Orioles vs Guardians Prediction, Odds, Moneyline, Spread & Over/Under for April 15

Odds updated as of 7:11 p.m.

In MLB action on Tuesday, the Baltimore Orioles play the Cleveland Guardians.

Here's what you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Orioles vs Guardians Game Info

• Baltimore Orioles (6-9) vs. Cleveland Guardians (8-7)
• Date: Tuesday, April 15, 2025
• Time: 7:05 p.m. ET
• Venue: Oriole Park at Camden Yards -- Baltimore, Maryland
• Coverage: TBS, MASN2, and CLEG

Orioles vs Guardians Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: BAL: (-152) | CLE: (+128)
• Spread: BAL: -1.5 (+146) | CLE: +1.5 (-176)
• Total: 8.5 -- Over: (-122) | Under: (-100)

Orioles vs Guardians Probable Starting Pitchers

Probable Pitchers: Charlie Morton (Orioles) - 0-3, 8.78 ERA vs Logan Allen (Guardians) - 0-1, 3.60 ERA

This contest's pitching matchup is set, as the Orioles will send Charlie Morton (0-3) to the mound, while Logan Allen (0-1) will get the nod for the Guardians. Morton's team has not covered in any of his three starts with a spread this season. Morton's team is 0-2 this season when he starts and they're favored on the moneyline. Allen has started two games with set spreads, and the Guardians failed to cover in both opportunities. The Guardians were the underdog on the moneyline for one Allen start this season -- they lost.

Orioles vs Guardians Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Guardians win (50.5%)

Orioles vs Guardians Moneyline

• Baltimore is a -152 favorite on the moneyline, while Cleveland is a +128 underdog on the road.

Orioles vs Guardians Spread

• The Guardians are at +1.5 on the runline against the Orioles. The Guardians are -176 to cover the spread, and the Orioles are +146.

Orioles vs Guardians Over/Under

• Orioles versus Guardians, on April 15, has an over/under of 8.5, with the over being -122 and the under -100.

Bet on Baltimore Orioles vs. Cleveland Guardians on FanDuel today!

Orioles vs Guardians Betting Trends

• The Orioles have been chosen as favorites in six games this year and have walked away with the win two times (33.3%) in those games.
• Oddsmakers have given Baltimore the best odds of winning it has seen this season, with a -152 moneyline listed for this contest.
• The Orioles' games have gone over the total in nine of their 15 opportunities.
• In 15 games with a line this season, the Orioles have a mark of 5-10-0 against the spread.
• The Guardians have won 28.6% of the games this season they were the moneyline underdog (2-5).
• When playing as a moneyline underdog with odds of +128 or longer, Cleveland has a 1-2 record (winning just 33.3% of its games).
• The Guardians have had an over/under set by oddsmakers 15 times, and have combined with opponents to go over the total in seven of those games (7-8-0).
• The Guardians have a 6-9-0 record ATS this season (covering 40% of the time).

Orioles Player Leaders

• Cedric Mullins leads Baltimore in OBP (.414) and total hits (13) this season. He's batting .277 batting average while slugging .553.
• Among the qualifying hitters in the majors, his batting average ranks 59th, his on-base percentage ranks 17th, and he is 24th in slugging.
• Adley Rutschman has an OPS of .807, fueled by an OBP of .344 and a team-best slugging percentage of .463 this season. He's batting .259.
• He ranks 69th in batting average, 60th in on-base percentage and 62nd in slugging among qualified hitters.
• Rutschman brings an eight-game streak with at least one hit into this one. In his last 10 outings he is hitting .237 with a double, a home run, five walks and three RBI.
• Tyler O'Neill is batting .289 with a .533 slugging percentage and eight RBI this year.
• Jordan Westburg is batting .231 with a .298 OBP and four RBI for Baltimore this season.

Guardians Player Leaders

• Steven Kwan has put up a .375 on-base percentage and a .441 slugging percentage, both team-best averages for the Guardians. He's batting .322.
• He is 18th in batting average, 42nd in on-base percentage and 68th in slugging percentage among all qualified batters in the big leagues.
• Kwan hopes to build on a four-game hitting streak in this matchup. In his last five games he is hitting .333 with a home run, a walk and five RBI.
• Kyle Manzardo leads his team with nine hits. He has a batting average of .196 while slugging .522 with an on-base percentage of .339.
• Including all qualified hitters, he is 135th in batting average, 66th in on-base percentage and 39th in slugging percentage.
• Jose Ramirez is hitting .229 with two doubles, four home runs and six walks.
• Carlos Santana has two doubles, two home runs and seven walks while batting .250.

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