Padres vs Marlins Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 19

Odds updated as of 4:11 a.m.

The MLB's Saturday slate includes the San Diego Padres taking on the Miami Marlins.

We've got you covered, in terms of the most important information regarding this matchup before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Padres vs Marlins Game Info

• San Diego Padres (85-69) vs. Miami Marlins (76-78)
• Date: Saturday, September 19, 2026
• Time: 8:40 p.m. ET
• Venue: Petco Park -- San Diego, California
• Coverage: Padres.TV and Marlins.TV

Padres vs Marlins Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SD: (-156) | MIA: (+132)
• Spread: SD: -1.5 (+136) | MIA: +1.5 (-164)
• Total: 7.5 -- Over: (-115) | Under: (-105)

Padres vs Marlins Probable Starting Pitchers

Probable Pitchers: Casey Mize (Padres) - 6-9, 3.69 ERA vs Eury Pérez (Marlins) - 7-11, 3.99 ERA

The probable pitchers are Casey Mize (6-9) for the Padres and Eury Perez (7-11) for the Marlins. Mize's team is 11-13-0 against the spread this season in his starts. Mize's team has won 57.1% of his starts when they are favored on the moneyline (8-6). The Marlins have gone 13-13-0 ATS in Pérez's 26 starts that had a set spread. The Marlins have been the underdog on the moneyline in 14 of Pérez's starts this season, and they went 6-8 in those matchups.

Padres vs Marlins Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Padres win (52.2%)

Padres vs Marlins Moneyline

• Looking at the moneyline for Padres-Marlins, San Diego is the favorite at -156, and Miami is +132 playing on the road.

Padres vs Marlins Spread

• The Padres are 1.5-run home favorites on the runline against the Marlins. The Padres are +136 to cover, and the Marlins are -164.

Padres vs Marlins Over/Under

• An over/under of 7.5 has been set for Padres-Marlins on Sept. 19, with the over being -115 and the under -105.

Bet on San Diego Padres vs. Miami Marlins on FanDuel today!

Padres vs Marlins Betting Trends

• The Padres have been favorites in 76 games this season and have come away with the win 46 times (60.5%) in those contests.
• This season San Diego has been victorious 18 times in 26 chances when named as a favorite of at least -156 on the moneyline.
• Contests with the Padres have gone over the total set by oddsmakers in 72 of 154 chances this season.
• The Padres have posted a record of 89-65-0 against the spread this season.
• The Marlins have won 35 of the 86 games they were listed as the moneyline underdog this season (40.7%).
• When playing as a moneyline underdog with odds of +132 or longer, Miami has a 5-16 record (winning only 23.8% of its games).
• The Marlins have had an over/under set by oddsmakers 152 times, and have combined with opponents to go over the total in 77 of those games (77-73-2).
• The Marlins have put together a 78-74-0 record ATS this season (covering 51.3% of the time).

Padres Player Leaders

• Fernando Tatis Jr. leads San Diego with 171 hits and an OBP of .355, plus a team-best slugging percentage of .461. He's batting .285.
• Among qualified hitters in MLB, his batting average ranks 15th, his on-base percentage ranks 37th, and he is 37th in slugging.
• Tatis hopes to build on a two-game hitting streak in this matchup. During his last five outings he is batting .182 with a double, two home runs, two walks and four RBIs.
• Jackson Merrill is hitting .256 with 25 doubles, five triples, 26 home runs and 39 walks. He's slugging .448 with an on-base percentage of .304.
• He is 69th in batting average, 113th in on-base percentage and 48th in slugging among qualified hitters.
• Merrill takes a nine-game streak with at least one hit into this one. During his last 10 games he is hitting .442 with two doubles, two triples, four home runs, a walk and 14 RBIs.
• Manny Machado has collected 122 base hits, an OBP of .308 and a slugging percentage of .409 this season.
• Xander Bogaerts has 12 home runs, 56 RBI and a batting average of .228 this season.
• Bogaerts enters this matchup on a two-game hitting streak. In his last five games he is batting .389 with two doubles, a triple, a home run, three walks and two RBIs.

Marlins Player Leaders

• Otto Lopez has racked up a slugging percentage of .441, a team-high for the Marlins. He's batting .307 with an on-base percentage of .349.
• Including all the qualifying hitters in the majors, his batting average ranks fourth, his on-base percentage is 43rd, and he is 55th in slugging.
• Xavier Edwards' .361 OBP paces his team. He has a batting average of .282 while slugging .373.
• He is 20th in batting average, 28th in on-base percentage and 113th in slugging percentage in the big leagues.
• Javier Sanoja is hitting .294 with 31 doubles, five triples, nine home runs and 25 walks.
• Jakob Marsee is hitting .228 with 19 doubles, six triples, 11 home runs and 75 walks.

Padres vs Marlins Head to Head

• 9/18/2026: 8-2 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -205, Underdog Moneyline: +172)
• 7/26/2026: 5-3 SD (Favorite: Marlins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 7/25/2026: 7-2 SD (Favorite: Marlins, Spread: -1.5, Total: 8, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 7/24/2026: 4-2 SD (Favorite: Marlins, Spread: -1.5, Total: 9, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 7/23/2025: 3-2 MIA (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 7/22/2025: 4-3 MIA (Favorite: Marlins, Spread: -1.5, Total: 8, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 7/21/2025: 2-1 SD (Favorite: Marlins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 5/28/2025: 10-8 MIA (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 5/27/2025: 8-6 SD (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 5/26/2025: 4-3 SD (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -152, Underdog Moneyline: +128)

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