Padres vs Athletics Prediction, Odds, Moneyline, Spread & Over/Under for May 23

Odds updated as of 5:12 a.m.

In MLB action on Saturday, the San Diego Padres face the Athletics.

Here's what you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Padres vs Athletics Game Info

• San Diego Padres (30-20) vs. Athletics (26-25)
• Date: Saturday, May 23, 2026
• Time: 9:40 p.m. ET
• Venue: Petco Park -- San Diego, California
• Coverage: Padres.TV and NBCS-CA

Padres vs Athletics Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SD: (-108) | OAK: (-108)
• Spread: SD: +1.5 (-178) | OAK: -1.5 (+146)
• Total: 8 -- Over: (-110) | Under: (-110)

Padres vs Athletics Probable Starting Pitchers

Probable Pitchers: Lucas Giolito (Padres) - 1-0, 5.40 ERA vs J.T. Ginn (Athletics) - 2-2, 2.98 ERA

The Padres will look to Lucas Giolito (1-0) versus the Athletics and J.T. Ginn (2-2). Giolito helped his team cover the spread in his only opportunity this season as a starter. This will be Giolito's first start this season with his team as the moneyline favorite. The Athletics have a 5-3-0 record against the spread in Ginn's starts. The Athletics are 4-1 in Ginn's five starts this season that they were the underdog on the moneyline.

Padres vs Athletics Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Padres win (51.1%)

Padres vs Athletics Moneyline

• The Padres vs Athletics moneyline has the Padres as a -108 favorite, while the Athletics are a -108 underdog on the road.

Padres vs Athletics Spread

Padres vs Athletics Over/Under

• Padres versus Athletics on May 23 has an over/under of 8 runs, with the odds on the over -110 and the under set at -110.

Bet on San Diego Padres vs. Athletics on FanDuel today!

Padres vs Athletics Betting Trends

• The Padres have been victorious in 15, or 60%, of the 25 contests they have been chosen as favorites in this season.
• This season, the Padres have come away with a win 18 times in 28 chances when named as a favorite of at least -108 or shorter on the moneyline.
• The Padres and their opponents have hit the over in 22 of their 50 games with a total this season.
• The Padres have an against the spread mark of 29-21-0 in 50 games with a line this season.
• The Athletics have won 18 of the 33 games they were the moneyline underdog this season (54.5%).
• The Athletics have a record of 18-15 in games they have played as a moneyline underdog with odds of -108 or longer (54.5%).
• The Athletics have played in 51 games with a set over/under, and have combined with their opponents to go over the total 24 times (24-26-1).
• The Athletics have gone 26-25-0 ATS this season.

Padres Player Leaders

• Xander Bogaerts is hitting .243 with three doubles, seven home runs and 18 walks. He has an on-base percentage of .311 and a slugging percentage of .379.
• He ranks 99th in batting average, 114th in on-base percentage, and 108th in slugging among qualified batters in MLB.
• Gavin Sheets leads San Diego with 35 hits and an OBP of .335 this season. He's batting .254 and slugging .522.
• Among qualifying hitters, his batting average places him 77th, his on-base percentage 74th, and his slugging percentage 17th.
• Sheets brings a two-game streak with at least one hit into this contest. In his last five games he is hitting .333 with a double, two home runs, four walks and six RBIs.
• Manny Machado has 31 hits this season and has a slash line of .179/.271/.347.
• Miguel Andujar has five home runs, 17 RBI and a batting average of .289 this season.

Athletics Player Leaders

• Nick Kurtz has racked up a team-high .443 on-base percentage. He's batting .281 and slugging .489.
• Including all the qualifying hitters in MLB, his batting average ranks 36th, his on-base percentage is first, and he is 28th in slugging.
• Kurtz takes a five-game hitting streak into this game. In his last five games he is batting .389 with three doubles, six walks and eight RBIs.
• Shea Langeliers has racked up 59 hits while slugging .564. Both pace his team. He has a batting average of .314 with an on-base percentage of .387.
• He ranks eighth in batting average, 16th in on-base percentage and sixth in slugging percentage in MLB.
• Tyler Soderstrom is hitting .198 with 14 doubles, a triple, five home runs and 21 walks.
• Carlos Cortes is batting .345 with eight doubles, a triple, four home runs and 14 walks.

Padres vs Athletics Head to Head

• 5/22/2026: 7-3 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 4/9/2025: 2-1 SD (Favorite: Athletics, Spread: -1.5, Total: 10, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 4/8/2025: 10-4 OAK (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 4/7/2025: 5-4 SD (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 6/12/2024: 5-4 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -225, Underdog Moneyline: +188)
• 6/11/2024: 4-3 SD (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 6/10/2024: 6-1 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -240, Underdog Moneyline: +198)
• 9/17/2023: 10-1 SD (Favorite: Padres, Spread: -1.5, Total: 9, Favorite Moneyline: -164, Underdog Moneyline: +138)
• 9/16/2023: 5-2 SD (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 9/15/2023: 8-3 SD (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -205, Underdog Moneyline: +172)

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