NFL Games This Sunday: Predictions, Odds, Picks, Best Bets for Week 2

The Week 2 NFL Sunday slate has plenty of excitement, including a matchup between the Seattle Seahawks and the Arizona Cardinals.

Here is everything you need to know regarding the betting odds for Sunday.

Falcons vs. Panthers

When the Carolina Panthers (0-1) and the Atlanta Falcons (0-1) match up on Sunday, Sept. 20 at 1 p.m. ET, they will both be looking to rebound after losing their last game. The Panthers lost 59-37 to the Bears, and the Falcons are coming off a 20-13 loss to the Steelers.

• Game Preview: Carolina Panthers at Atlanta Falcons
• Projected Favorite: Panthers (53.03% win probability)
• Spread: Carolina (-2.5)
• Total: 43.5 -- Over: (-115) | Under: (-105)
• Time: 1 p.m. ET
• Channel: FOX

Bet on Atlanta vs. Carolina with FanDuel Sportsbook.

Patriots vs. Steelers

On Sunday, Sept. 20 at 1 p.m. ET, the New England Patriots (0-1) will look to bounce back from their recent 13-10 loss to the Seahawks when they square off against the Pittsburgh Steelers (1-0) at Gillette Stadium. The Steelers won their last contest 20-13 versus the Falcons.

• Game Preview: Pittsburgh Steelers at New England Patriots
• Projected Favorite: Patriots (70.73% win probability)
• Spread: New England (-4.5)
• Total: 41.5 -- Over: (-110) | Under: (-110)
• Time: 1 p.m. ET
• Channel: CBS

Bet on New England vs. Pittsburgh with FanDuel Sportsbook.

Buccaneers vs. Browns

The Tampa Bay Buccaneers (0-1), who were defeated by the Bengals in their previous tilt, host the Cleveland Browns (0-1) at Raymond James Stadium on Sept. 20 at 1 p.m. ET. The Browns took the L against the Jaguars in their last game.

• Game Preview: Cleveland Browns at Tampa Bay Buccaneers
• Projected Favorite: Buccaneers (67.77% win probability)
• Spread: Tampa Bay (-8.5)
• Total: 41.5 -- Over: (-105) | Under: (-115)
• Time: 1 p.m. ET
• Channel: CBS

Bet on Tampa Bay vs. Cleveland with FanDuel Sportsbook.

Jets vs. Packers

When the Green Bay Packers (0-1) and the New York Jets (1-0) play on Sunday, Sept. 20 at 1 p.m. ET, the Packers will be trying to bounce back from a loss to the Vikings, and the Jets will be looking to follow up their recent victory over the Titans with another win.

• Game Preview: Green Bay Packers at New York Jets
• Projected Favorite: Packers (64.04% win probability)
• Spread: Green Bay (-3.5)
• Total: 44.5 -- Over: (-115) | Under: (-105)
• Time: 1 p.m. ET
• Channel: FOX

Bet on New York vs. Green Bay with FanDuel Sportsbook.

Ravens vs. Saints

On Sunday, Sept. 20 at 1 p.m. ET, the Baltimore Ravens (1-0) will try to build upon their recent 41-23 win over the Colts when they take on the New Orleans Saints (0-1) at M&T Bank Stadium. The Saints lost their last game 31-30 to the Lions.

• Game Preview: New Orleans Saints at Baltimore Ravens
• Projected Favorite: Ravens (72.49% win probability)
• Spread: Baltimore (-8.5)
• Total: 46.5 -- Over: (-115) | Under: (-105)
• Time: 1 p.m. ET
• Channel: CBS

Bet on Baltimore vs. New Orleans with FanDuel Sportsbook.

Titans vs. Eagles

Dallas Goedert will lead the Philadelphia Eagles (1-0) into their battle versus the Tennessee Titans (0-1) at Nissan Stadium on Sunday at 1 p.m. ET.

• Game Preview: Philadelphia Eagles at Tennessee Titans
• Projected Favorite: Eagles (73.15% win probability)
• Spread: Philadelphia (-7)
• Total: 39.5 -- Over: (-110) | Under: (-110)
• Time: 1 p.m. ET
• Channel: FOX

Bet on Tennessee vs. Philadelphia with FanDuel Sportsbook.

Bears vs. Vikings

On Sunday at 1 p.m. ET, two of the best offensive players in football will be on display when QB Caleb Williams and the Chicago Bears (1-0) host pass-catcher Justin Jefferson and the Minnesota Vikings (1-0).

• Game Preview: Minnesota Vikings at Chicago Bears
• Projected Favorite: Bears (66.38% win probability)
• Spread: Chicago (-4.5)
• Total: 48.5 -- Over: (-105) | Under: (-115)
• Time: 1 p.m. ET
• Channel: FOX

Bet on Chicago vs. Minnesota with FanDuel Sportsbook.

Texans vs. Bengals

The Houston Texans (0-1), who were taken down by the Bills in their last contest, host the Cincinnati Bengals (1-0) at NRG Stadium on Sept. 20 at 1 p.m. ET. The Bengals defeated the Buccaneers in their last game.

• Game Preview: Cincinnati Bengals at Houston Texans
• Projected Favorite: Texans (73.19% win probability)
• Spread: Houston (-2.5)
• Total: 45.5 -- Over: (-115) | Under: (-105)
• Time: 1 p.m. ET
• Channel: CBS

Bet on Houston vs. Cincinnati with FanDuel Sportsbook.

Chargers vs. Raiders

After losing 26-14 to the Cardinals in their last tilt, the Los Angeles Chargers (0-1) will host the Las Vegas Raiders (1-0), who are coming off a 27-13 win against the Dolphins. The game is set for 4:05 p.m. ET on Sunday, Sept. 20.

• Game Preview: Las Vegas Raiders at Los Angeles Chargers
• Projected Favorite: Chargers (77.67% win probability)
• Spread: Los Angeles (-6.5)
• Total: 43.5 -- Over: (-110) | Under: (-110)
• Time: 4:05 p.m. ET
• Channel: CBS

Bet on Los Angeles vs. Las Vegas with FanDuel Sportsbook.

Broncos vs. Jaguars

The Denver Broncos (0-1) are set to square off against the Jacksonville Jaguars (1-0) at Empower Field at Mile High on Sunday, Sept. 20 at 4:05 p.m. ET. In their previous games, the Broncos were defeated by the Chiefs 31-10, and the Jaguars won 34-10 against the Browns.

• Game Preview: Jacksonville Jaguars at Denver Broncos
• Projected Favorite: Broncos (55.42% win probability)
• Spread: Denver (-2.5)
• Total: 45.5 -- Over: (-105) | Under: (-115)
• Time: 4:05 p.m. ET
• Channel: CBS

Bet on Denver vs. Jacksonville with FanDuel Sportsbook.

Cowboys vs. Commanders

The Dallas Cowboys (0-1) are slated to collide with the Washington Commanders (0-1) at AT&T Stadium on Sunday, Sept. 20 at 4:25 p.m. ET. Both teams lost their previous tilt, as the Cowboys were defeated by the Giants 28-20, and the Commanders lost 24-22 to the Eagles.

• Game Preview: Washington Commanders at Dallas Cowboys
• Projected Favorite: Cowboys (62.99% win probability)
• Spread: Dallas (-3.5)
• Total: 50.5 -- Over: (-110) | Under: (-110)
• Time: 4:25 p.m. ET
• Channel: FOX

Bet on Dallas vs. Washington with FanDuel Sportsbook.

49ers vs. Dolphins

At 4:25 p.m. ET on Sunday, the San Francisco 49ers (1-0) are at home against the Miami Dolphins (0-1).

• Game Preview: Miami Dolphins at San Francisco 49ers
• Projected Favorite: 49ers (77.10% win probability)
• Spread: San Francisco (-13.5)
• Total: 45.5 -- Over: (-110) | Under: (-110)
• Time: 4:25 p.m. ET
• Channel: FOX

Bet on San Francisco vs. Miami with FanDuel Sportsbook.

Cardinals vs. Seahawks

The Seattle Seahawks (1-0), who defeated against the Patriots in their previous contest, visit the Arizona Cardinals (1-0) at State Farm Stadium on Sept. 20 at 4:25 p.m. ET. The Cardinals picked up the W against the Chargers in their last game.

• Game Preview: Seattle Seahawks at Arizona Cardinals
• Projected Favorite: Seahawks (65.46% win probability)
• Spread: Seattle (-4.5)
• Total: 41.5 -- Over: (-102) | Under: (-120)
• Time: 4:25 p.m. ET
• Channel: FOX

Bet on Arizona vs. Seattle with FanDuel Sportsbook.

Chiefs vs. Colts

Kenneth Walker III and the Kansas City Chiefs (1-0) will host Jonathan Taylor and the Indianapolis Colts (0-1) on Sunday at 8:20 p.m. ET, in a battle featuring two excellent running backs.

• Game Preview: Indianapolis Colts at Kansas City Chiefs
• Projected Favorite: Chiefs (58.58% win probability)
• Spread: Kansas City (-6.5)
• Total: 46.5 -- Over: (-110) | Under: (-110)
• Time: 8:20 p.m. ET
• Channel: NBC/Peacock

Bet on Kansas City vs. Indianapolis with FanDuel Sportsbook.

Matchup favorites and win projections are provided by numberFire.

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!