Padres vs Twins Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 23

Odds updated as of 10:12 p.m.

MLB action on Sunday includes the San Diego Padres taking on the Minnesota Twins.

Before you do any MLB betting on this matchup at FanDuel Sportsbook, here's everything you need to know.

Padres vs Twins Game Info

• San Diego Padres (69-60) vs. Minnesota Twins (63-66)
• Date: Sunday, August 23, 2026
• Time: 4:10 p.m. ET
• Venue: Petco Park -- San Diego, California
• Coverage: Padres.TV and Twins.TV

Padres vs Twins Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SD: (-134) | MIN: (+116)
• Spread: SD: -1.5 (+146) | MIN: +1.5 (-176)
• Total: 8.5 -- Over: (-115) | Under: (-105)

Padres vs Twins Probable Starting Pitchers

Probable Pitchers: Walker Buehler (Padres) - 7-6, 4.79 ERA vs Bailey Ober (Twins) - 7-4, 4.62 ERA

The Padres will give the ball to Walker Buehler (7-6, 4.79 ERA), who is eyeing win No. 8 on the season, and the Twins will counter with Bailey Ober (7-4, 4.62 ERA). Buehler and his team have a record of 18-7-0 against the spread when he starts. Buehler's team is 6-3 this season when he starts and they are the moneyline favorite. The Twins have an 11-7-0 record against the spread in Ober's starts. The Twins are 8-4 in Ober's 12 starts this season that they were the moneyline underdog.

Padres vs Twins Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Padres win (59%)

Padres vs Twins Moneyline

• Looking at the moneyline for Twins-Padres, Minnesota is the underdog at +116, and San Diego is -134 playing at home.

Padres vs Twins Spread

• The Padres are favored by 1.5 runs at home against the Twins. The Padres are +146 to cover the spread, while the Twins are -176.

Padres vs Twins Over/Under

• The over/under for Padres-Twins on Aug. 23 is 8.5. The over is -115, and the under is -105.

Bet on San Diego Padres vs. Minnesota Twins on FanDuel today!

Padres vs Twins Betting Trends

• The Padres have won in 31, or 56.4%, of the 55 contests they have been named as odds-on favorites in this year.
• This year San Diego has won 16 of 26 games when listed as at least -134 on the moneyline.
• Contests with the Padres have gone over the total set by oddsmakers in 56 of 129 chances this season.
• The Padres have posted a record of 74-55-0 against the spread this season.
• The Twins have gone 36-43 in games they were listed as the moneyline underdog (winning 45.6% of those games).
• In games it has played as a moneyline underdog with odds of +116 or longer, Minnesota has gone 22-24 (47.8%).
• In the 126 games oddsmakers have set an over/under for the Twins, they have combined with opponents to go over the total 69 times (69-54-3).
• The Twins have collected a 69-57-0 record ATS this season.

Padres Player Leaders

• Fernando Tatis Jr. leads San Diego with 140 hits and an OBP of .357, plus a team-best slugging percentage of .438. He's batting .284.
• Among all qualifying hitters in the majors, his batting average ranks 22nd, his on-base percentage ranks 35th, and he is 57th in slugging.
• Tatis has recorded a base hit in three games in a row. In his last five games he is batting .400 with two doubles, two home runs, a walk and six RBIs.
• Manny Machado is hitting .217 with 20 doubles, 24 home runs and 58 walks. He's slugging .414 with an on-base percentage of .301.
• Among qualified batters, his batting average places him 127th, his on-base percentage 116th, and his slugging percentage 82nd.
• Jackson Merrill has 116 hits this season and has a slash line of .238/.288/.405.
• Xander Bogaerts has been key for San Diego with 91 hits, an OBP of .318 plus a slugging percentage of .326.

Twins Player Leaders

• Josh Bell has accumulated a team-best .430 slugging percentage. He's batting .257 with an on-base percentage of .321.
• Including all qualifying hitters in the majors, he ranks 69th in batting average, 85th in on-base percentage and 61st in slugging percentage.
• Brooks Lee has 19 doubles, three triples, 18 home runs and 33 walks while batting .242. He's slugging .416 with an on-base percentage of .297.
• He ranks 96th in batting average, 121st in on-base percentage and 79th in slugging percentage in the big leagues.
• Kody Clemens has put up 98 hits, a team-high for the Twins.
• Luke Keaschall's .363 on-base percentage paces his team.

Padres vs Twins Head to Head

• 8/21/2026: 6-2 SD (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: +108)
• 8/31/2025: 7-2 MIN (Favorite: Twins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 8/30/2025: 12-3 SD (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 8/29/2025: 7-4 MIN (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 8/21/2024: 11-4 MIN (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 8/20/2024: 7-5 SD (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 8/19/2024: 5-3 SD (Favorite: Padres, Spread: -1.5, Total: 7, Favorite Moneyline: -164, Underdog Moneyline: +138)
• 5/11/2023: 5-3 MIN (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 5/10/2023: 4-3 MIN (Favorite: Twins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 5/9/2023: 6-1 SD (Favorite: Twins, Spread: -1.5, Total: 9, Favorite Moneyline: -112, Underdog Moneyline: -104)

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