Memphis vs Tulane Prediction, College Football Picks, Odds and Best Bets for Friday Night

Memphis vs Tulane Prediction in Summary

• Memphis -6.5
• Memphis Moneyline
• Over 54.5
• Memphis Over 420.5 Total Yards
• Prediction: Memphis wins a high-scoring game on the road

Memphis travels to Tulane Friday night, and the market sees a real gap between the two sides — a -260 road favorite laying 6.5 points, with a total near 55 signaling that both offenses are expected to find the end zone with regularity.

All college football odds come from FanDuel Sportsbook's college football betting odds and may change after this article is published.

Memphis vs Tulane Odds

Memphis at Tulane (Fri, 7:30 p.m. ET)

Memphis -6.5 (-122)

Memphis's own total yardage line (420.5) sits well above Tulane's (371.5), a clear sign the market expects a real edge on both sides of the ball on the road.

Memphis Moneyline (-260)

A real, meaningful favorite on the road, backed up by Memphis's own rushing production (179.5 yards favored to clear) as a genuine foundation for this offense.

Over 54.5 (-110)

One of the higher totals of the entire college football slate tonight, a real sign the market expects both offenses to find the end zone with real regularity.

Memphis 420.5+ Total Yards (-114)

Memphis's own yardage line sits nearly 50 yards above Tulane's, a real sign the road team is expected to put together a genuinely productive offensive night.

Memphis vs Tulane Prediction

Memphis's real advantage on paper — both in moneyline price and projected yardage — points to a comfortable road win. With the total sitting near 55, expect Tulane's offense to stay involved enough to keep this from becoming a complete blowout, even as Memphis pulls away. Look for Memphis to cover behind a balanced offensive attack while the total pushes well past the number.