper will look for his third straight game with a hit in this contest. In his last five games he is batting .286 with a home run, five walks and two RBIs.
• Kyle Schwarber leads Philadelphia in total hits (56) this season while batting .246 with 33 extra-base hits. He's slugging .596 with an on-base percentage of .361.
• Among qualifying batters, he is 94th in batting average, 37th in on-base percentage and third in slugging percentage.
• Schwarber enters this game looking to extend his three-game hit streak. During his last five outings he is batting .333 with a home run, five walks and an RBI.
• Brandon Marsh has an OPS of .849, fueled by an OBP of .361 and a team-best slugging percentage of .488 this season.
• Marsh has recorded a hit in four straight games. During his last five outings he is hitting .421 with a home run, a walk and three RBIs.
• Trea Turner has seven home runs, 21 RBI and a batting average of .224 this season.

White Sox Player Leaders

• Miguel Vargas is hitting .243 with 10 doubles, a triple, 15 home runs and 42 walks. He's slugging .500 with an on-base percentage of .373.
• He is 98th in batting average, 26th in on-base percentage and 28th in slugging percentage among all qualifying hitters in MLB.
• Vargas brings a four-game hitting streak into this matchup. During his last five outings he is hitting .316 with a double, two home runs, four walks and seven RBIs.
• Colson Montgomery is batting .223 with 11 doubles, 15 home runs and 22 walks. He's slugging .467 with an on-base percentage of .315.
• Including all qualifying hitters, his batting average puts him 130th, his on-base percentage ranks 111th, and he is 41st in slugging.
• Chase Meidroth has put up a slugging percentage of .393, a team-best for the White Sox.
• Sam Antonacci is hitting .286 with eight doubles, two triples, a home run and 11 walks.

Phillies vs White Sox Head to Head

• 6/5/2026: 8-6 PHI (Favorite: Phillies, Spread: -1.5, Total: 8.5, Favorite Moneyline: -190, Underdog Moneyline: +160)
• 7/29/2025: 6-3 PHI (Favorite: Phillies, Spread: -1.5, Total: 9, Favorite Moneyline: -178, Underdog Moneyline: +150)
• 7/28/2025: 6-2 CHW (Favorite: Phillies, Spread: -1.5, Total: 8.5, Favorite Moneyline: -240, Underdog Moneyline: +194)
• 4/21/2024: 8-2 PHI (Favorite: Phillies, Spread: -1.5, Total: 7.5, Favorite Moneyline: -290, Underdog Moneyline: +235)
• 4/20/2024: 9-5 PHI (Favorite: Phillies, Spread: -1.5, Total: 7.5, Favorite Moneyline: -375, Underdog Moneyline: +300)
• 4/19/2024: 7-0 PHI (Favorite: Phillies, Spread: -1.5, Total: 7.5, Favorite Moneyline: -184, Underdog Moneyline: +154)
• 4/19/2023: 5-2 PHI (Favorite: Phillies, Spread: -1.5, Total: 8.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 4/18/2023: 3-0 CHW (Favorite: White Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 4/18/2023: 7-4 PHI (Favorite: Phillies, Spread: -1.5, Total: 8, Favorite Moneyline: -130, Underdog Moneyline: +110)

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