Padres vs Astros Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 8

Odds updated as of 4:14 a.m.

The San Diego Padres are among the MLB teams busy on Saturday, versus the Houston Astros.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the most important info regarding this matchup.

Padres vs Astros Game Info

• San Diego Padres (60-57) vs. Houston Astros (60-57)
• Date: Saturday, August 8, 2026
• Time: 7:15 p.m. ET
• Venue: Petco Park -- San Diego, California
• Coverage: Padres.TV and SCHN

Padres vs Astros Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SD: (-110) | HOU: (+102)
• Spread: SD: +1.5 (-196) | HOU: -1.5 (+162)
• Total: 8.5 -- Over: (-110) | Under: (-110)

Padres vs Astros Probable Starting Pitchers

Probable Pitchers: Michael King (Padres) - 6-8, 3.45 ERA vs Peter Lambert (Astros) - 8-5, 3.06 ERA

The probable starters are Michael King (6-8) for the Padres and Peter Lambert (8-5) for the Astros. When King starts, his team is 7-16-0 against the spread this season. King's team has won 42.9% of his starts when they are favored on the moneyline (6-8). The Astros have a 12-7-0 ATS record in Lambert's 19 starts that had a set spread. The Astros have been the underdog on the moneyline in 10 of Lambert's starts this season, and they went 6-4 in those matchups.

Padres vs Astros Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Astros win (50%)

Padres vs Astros Moneyline

• The moneyline numbers for Padres vs. Astros reveal San Diego as the favorite (-110) and Houston as the underdog (+102) on the road.

Padres vs Astros Spread

• The Astros are 1.5-run favorites against the spread for this matchup with the Padres. The Astros are +162 to cover, while the Padres are -196 to cover as a 1.5-run underdog on the runline.

Padres vs Astros Over/Under

• The Padres-Astros game on Aug. 8 has been given an over/under of 8.5 runs. The over is set at -110 and the under at -110.

Bet on San Diego Padres vs. Houston Astros on FanDuel today!

Padres vs Astros Betting Trends

• The Padres have been chosen as favorites in 49 games this year and have walked away with the win 26 times (53.1%) in those games.
• This season San Diego has come away with a win 26 times in 49 chances when named as a favorite of at least -110 on the moneyline.
• The Padres' games have gone over the total in 54 of their 117 opportunities.
• The Padres are 64-53-0 against the spread in their 117 games that had a posted line this season.
• The Astros have won 35 of the 66 games they were listed as the moneyline underdog this season (53%).
• When playing as a moneyline underdog with odds of +102 or longer, Houston has a 26-22 record (winning 54.2% of its games).
• The Astros have played in 117 games with a set over/under, and have combined with opponents to go over the total 64 times (64-49-4).
• The Astros have a 59-58-0 record against the spread this season (covering 50.4% of the time).

Padres Player Leaders

• Fernando Tatis Jr. leads San Diego OPS (.760) this season. He has a .281 batting average, an on-base percentage of .350, and a slugging percentage of .409.
• Among all qualified hitters in the majors, his batting average ranks 30th, his on-base percentage ranks 44th, and he is 91st in slugging.
• Tatis has recorded at least one hit in four games in a row. In his last five games he is batting .238 with two doubles, two home runs, a walk and two RBIs.
• Manny Machado leads San Diego with 89 hits. He is batting .211 this season and has 43 extra-base hits. He's also slugging .423 with an on-base percentage of .298.
• He ranks 138th in batting average, 123rd in on-base percentage and 75th in slugging among qualified hitters.
• Jackson Merrill has collected 107 base hits, an OBP of .292 and a slugging percentage of .400 this season.
• Merrill takes a two-game hitting streak into this game. In his last five games he is hitting .333 with a triple, a walk and four RBIs.
• Xander Bogaerts has been key for San Diego with 86 hits, an OBP of .321 plus a slugging percentage of .324.

Astros Player Leaders

• Yordan Alvarez has accumulated an on-base percentage of .442, a slugging percentage of .636, and has 137 hits, all club-bests for the Astros (while batting .328).
• Including all qualifying hitters in the big leagues, he is first in batting average, first in on-base percentage and first in slugging percentage.
• Alvarez hopes to build on a seven-game hitting streak in this matchup. In his last 10 outings he is batting .378 with four doubles, a home run, 12 walks and nine RBIs.
• Isaac Paredes is batting .253 with 19 doubles, a triple, 15 home runs and 45 walks. He's slugging .417 with an on-base percentage of .348.
• He ranks 80th in batting average, 48th in on-base percentage and 84th in slugging percentage in the majors.
• Christian Walker is batting .240 with 24 doubles, a triple, 22 home runs and 40 walks.
• Jeremy Pena is batting .306 with 12 doubles, a triple, 13 home runs and 21 walks.

Padres vs Astros Head to Head

• 8/7/2026: 6-3 HOU (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -110, Underdog Moneyline: +102)
• 4/20/2025: 3-2 SD (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 4/19/2025: 3-2 HOU (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 4/18/2025: 6-4 HOU (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 9/18/2024: 4-0 SD (Favorite: Padres, Spread: -1.5, Total: 6.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 9/17/2024: 4-3 HOU (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 9/16/2024: 3-1 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 9/10/2023: 12-2 HOU (Favorite: Astros, Spread: -1.5, Total: 10, Favorite Moneyline: -188, Underdog Moneyline: +158)
• 9/9/2023: 7-5 HOU (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 9/8/2023: 11-2 SD (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -142, Underdog Moneyline: +120)

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