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Indiana vs Northwestern Prediction, Odds, Picks, Best Bets for Week 4 2026
The Indiana Hoosiers will face the Northwestern Wildcats in college football action on Friday.
We've got you covered, in terms of the vital info about NCAA football betting lines, before you make your wager on FanDuel Sportsbook.
Indiana vs Northwestern Odds & Spread
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- All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
- Moneyline: Indiana: (-2500) | Northwestern: (+1100)
- Spread: Indiana: -20.5 (-122) | Northwestern: +20.5 (100)
- Total: 49.5 -- Over: (-110) | Under: (-110)
Indiana vs Northwestern Betting Trends
- Indiana hasn't won a game against the spread this season.
- Indiana has no wins ATS (0-3) as a 20.5-point favorite or greater this year.
- Indiana has had one game (of three) hit the over this year.
- Northwestern has covered the spread in every game this season.
- Northwestern has had one game (of two) hit the over this season.
Indiana vs Northwestern Prediction & Pick
All college football win probability predictions and picks are according to numberFire.
Prediction: Hoosiers win (86.7%)
Indiana vs Northwestern Point Spread
Northwestern is an underdog by 20.5 points versus Indiana. Northwestern is +100 to cover the spread, and Indiana is -122.
Indiana vs Northwestern Over/Under
The over/under for Indiana-Northwestern on Sept. 25 is 49.5. The over is -110, and the under is -110.
Indiana vs Northwestern Moneyline
The moneyline numbers for Indiana vs. Northwestern reveal Indiana as the favorite (-2500) and Northwestern as the underdog (+1100).
Indiana vs. Northwestern Points Insights
Point Scored (PG) | Points Scored CFB Rank | Points Allowed (PG) | Points Allowed CFB Rank | Average Total | Total Games | |
|---|---|---|---|---|---|---|
| Indiana | 48.3 | 7 | 5.3 | 2 | 61.5 | 3 |
| Northwestern | 37.5 | 98 | 12.5 | 7 | 49.0 | 2 |
Indiana vs. Northwestern Game Info
- Game day: Friday, September 25, 2026
- Game time: 8 p.m. ET
- TV channel: FOX
- Location: Bloomington, Indiana
- Stadium: Memorial Stadium (Bloomington, IN)
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Check out even more in-depth Indiana vs. Northwestern analysis on FanDuel Research.
