Padres vs Rockies Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 13

Odds updated as of 5:19 a.m.

The San Diego Padres are among the MLB squads busy on Saturday, up against the Colorado Rockies.

Before you do any MLB betting on this matchup at FanDuel Sportsbook, here's everything you need to know.

Padres vs Rockies Game Info

• San Diego Padres (80-68) vs. Colorado Rockies (41-107)
• Date: Saturday, September 13, 2025
• Time: 8:40 p.m. ET
• Venue: PETCO Park -- San Diego, California
• Coverage: SDPA and COLR

Padres vs Rockies Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SD: (-350) | COL: (+280)
• Spread: SD: -1.5 (-182) | COL: +1.5 (+150)
• Total: 8.5 -- Over: (-100) | Under: (-122)

Padres vs Rockies Probable Starting Pitchers

Probable Pitchers: Dylan Cease (Padres) - 7-11, 4.71 ERA vs Bradley Blalock (Rockies) - 0-0, 0.00 ERA

The Padres will give the ball to Dylan Cease (7-11, 4.71 ERA), who is eyeing win No. 8 on the season, and the Rockies will turn to Bradley Blalock. Cease's team is 13-16-0 against the spread this season in his starts. When Cease starts a game and his team is the favorite on the moneyline, they have a record of 13-7. Blalock's team was never a moneyline underdog a season ago in games he pitched.

Padres vs Rockies Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Padres win (69.7%)

Padres vs Rockies Moneyline

• Looking at the moneyline for Rockies-Padres, Colorado is the underdog at +280, and San Diego is -350 playing at home.

Padres vs Rockies Spread

• The Rockies are at +1.5 on the runline against the Padres. The Rockies are +150 to cover the spread, and the Padres are -182.

Padres vs Rockies Over/Under

• An over/under of 8.5 has been set for Padres-Rockies on Sept. 13, with the over being -100 and the under -122.

Bet on San Diego Padres vs. Colorado Rockies on FanDuel today!

Padres vs Rockies Betting Trends

• The Padres have been chosen as favorites in 80 games this year and have walked away with the win 47 times (58.8%) in those games.
• These are the best odds of a victory sportsbooks have given San Diego this season, with a -350 moneyline set for this game.
• The Padres and their opponents have gone over in 62 of their 146 games with a total set by sportsbooks this season.
• The Padres are 78-68-0 against the spread in their 146 games that had a posted line this season.
• The Rockies have been the moneyline underdog 140 total times this season. They've gone 37-103 in those games.
• Colorado is 2-8 (winning just 20% of its games) when it has played as a moneyline underdog of +280 or longer.
• The Rockies have played in 144 games with an over/under set, and have combined with their opponents to go over the total 61 times (61-78-5).
• The Rockies have a 58-86-0 record ATS this season (covering 40.3% of the time).

Padres Player Leaders

• Fernando Tatis Jr. is hitting .259 with 27 doubles, two triples, 21 home runs and 84 walks. He has an on-base percentage of .361 while slugging .429.
• Among all qualified hitters, he ranks 75th in batting average, his on-base percentage ranks 19th, and he is 78th in slugging.
• Manny Machado is batting .274 with 33 doubles, 24 home runs and 52 walks. He's slugging .458 with an on-base percentage of .335.
• He ranks 35th in batting average, 61st in on-base percentage and 49th in slugging in MLB.
• Luis Arraez has an OPS of .706, fueled by an OBP of .320 and a team-best slugging percentage of .386 this season.
• Arraez brings a three-game hitting streak into this game. During his last five outings he is hitting .294 with an RBI.
• Ramon Laureano has 23 home runs, 72 RBI and a batting average of .290 this season.

Rockies Player Leaders

• Hunter Goodman has accumulated a team-high slugging percentage (.532) and paces the Rockies in hits (136). He's batting .279 and with an on-base percentage of .325.
• Including all qualifying players in MLB, he is 25th in batting average, 85th in on-base percentage and 11th in slugging percentage.
• Mickey Moniak is hitting .261 with 17 doubles, eight triples, 19 home runs and 21 walks. He's slugging .491 with an on-base percentage of .300.
• Jordan Beck has put up a team-best .330 on-base percentage.
• Brenton Doyle is hitting .241 with 21 doubles, two triples, 14 home runs and 29 walks.

Padres vs Rockies Head to Head

• 9/12/2025: 4-2 COL (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -270, Underdog Moneyline: +220)
• 9/11/2025: 2-0 SD (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -270, Underdog Moneyline: +220)
• 9/7/2025: 8-1 SD (Favorite: Padres, Spread: -1.5, Total: 11, Favorite Moneyline: -240, Underdog Moneyline: +198)
• 9/6/2025: 10-8 SD (Favorite: Padres, Spread: -1.5, Total: 11.5, Favorite Moneyline: -190, Underdog Moneyline: +160)
• 9/5/2025: 3-0 COL (Favorite: Padres, Spread: -1.5, Total: 10.5, Favorite Moneyline: -220, Underdog Moneyline: +184)
• 5/11/2025: 9-3 COL (Favorite: Padres, Spread: -1.5, Total: 11.5, Favorite Moneyline: -310, Underdog Moneyline: +250)
• 5/10/2025: 21-0 SD (Favorite: Padres, Spread: -1.5, Total: 12, Favorite Moneyline: -240, Underdog Moneyline: +198)
• 5/9/2025: 13-9 SD (Favorite: Padres, Spread: -1.5, Total: 11.5, Favorite Moneyline: -176, Underdog Moneyline: +148)
• 4/13/2025: 6-0 SD (Favorite: Padres, Spread: -1.5, Total: 7, Favorite Moneyline: -245, Underdog Moneyline: +200)
• 4/12/2025: 2-0 SD (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -164, Underdog Moneyline: +138)

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