Padres vs Nationals Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 8

Odds updated as of 6:12 a.m.

The San Diego Padres will face the Washington Nationals in MLB action on Tuesday.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the vital information regarding this game.

Padres vs Nationals Game Info

• San Diego Padres (76-68) vs. Washington Nationals (67-79)
• Date: Tuesday, September 8, 2026
• Time: 9:40 p.m. ET
• Venue: Petco Park -- San Diego, California
• Coverage: Padres.TV and Nationals.TV

Padres vs Nationals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SD: (-188) | WSH: (+158)
• Spread: SD: -1.5 (+122) | WSH: +1.5 (-146)
• Total: 7.5 -- Over: (-120) | Under: (-102)

Padres vs Nationals Probable Starting Pitchers

Probable Pitchers: Casey Mize (Padres) - 5-9, 3.64 ERA vs Riley Cornelio (Nationals) - 2-2, 5.96 ERA

The probable starters are Casey Mize (5-9) for the Padres and Riley Cornelio (2-2) for the Nationals. Mize's team is 11-11-0 against the spread in his starts this season. Mize's team has won 50% of his starts when they are favored on the moneyline (6-6). Cornelio never pitched as a moneyline underdog a season ago.

Padres vs Nationals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Padres win (58.1%)

Padres vs Nationals Moneyline

• The moneyline numbers for Padres vs. Nationals reveal San Diego as the favorite (-188) and Washington as the underdog (+158) on the road.

Padres vs Nationals Spread

• The Padres are favored by 1.5 runs at home versus the Nationals. The Padres are +122 to cover the spread, while the Nationals are -146.

Padres vs Nationals Over/Under

• The Padres-Nationals game on Sept. 8 has been given an over/under of 7.5 runs. The over is set at -120 and the under at -102.

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Padres vs Nationals Betting Trends

• The Padres have been victorious in 37, or 56.1%, of the 66 contests they have been chosen as favorites in this season.
• This season San Diego has been victorious four times in five chances when named as a favorite of at least -188 on the moneyline.
• The Padres and their opponents have hit the over in 62 of their 144 games with a total set by oddsmakers this season.
• In 144 games with a line this season, the Padres have a mark of 83-61-0 against the spread.
• The Nationals have won 48 of the 111 games they were the underdog on the moneyline this season (43.2%).
• When playing as a moneyline underdog with odds of +158 or longer, Washington has a 7-15 record (winning just 31.8% of its games).
• The Nationals have played in 142 games with a set over/under, and have combined with opponents to go over the total 73 times (73-63-6).
• The Nationals have a 79-63-0 record against the spread this season.

Padres Player Leaders

• Fernando Tatis Jr. leads San Diego with 158 hits and an OBP of .349, plus a team-best slugging percentage of .450. He's batting .283.
• Among qualifying hitters in MLB, his batting average ranks 16th, his on-base percentage ranks 44th, and he is 47th in slugging.
• Tatis will look for his third straight game with a hit in this matchup. During his last five outings he is batting .316 with a home run, a walk and two RBIs.
• Manny Machado is hitting .224 with 22 doubles, 26 home runs and 69 walks. He's slugging .416 with an on-base percentage of .312.
• His batting average is 120th among qualified players, his on-base percentage 101st, and his slugging percentage 76th.
• Machado brings a four-game streak with at least one hit into this contest. In his last five games he is hitting .333 with a double, two home runs, four walks and four RBIs.
• Jackson Merrill has collected 131 base hits, an OBP of .293 and a slugging percentage of .415 this season.
• Ty France has 20 home runs, 62 RBI and a batting average of .288 this season.

Nationals Player Leaders

• James Wood has racked up a team-high OBP (.394), and paces the Nationals in hits (122). He's batting .268 and slugging.
• Including all the qualified players in MLB, he ranks 46th in batting average, third in on-base percentage and fourth in slugging percentage.
• Wood heads into this matchup on a six-game hitting streak. In his last 10 outings he is batting .222 with three doubles, eight walks and two RBIs.
• C.J. Abrams is batting .262 with 26 doubles, three triples, 30 home runs and 52 walks. He's slugging .496 with an on-base percentage of .340.
• Including all qualified hitters, he is 60th in batting average, 52nd in on-base percentage and 15th in slugging percentage.
• Daylen Lile has racked up a slugging percentage of .440, a team-best for the Nationals.
• Jacob Young is batting .249 with 19 doubles, three triples, 10 home runs and 32 walks.

Padres vs Nationals Head to Head

• 9/7/2026: 3-2 SD (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -198, Underdog Moneyline: +166)
• 5/31/2026: 4-2 WSH (Favorite: Padres, Spread: -1.5, Total: 9.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 5/30/2026: 9-4 WSH (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 5/29/2026: 7-5 SD (Favorite: Nationals, Spread: -1.5, Total: 9.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 7/20/2025: 8-1 SD (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 7/18/2025: 7-2 SD (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 6/25/2025: 1-0 SD (Favorite: Padres, Spread: -1.5, Total: 7, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 6/24/2025: 4-3 SD (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 6/23/2025: 10-6 WSH (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 7/25/2024: 3-0 SD (Favorite: Padres, Spread: -1.5, Total: 9, Favorite Moneyline: -162, Underdog Moneyline: +136)

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