Mets vs Padres Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 17

Odds updated as of 2:14 a.m.

MLB action on Wednesday includes the New York Mets taking on the San Diego Padres.

Before you do any MLB betting on this matchup at FanDuel Sportsbook, here's what you need to know.

Mets vs Padres Game Info

• New York Mets (78-73) vs. San Diego Padres (82-69)
• Date: Wednesday, September 17, 2025
• Time: 7:10 p.m. ET
• Venue: Citi Field -- Queens, New York
• Coverage: SNY and SDPA

Mets vs Padres Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: NYM: (-108) | SD: (-108)
• Spread: NYM: +1.5 (-184) | SD: -1.5 (+152)
• Total: 7.5 -- Over: (-118) | Under: (-104)

Mets vs Padres Probable Starting Pitchers

Probable Pitchers: David Peterson (Mets) - 9-5, 3.77 ERA vs Nick Pivetta (Padres) - 13-5, 2.73 ERA

This contest's pitching matchup is set, as the Mets will send David Peterson (9-5) to the mound, while Nick Pivetta (13-5) will answer the bell for the Padres. Peterson's team is 8-17-0 against the spread this season in his starts. Peterson's team has won 63.2% of his starts when they are favored on the moneyline (12-7). The Padres are 16-13-0 against the spread when Pivetta starts. The Padres have been the underdog on the moneyline in eight of Pivetta's starts this season, and they went 5-3 in those matchups.

Mets vs Padres Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Mets win (51.2%)

Mets vs Padres Moneyline

• New York is the favorite, -108 on the moneyline, while San Diego is a -108 underdog on the road.

Mets vs Padres Spread

Mets vs Padres Over/Under

• Mets versus Padres, on Sept. 17, has an over/under of 7.5, with the over being -118 and the under -104.

Bet on New York Mets vs. San Diego Padres on FanDuel today!

Mets vs Padres Betting Trends

• The Mets have been favorites in 102 games this season and have come away with the win 59 times (57.8%) in those contests.
• New York has a record of 60-44 in contests when oddsmakers favor them by -108 or more on the moneyline.
• The Mets and their opponents have hit the over in 67 of their 144 games with a total set by oddsmakers this season.
• In 144 games with a line this season, the Mets have a mark of 67-77-0 against the spread.
• The Padres have won 30 of the 63 games they were the underdog on the moneyline this season (47.6%).
• In games it has played as a moneyline underdog with odds of -108 or longer, San Diego has a 30-33 record (winning 47.6% of its games).
• In the 149 games bookmakers have set an over/under for the Padres, they have combined with opponents to go over the total 65 times (65-81-3).
• The Padres have covered 53.7% of their games this season, going 80-69-0 against the spread.

Mets Player Leaders

• Juan Soto has 140 hits and an OBP of .395, both of which lead New York hitters this season. He has a .262 batting average and a slugging percentage of .523.
• Among the qualified hitters in MLB, his batting average ranks 60th, his on-base percentage ranks second, and he is 11th in slugging.
• Francisco Lindor has an OPS of .794, fueled by an OBP of .340 and a team-best slugging percentage of .454 this season. He's batting .265.
• Among all qualifying players, he ranks 47th in batting average, 52nd in on-base percentage and 56th in slugging percentage.
• Lindor has picked up a hit in five straight games. During his last five outings he is batting .316 with a double, a home run, three walks and an RBI.
• Pete Alonso is batting .268 with a .515 slugging percentage and 118 RBI this year.
• Alonso heads into this matchup with three games in a row with at least one hit. In his last five games he is hitting .250 with two home runs, a walk and five RBIs.
• Brandon Nimmo has 23 home runs, 83 RBI and a batting average of .262 this season.
• Nimmo heads into this game on a three-game hitting streak. During his last five outings he is batting .300 with a home run and three RBIs.

Padres Player Leaders

• Fernando Tatis Jr. has 27 doubles, two triples, 22 home runs and 86 walks while batting .262. He's slugging .434 with an on-base percentage of .365.
• Including all the qualified hitters in MLB, he ranks 60th in batting average, 13th in on-base percentage and 72nd in slugging percentage.
• Manny Machado's 160 hits pace his team. He has a batting average of .276 while slugging .463 with an on-base percentage of .338.
• Including all qualifying hitters, his batting average places him 30th, his on-base percentage ranks 56th, and he is 46th in slugging.
• Luis Arraez has put up a team-high .386 slugging percentage.
• Ramon Laureano is hitting .286 with 25 doubles, two triples, 23 home runs and 33 walks.

Mets vs Padres Head to Head

• 9/16/2025: 8-3 NYM (Favorite: Mets, Spread: -1.5, Total: 7.5, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 7/30/2025: 5-0 SD (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 7/29/2025: 7-1 SD (Favorite: Mets, Spread: -1.5, Total: 8.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 7/28/2025: 7-6 SD (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 8/25/2024: 3-2 SD (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 8/24/2024: 7-1 NYM (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 8/23/2024: 7-0 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 8/22/2024: 8-3 NYM (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 6/16/2024: 11-6 NYM (Favorite: Padres, Spread: -1.5, Total: 7, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 6/15/2024: 5-1 NYM (Favorite: Mets, Spread: -1.5, Total: 8.5, Favorite Moneyline: -136, Underdog Moneyline: +116)

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