Mariners vs Angels Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 24

Odds updated as of 4:11 a.m.

MLB action on Thursday includes the Seattle Mariners playing the Los Angeles Angels.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the vital info about this matchup.

Mariners vs Angels Game Info

• Seattle Mariners (74-84) vs. Los Angeles Angels (60-98)
• Date: Thursday, September 24, 2026
• Time: 9:40 p.m. ET
• Venue: T-Mobile Park -- Seattle, Washington
• Coverage: Mariners.TV and ABTV

Mariners vs Angels Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SEA: (-198) | LAA: (+166)
• Spread: SEA: -1.5 (+116) | LAA: +1.5 (-140)
• Total: 7.5 -- Over: (+106) | Under: (-130)

Mariners vs Angels Probable Starting Pitchers

Probable Pitchers: Bryan Woo (Mariners) - 12-9, 3.92 ERA vs Grayson Rodriguez (Angels) - 4-8, 5.96 ERA

The Mariners will give the nod to Bryan Woo (12-9) against the Angels and Grayson Rodriguez (4-8). Woo's team is 14-15-0 against the spread in his starts this season. Woo's team has been victorious in 63.6% of the games he's started as the moneyline favorite with a record of 14-8. The Angels have gone 9-10-0 against the spread when Rodriguez starts. The Angels have been the moneyline underdog in 18 of Rodriguez's starts this season, and they went 4-14 in those games.

Mariners vs Angels Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Mariners win (66.7%)

Mariners vs Angels Moneyline

• Seattle is a -198 favorite on the moneyline, while Los Angeles is a +166 underdog on the road.

Mariners vs Angels Spread

• The Mariners are hosting the Angels and are favored by 1.5 runs on the spread. The Mariners are +116 to cover the runline, with the Angels being -140.

Mariners vs Angels Over/Under

• A combined run total of 7.5 has been set for Mariners-Angels on Sept. 24, with the over at +106 and the under at -130.

Bet on Seattle Mariners vs. Los Angeles Angels on FanDuel today!

Mariners vs Angels Betting Trends

• The Mariners have been victorious in 60, or 49.6%, of the 121 contests they have been chosen as favorites in this season.
• Seattle has a record of 4-3 when favored by -198 or more this year.
• Contests with the Mariners have gone over the total set by sportsbooks in 82 of 156 chances this season.
• The Mariners are 56-100-0 against the spread in their 156 games with a line set by sportsbooks this season.
• The Angels have compiled a 44-82 record in games they were listed as the moneyline underdog (winning 34.9% of those games).
• When it has played as a moneyline underdog with odds of +166 or longer, Los Angeles has gone 5-5 (50%).
• The Angels have had an over/under set by bookmakers 157 times, and have combined with opponents to go over the total in 66 of those games (66-88-3).
• The Angels have an 82-75-0 record against the spread this season.

Mariners Player Leaders

• Randy Arozarena has an OPS of .860, fueled by an OBP of .380 to go with a slugging percentage of .479. He has a .279 batting average, as well.
• Among qualifying hitters in MLB, his batting average ranks 25th, his on-base percentage ranks 10th, and he is 25th in slugging.
• Josh Naylor has hit 10 homers this season while driving in 55 runs. He's batting .266 this season and slugging .356 with an on-base percentage of .321.
• Among all qualifying players, he is 47th in batting average, 88th in on-base percentage and 125th in slugging percentage.
• Julio Rodriguez has collected 145 base hits, an OBP of .309 and a slugging percentage of .401 this season.
• Julio Rodriguez has recorded at least one base hit in four games in a row. In his last five games he is batting .421 with two doubles, a walk and two RBIs.
• Dominic Canzone leads Seattle with 121 hits, batting .262 this season with 53 extra-base hits.
• Canzone brings a 12-game hitting streak into this matchup. In his last 10 outings he is batting .342 with three doubles, a triple, a home run, five walks and nine RBIs.

Angels Player Leaders

• Zach Neto has put up a team-best slugging percentage (.432) while leading the Angels in hits (144). He's batting .238 and with an on-base percentage of .326.
• Including all qualifying players, he is 101st in batting average, while his on-base percentage ranks 76th and he is 64th in slugging.
• Mike Trout's .385 OBP paces his team. He has a batting average of .247 while slugging .430.
• He is currently 86th in batting average, sixth in on-base percentage and 65th in slugging percentage among all qualified hitters.
• Vaughn Grissom is batting .244 with 22 doubles, 13 home runs and 30 walks.
• Wade Meckler is hitting .295 with 14 doubles, three home runs and 31 walks.

Mariners vs Angels Head to Head

• 9/16/2026: 7-2 SEA (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 9/15/2026: 2-1 LAA (Favorite: Mariners, Spread: -1.5, Total: 8.5, Favorite Moneyline: -174, Underdog Moneyline: +146)
• 9/14/2026: 6-4 LAA (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 7/2/2026: 1-0 SEA (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -225, Underdog Moneyline: +188)
• 6/30/2026: 8-3 SEA (Favorite: Mariners, Spread: -1.5, Total: 7, Favorite Moneyline: -188, Underdog Moneyline: +158)
• 6/29/2026: 6-2 SEA (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -210, Underdog Moneyline: +176)
• 4/5/2026: 8-7 LAA (Favorite: Mariners, Spread: -1.5, Total: 9, Favorite Moneyline: -164, Underdog Moneyline: +138)
• 4/4/2026: 1-0 LAA (Favorite: Mariners, Spread: -1.5, Total: 9.5, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 4/3/2026: 3-1 SEA (Favorite: Mariners, Spread: -1.5, Total: 8, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 9/14/2025: 11-2 SEA (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -220, Underdog Moneyline: +184)

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!