Mariners vs Angels Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 16

Odds updated as of 4:12 a.m.

The Wednesday slate in MLB includes a matchup between the Seattle Mariners and the Los Angeles Angels.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the most important information about this game.

Mariners vs Angels Game Info

• Seattle Mariners (70-82) vs. Los Angeles Angels (58-93)
• Date: Wednesday, September 16, 2026
• Time: 9:38 p.m. ET
• Venue: Angel Stadium -- Anaheim, California
• Coverage: ABTV and Mariners.TV

Mariners vs Angels Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SEA: (-138) | LAA: (+118)
• Spread: SEA: -1.5 (+125) | LAA: +1.5 (-150)
• Total: 8.5 -- Over: (+104) | Under: (-128)

Mariners vs Angels Probable Starting Pitchers

Probable Pitchers: George Kirby (Mariners) - 9-11, 4.25 ERA vs Yusei Kikuchi (Angels) - 1-5, 4.75 ERA

The probable pitchers are George Kirby (9-11) for the Mariners and Yusei Kikuchi (1-5) for the Angels. When Kirby starts, his team is 9-19-0 against the spread this season. When Kirby starts a game and his team is the favorite on the moneyline, they have a record of 12-13. The Angels have a 4-7-0 record against the spread in Kikuchi's starts. The Angels are 2-6 in Kikuchi's eight starts this season that they were the moneyline underdog.

Mariners vs Angels Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Mariners win (55.5%)

Mariners vs Angels Moneyline

• Seattle is a -138 favorite on the moneyline, while Los Angeles is a +118 underdog at home.

Mariners vs Angels Spread

• The Mariners are favored by 1.5 runs on the road versus the Angels. The Mariners are +125 to cover the spread, while the Angels are -150.

Mariners vs Angels Over/Under

• The over/under for the Mariners versus Angels contest on Sept. 16 has been set at 8.5, with +104 odds on the over and -128 odds on the under.

Bet on Seattle Mariners vs. Los Angeles Angels on FanDuel today!

Mariners vs Angels Betting Trends

• The Mariners have been chosen as favorites in 115 games this year and have walked away with the win 56 times (48.7%) in those games.
• This season Seattle has come away with a win 33 times in 55 chances when named as a favorite of at least -138 on the moneyline.
• The Mariners' games have gone over the total in 80 of their 150 opportunities.
• In 150 games with a line this season, the Mariners have a mark of 55-95-0 against the spread.
• The Angels have been the moneyline underdog 123 total times this season. They've gone 44-79 in those games.
• Los Angeles is 29-52 (winning only 35.8% of its games) when it has played as a moneyline underdog of +118 or longer.
• In the 150 games oddsmakers have set an over/under for the Angels, they have combined with opponents to go over the total 61 times (61-86-3).
• The Angels are 80-70-0 against the spread this season.

Mariners Player Leaders

• Randy Arozarena leads Seattle with an OBP of .373 this season while batting .277 with 61 walks and 100 runs scored. He has a slugging percentage of .477.
• Among all qualified hitters, he is 30th in batting average, his on-base percentage ranks 12th, and he is 26th in slugging.
• Arozarena has picked up at least one hit in five straight games. During his last five outings he is batting .391 with a double, three home runs and eight RBIs.
• Josh Naylor has an OPS of .689, fueled by an OBP of .327 and a team-best slugging percentage of .363 this season. He's batting .271.
• Among all qualifying hitters, he ranks 41st in batting average, 74th in on-base percentage and 123rd in slugging percentage.
• Cole Young has collected 136 base hits, an OBP of .309 and a slugging percentage of .389 this season.
• Julio Rodriguez is batting .241 with a .301 OBP and 66 RBI for Seattle this season.

Angels Player Leaders

• Zach Neto has accumulated 140 hits with a .442 slugging percentage, both team-high stats for the Angels. He's batting .241 and with an on-base percentage of .321.
• Including all the qualified players in MLB, his batting average ranks 97th, his on-base percentage ranks 84th, and he is 56th in slugging.
• Mike Trout leads his team with a .379 on-base percentage. He has a batting average of .243 while slugging .427.
• Including all qualifying hitters, he is 92nd in batting average, ninth in on-base percentage and 67th in slugging percentage.
• Vaughn Grissom is batting .241 with 22 doubles, 11 home runs and 28 walks.
• Wade Meckler has 14 doubles, three home runs and 29 walks while hitting .297.

Mariners vs Angels Head to Head

• 9/15/2026: 2-1 LAA (Favorite: Mariners, Spread: -1.5, Total: 8.5, Favorite Moneyline: -174, Underdog Moneyline: +146)
• 9/14/2026: 6-4 LAA (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 7/2/2026: 1-0 SEA (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -225, Underdog Moneyline: +188)
• 6/30/2026: 8-3 SEA (Favorite: Mariners, Spread: -1.5, Total: 7, Favorite Moneyline: -188, Underdog Moneyline: +158)
• 6/29/2026: 6-2 SEA (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -210, Underdog Moneyline: +176)
• 4/5/2026: 8-7 LAA (Favorite: Mariners, Spread: -1.5, Total: 9, Favorite Moneyline: -164, Underdog Moneyline: +138)
• 4/4/2026: 1-0 LAA (Favorite: Mariners, Spread: -1.5, Total: 9.5, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 4/3/2026: 3-1 SEA (Favorite: Mariners, Spread: -1.5, Total: 8, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 9/14/2025: 11-2 SEA (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -220, Underdog Moneyline: +184)
• 9/13/2025: 5-3 SEA (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -245, Underdog Moneyline: +200)

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