Friday’s MLB Strikeout Props - Sept. 26

Will Joe Ryan strike out more than 6.5 batters? Can Kyle Hendricks exceed 3.5 strikeouts? See their odds and more strikeout prop odds for all pitchers in MLB play on Sept. 26, in the article below.

Today's MLB Strikeout Props

Arizona Diamondbacks at San Diego Padres

• Zac Gallen (Diamondbacks): Over/Under 4.5 Ks (Over +118, Under -158) | 2025 Stats: 5.4 strikeouts per game in 32 appearances
• Yu Darvish (Padres): Over/Under 4.5 Ks (Over -128, Under -104) | 2025 Stats: 4.6 strikeouts per game in 14 appearances

Pittsburgh Pirates at Atlanta Braves

• Joey Wentz (Braves): Over/Under 5.5 Ks (Over +104, Under -140) | 2025 Stats: 2.3 strikeouts per game in 38 appearances
• Mitch Keller (Pirates): Over/Under 4.5 Ks (Over +120, Under -160) | 2025 Stats: 4.6 strikeouts per game in 31 appearances

Minnesota Twins at Philadelphia Phillies

• Joe Ryan (Twins): Over/Under 6.5 Ks (Over +132, Under -174) | 2025 Stats: 6.2 strikeouts per game in 30 appearances
• Aaron Nola (Phillies): Over/Under 5.5 Ks (Over -146, Under +110) | 2025 Stats: 5.5 strikeouts per game in 16 appearances

St. Louis Cardinals at Chicago Cubs

• Colin Rea (Cubs): Over/Under 4.5 Ks (Over +104, Under -140) | 2025 Stats: 4 strikeouts per game in 32 appearances
• Miles Mikolas (Cardinals): Over/Under 3.5 Ks (Over +110, Under -146) | 2025 Stats: 3.2 strikeouts per game in 31 appearances

Chicago White Sox at Washington Nationals

• Yoendrys Gomez (White Sox): Over/Under 4.5 Ks (Over -114, Under -114) | 2025 Stats: 2.6 strikeouts per game in 20 appearances

Tampa Bay Rays at Toronto Blue Jays

• Adrian Houser (Rays): Over/Under 3.5 Ks (Over +136, Under -182) | 2025 Stats: 4.4 strikeouts per game in 20 appearances
• Shane Bieber (Blue Jays): Over/Under 6.5 Ks (Over +110, Under -148) | 2025 Stats: 5.7 strikeouts per game in 6 appearances

Texas Rangers at Cleveland Guardians

• Jack Leiter (Rangers): Over/Under 4.5 Ks (Over -136, Under +102) | 2025 Stats: 4.9 strikeouts per game in 28 appearances
• Slade Cecconi (Guardians): Over/Under 4.5 Ks (Over -122, Under -108) | 2025 Stats: 4.8 strikeouts per game in 22 appearances

Colorado Rockies at San Francisco Giants

• German Marquez (Rockies): Over/Under 3.5 Ks (Over -158, Under +118) | 2025 Stats: 3.3 strikeouts per game in 25 appearances
• Trevor McDonald (Giants): Over/Under 4.5 Ks (Over +110, Under -148) | 2025 Stats: 2 strikeouts per game in 2 appearances

Detroit Tigers at Boston Red Sox

• Kyle Harrison (Red Sox): Over/Under 4.5 Ks (Over -112, Under -118) | 2025 Stats: 3.2 strikeouts per game in 10 appearances
• Casey Mize (Tigers): Over/Under 4.5 Ks (Over +118, Under -158) | 2025 Stats: 4.9 strikeouts per game in 27 appearances

New York Mets at Miami Marlins

• Brandon Sproat (Mets): Over/Under 3.5 Ks (Over -118, Under -112) | 2025 Stats: 5 strikeouts per game in 3 appearances
• Sandy Alcantara (Marlins): Over/Under 4.5 Ks (Over -125, Under -106) | 2025 Stats: 4.6 strikeouts per game in 30 appearances

Cincinnati Reds at Milwaukee Brewers

• Zack Littell (Reds): Over/Under 3.5 Ks (Over -108, Under -122) | 2025 Stats: 4.1 strikeouts per game in 31 appearances
• Quinn Priester (Brewers): Over/Under 4.5 Ks (Over -158, Under +118) | 2025 Stats: 4.6 strikeouts per game in 28 appearances

Los Angeles Dodgers at Seattle Mariners

• Emmet Sheehan (Dodgers): Over/Under 5.5 Ks (Over -152, Under +124) | 2025 Stats: 6.1 strikeouts per game in 14 appearances
• George Kirby (Mariners): Over/Under 5.5 Ks (Over -144, Under +116) | 2025 Stats: 5.8 strikeouts per game in 22 appearances

Kansas City Royals at Athletics

• Noah Cameron (Royals): Over/Under 4.5 Ks (Over -125, Under -104) | 2025 Stats: 4.7 strikeouts per game in 23 appearances

Baltimore Orioles at New York Yankees

• Will Warren (Yankees): Over/Under 4.5 Ks (Over -162, Under +124) | 2025 Stats: 5.1 strikeouts per game in 32 appearances
• Trevor Rogers (Orioles): Over/Under 5.5 Ks (Over +108, Under -144) | 2025 Stats: 5.9 strikeouts per game in 17 appearances

Houston Astros at Los Angeles Angels

• Jason Alexander (Astros): Over/Under 4.5 Ks (Over -104, Under -128) | 2025 Stats: 3.6 strikeouts per game in 17 appearances
• Kyle Hendricks (Angels): Over/Under 3.5 Ks (Over +126, Under -168) | 2025 Stats: 3.5 strikeouts per game in 30 appearances