Clemson vs Cal Prediction, Odds, Picks, Best Bets for Week 4 2026

In college football action on Friday, the Clemson Tigers face the California Golden Bears.

We've got you covered, in terms of the vital information about NCAA football betting lines, before you make your wager on FanDuel Sportsbook.

Clemson vs Cal Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Clemson: (-111) | Cal: (-108)
• Spread: Clemson: -1.5 (-104) | Cal: +1.5 (-118)
• Total: 50.5 -- Over: (-110) | Under: (-110)

Clemson vs Cal Betting Trends

• Clemson has one win against the spread this year.
• Clemson owns one win ATS (1-1) as a 1.5-point favorite or greater this season.
• Two of three Clemson games have hit the over this year.
• Cal has but one win versus the spread this year.
• As a 1.5-point underdog or more, Cal has one win ATS (1-1) this season.
• One of Cal's three games has hit the over.

Clemson vs Cal Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Tigers win (63%)

Clemson vs Cal Point Spread

Clemson is favored by 1.5 points (-104 to cover) in this matchup. Cal, the underdog, is -118.

Clemson vs Cal Over/Under

The Clemson-Cal matchup on Sept. 25 has been given an over/under of 50.5 points. The over is -110 and the under is -110.

Clemson vs Cal Moneyline

Looking at the moneyline for Clemson-Cal, Clemson is the favorite at -111, and Cal is -108.

Clemson vs. Cal Points Insights

Clemson vs. Cal Game Info

• Game day: Friday, September 25, 2026
• Game time: 10:30 p.m. ET
• TV channel: ESPN
• Location: Berkeley, California
• Stadium: California Memorial Stadium

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Check out even more in-depth Clemson vs. Cal analysis on FanDuel Research.