Marlins vs Nationals Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 10

Odds updated as of 2:12 a.m.

The Miami Marlins are among the MLB squads busy on Wednesday, versus the Washington Nationals.

Here's everything you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Marlins vs Nationals Game Info

• Miami Marlins (66-79) vs. Washington Nationals (60-84)
• Date: Wednesday, September 10, 2025
• Time: 6:40 p.m. ET
• Venue: loanDepot park -- Miami, Florida
• Coverage: FDSFL and MASN2

Marlins vs Nationals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: MIA: (-162) | WSH: (+136)
• Spread: MIA: -1.5 (+122) | WSH: +1.5 (-146)
• Total: 8.5 -- Over: (-105) | Under: (-115)

Marlins vs Nationals Probable Starting Pitchers

Probable Pitchers: Eury Pérez (Marlins) - 6-5, 4.66 ERA vs Jake Irvin (Nationals) - 8-11, 5.71 ERA

The Marlins will give the nod to Eury Perez (6-5, 4.66 ERA), who is eyeing win No. 7 on the season, and the Nationals will counter with Jake Irvin (8-11, 5.71 ERA). Pérez's team is 8-6-0 against the spread this season in his starts. When Perez starts a game and his team is the favorite on the moneyline, they have a record of 1-4. The Nationals have a 15-13-0 ATS record in Irvin's 28 starts that had a set spread. The Nationals have been the moneyline underdog in 27 of Irvin's starts this season, and they went 13-14 in those matchups.

Marlins vs Nationals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Marlins win (61.4%)

Marlins vs Nationals Moneyline

• The moneyline numbers for Marlins vs. Nationals reveal Miami as the favorite (-162) and Washington as the underdog (+136) on the road.

Marlins vs Nationals Spread

• The Nationals are +1.5 on the run line against the Marlins. The Nationals are -146 to cover, and the Marlins are +122.

Marlins vs Nationals Over/Under

• A combined run total of 8.5 has been set for Marlins-Nationals on Sept. 10, with the over at -105 and the under at -115.

Bet on Miami Marlins vs. Washington Nationals on FanDuel today!

Marlins vs Nationals Betting Trends

• The Marlins have been victorious in eight, or 34.8%, of the 23 contests they have been chosen as favorites in this season.
• Miami has been listed as a favorite of -162 or more on two occasions this season and lost both games.
• The Marlins' games have gone over the total in 69 of their 141 opportunities.
• The Marlins are 79-62-0 against the spread in their 141 games with a line set by sportsbooks this season.
• The Nationals have been the underdog on the moneyline 117 total times this season. They've finished 52-65 in those games.
• Washington is 24-33 (winning 42.1% of its games) when playing as a moneyline underdog of +136 or longer.
• The Nationals have combined with opponents to go over the total 74 times this season for a 74-57-7 record against the over/under.
• The Nationals have a 70-68-0 record ATS this season.

Marlins Player Leaders

• Otto Lopez is hitting .249 with 18 doubles, 14 home runs and 44 walks. He has an on-base percentage of .315 while slugging .376.
• Among qualifying hitters in baseball, his batting average ranks 93rd, his on-base percentage ranks 104th, and he is 129th in slugging.
• Lopez hopes to build on a three-game hitting streak in this matchup. In his last five games he is batting .353 with two home runs and four RBIs.
• Xavier Edwards leads Miami in slugging percentage (.348) thanks to 27 extra-base hits. He's batting .279 with an on-base percentage of .337.
• He ranks 25th in batting average, 54th in on-base percentage and 141st in slugging among qualified hitters.
• Edwards enters this game looking to extend his two-game hit streak. In his last five games he is hitting .143 with three walks and two RBIs.
• Agustin Ramirez is batting .226 with a .410 slugging percentage and 61 RBI this year.
• Eric Wagaman has nine home runs, 46 RBI and a batting average of .238 this season.

Nationals Player Leaders

• C.J. Abrams is batting .268 with 33 doubles, five triples, 17 home runs and 35 walks. He's slugging .451 with an on-base percentage of .331.
• Including all the qualified hitters in the big leagues, his batting average ranks 47th, his on-base percentage is 71st, and he is 60th in slugging.
• Abrams heads into this game on a six-game hitting streak. In his last 10 games he is hitting .289 with six doubles and three walks.
• James Wood paces his team with 140 hits and a .357 OBP, with a team-leading .473 slugging percentage. He has a batting average of .260.
• He is 73rd in batting average, 26th in on-base percentage and 34th in slugging percentage in the big leagues.
• Luis Garcia is hitting .260 with 27 doubles, a triple, 13 home runs and 26 walks.
• Josh Bell has 13 doubles, a triple, 20 home runs and 54 walks while hitting .232.

Marlins vs Nationals Head to Head

• 9/9/2025: 7-5 WSH (Favorite: Marlins, Spread: -1.5, Total: 9, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 9/8/2025: 15-7 WSH (Favorite: Marlins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 9/3/2025: 10-5 WSH (Favorite: Marlins, Spread: -1.5, Total: 9, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 9/2/2025: 5-2 WSH (Favorite: Nationals, Spread: -1.5, Total: 9, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 9/1/2025: 2-0 WSH (Favorite: Nationals, Spread: -1.5, Total: 9, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 6/15/2025: 3-1 MIA (Favorite: Nationals, Spread: -1.5, Total: 7.5, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 6/14/2025: 4-3 MIA (Favorite: Nationals, Spread: -1.5, Total: 9, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 6/13/2025: 11-9 MIA (Favorite: Nationals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 4/13/2025: 11-4 MIA (Favorite: Nationals, Spread: -1.5, Total: 8, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 4/12/2025: 7-6 MIA (Favorite: Marlins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -142, Underdog Moneyline: +120)

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