Padres vs Nationals Prediction, Odds, Moneyline, Spread & Over/Under for June 23

Odds updated as of 8:15 a.m.

The MLB slate on Monday includes the San Diego Padres taking on the Washington Nationals.

All the info you need to make smart wagers on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Padres vs Nationals Game Info

• San Diego Padres (42-35) vs. Washington Nationals (32-46)
• Date: Monday, June 23, 2025
• Time: 9:40 p.m. ET
• Venue: PETCO Park -- San Diego, California
• Coverage: SDPA and MASN2

Padres vs Nationals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SD: (-158) | WSH: (+134)
• Spread: SD: -1.5 (+136) | WSH: +1.5 (-164)
• Total: 8 -- Over: (-110) | Under: (-110)

Padres vs Nationals Probable Starting Pitchers

Probable Pitchers: Stephen Kolek (Padres) - 3-2, 3.59 ERA vs Mitchell Parker (Nationals) - 4-8, 4.71 ERA

The Padres will give the nod to Stephen Kolek (3-2, 3.59 ERA), who is eyeing win No. 4 on the season, and the Nationals will turn to Mitchell Parker (4-8, 4.71 ERA). Kolek's team is 6-3-0 against the spread in his starts this season. Kolek's team is 2-2 this season when he starts and they are the moneyline favorite. When Parker starts, the Nationals are 7-6-0 against the spread. The Nationals have been the underdog on the moneyline in 10 of Parker's starts this season, and they went 6-4 in those matchups.

Padres vs Nationals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Padres win (62.1%)

Padres vs Nationals Moneyline

• Looking at the moneyline for Padres-Nationals, San Diego is the favorite at -158, and Washington is +134 playing on the road.

Padres vs Nationals Spread

• The Padres are hosting the Nationals and are favored by 1.5 runs (+136 to cover) on the runline. Washington is -164 to cover.

Padres vs Nationals Over/Under

• The over/under for Padres-Nationals on June 23 is 8. The over is -110, and the under is -110.

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Padres vs Nationals Betting Trends

• The Padres have been victorious in 23, or 62.2%, of the 37 contests they have been chosen as favorites in this season.
• San Diego has a record of 13-7 in contests when oddsmakers favor them by -158 or more on the moneyline.
• The Padres and their opponents have gone over in 32 of their 76 games with a total set by sportsbooks this season.
• In 76 games with a line this season, the Padres have a mark of 42-34-0 against the spread.
• The Nationals have won 49.1% of the games this season they were the moneyline underdog (28-29).
• Washington has gone 13-17 when it has played as a moneyline underdog with odds of +134 or longer (43.3%).
• The Nationals have had an over/under set by oddsmakers 74 times, and have combined with opponents to go over the total in 37 of those games (37-36-1).
• The Nationals have covered 51.4% of their games this season, going 38-36-0 ATS.

Padres Player Leaders

• Manny Machado leads San Diego in OBP (.368), slugging percentage (.497) and total hits (89) this season. He has a .305 batting average.
• Among qualified hitters in baseball, his batting average ranks 14th, his on-base percentage ranks 27th, and he is 22nd in slugging.
• Fernando Tatis Jr. is hitting .268 with 11 doubles, a triple, 14 home runs and 37 walks, while slugging .460 with an on-base percentage of .359.
• He is 58th in batting average, 34th in on-base percentage and 52nd in slugging among qualifying hitters.
• Tatis enters this game looking to extend his two-game hit streak. In his last five games he is hitting .118 with a home run, four walks and three RBIs.
• Luis Arraez has 81 hits this season and has a slash line of .279/.309/.393.
• Arraez takes a nine-game hitting streak into this game. In his last 10 games he is hitting .289 with a double, a triple and four RBIs.
• Gavin Sheets is batting .262 with a .321 OBP and 45 RBI for San Diego this season.

Nationals Player Leaders

• James Wood has a team-high OBP (.376) and slugging percentage (.558), and paces the Nationals in hits (82, while batting .279).
• Including all the qualifying hitters in the majors, he is 40th in batting average, 22nd in on-base percentage and eighth in slugging percentage.
• C.J. Abrams is hitting .277 with 16 doubles, two triples, 11 home runs and 20 walks. He's slugging .484 with an on-base percentage of .352.
• Including all qualifying hitters, his batting average places him 45th, his on-base percentage ranks 46th, and he is 31st in slugging.
• Luis Garcia is hitting .271 with 18 doubles, seven home runs and 15 walks.
• Nathaniel Lowe is hitting .229 with 12 doubles, 13 home runs and 28 walks.

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