Padres vs Rockies Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 16

Odds updated as of 4:13 a.m.

On Wednesday in MLB, the San Diego Padres are playing the Colorado Rockies.

All the information you need to make smart wagers on this game at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Padres vs Rockies Game Info

• San Diego Padres (82-69) vs. Colorado Rockies (56-95)
• Date: Wednesday, September 16, 2026
• Time: 8:40 p.m. ET
• Venue: Coors Field -- Denver, Colorado
• Coverage: Rockies.TV and Padres.TV

Padres vs Rockies Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SD: (-166) | COL: (+140)
• Spread: SD: -1.5 (-108) | COL: +1.5 (-111)
• Total: 11.5 -- Over: (+100) | Under: (-122)

Padres vs Rockies Probable Starting Pitchers

Probable Pitchers: Robbie Ray (Padres) - 12-8, 3.57 ERA vs Mason Adams (Rockies) - 0-0, 3.37 ERA

The probable pitchers are Robbie Ray (12-8) for the Padres and Mason Adams for the Rockies. When Ray starts, his team is 16-10-0 against the spread this season. Ray's team is 8-5 this season when he starts and they are the moneyline favorite. The Rockies have gone 3-1-0 ATS in Adams' four starts with a set spread. The Rockies have been the moneyline underdog in four of Adams' starts this season, and they went 2-2 in those matchups.

Padres vs Rockies Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Padres win (61.9%)

Padres vs Rockies Moneyline

• Looking at the moneyline for Padres-Rockies, San Diego is the favorite at -166, and Colorado is +140 playing at home.

Padres vs Rockies Spread

• The Padres are at the Rockies and are favored by 1.5 runs (-108 to cover) on the runline. Colorado is -111 to cover.

Padres vs Rockies Over/Under

• An over/under of 11.5 has been set for Padres-Rockies on Sept. 16, with the over being +100 and the under -122.

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Padres vs Rockies Betting Trends

• The Padres have come away with 43 wins in the 73 contests they have been listed as the favorites in this season.
• This year San Diego has won 11 of 17 games when listed as at least -166 on the moneyline.
• Contests with the Padres have gone over the total set by sportsbooks in 69 of 151 chances this season.
• The Padres have posted a record of 86-65-0 against the spread this season.
• The Rockies have won 36.8% of the games this season they were the moneyline underdog (53-91).
• Colorado is 25-61 (winning just 29.1% of its games) when it has played as a moneyline underdog of +140 or longer.
• The Rockies have played in 148 games with an over/under set, and have combined with their opponents to go over the total 73 times (73-72-3).
• The Rockies are 78-70-0 against the spread this season.

Padres Player Leaders

• Fernando Tatis Jr. leads San Diego in OBP (.356), slugging percentage (.465) and total hits (169) this season. He has a .288 batting average.
• Among all qualified batters in MLB, he ranks 14th in batting average, 37th in on-base percentage, and 36th in slugging.
• Tatis hopes to build on a six-game hitting streak in this matchup. During his last 10 outings he is batting .375 with a triple, four home runs, six walks and eight RBIs.
• Manny Machado is hitting .222 with 22 doubles, 28 home runs and 74 walks, while slugging .416 with an on-base percentage of .312.
• He ranks 126th in batting average, 101st in on-base percentage and 80th in slugging among qualifying hitters.
• Machado brings a three-game streak with at least one hit into this one. In his last five games he is batting .150 with two home runs, three walks and three RBIs.
• Jackson Merrill has 145 hits this season and has a slash line of .253/.302/.441.
• Merrill has recorded a hit in six games in a row. In his last 10 games he is batting .425 with three doubles, a triple, three home runs, two walks and 13 RBIs.
• Xander Bogaerts is batting .223 with a .322 OBP and 54 RBI for San Diego this season.
• Bogaerts enters this matchup on a two-game hitting streak. During his last five outings he is batting .333 with two doubles, a walk and two RBIs.

Rockies Player Leaders

• Jake McCarthy is hitting .297 with 30 doubles, 10 triples, 15 home runs and 28 walks. He's slugging .485 with an on-base percentage of .341.
• Including all qualified hitters, he ranks ninth in batting average, while his on-base percentage is 55th and he is 22nd in slugging.
• TJ Rumfield has a .392 OBP while slugging .455. Both pace his team. He has a batting average of .300.
• Including all qualifying hitters, he is seventh in batting average, fourth in on-base percentage and 43rd in slugging percentage.
• Hunter Goodman has 118 hits, a team-best for the Rockies.
• Kyle Karros has 21 doubles, three triples, 11 home runs and 49 walks while batting .259.

Padres vs Rockies Head to Head

• 9/15/2026: 9-3 COL (Favorite: Padres, Spread: -1.5, Total: 11.5, Favorite Moneyline: -196, Underdog Moneyline: +164)
• 9/14/2026: 8-7 SD (Favorite: Padres, Spread: -1.5, Total: 11.5, Favorite Moneyline: -220, Underdog Moneyline: +184)
• 7/29/2026: 3-1 SD (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -184, Underdog Moneyline: +154)
• 7/28/2026: 8-7 SD (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -230, Underdog Moneyline: +190)
• 4/23/2026: 10-8 SD (Favorite: Padres, Spread: -1.5, Total: 10.5, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 4/22/2026: 8-3 COL (Favorite: Padres, Spread: -1.5, Total: 12, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 4/21/2026: 1-0 SD (Favorite: Padres, Spread: -1.5, Total: 11, Favorite Moneyline: -146, Underdog Moneyline: +124)
• 4/12/2026: 7-2 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -225, Underdog Moneyline: +188)
• 4/11/2026: 9-5 SD (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 4/10/2026: 5-2 SD (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -178, Underdog Moneyline: +150)

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