Guardians vs Reds Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 25

Odds updated as of 4:11 p.m.

The Cleveland Guardians are among the MLB teams playing on Wednesday, versus the Cincinnati Reds.

Before you do any MLB betting on this matchup at FanDuel Sportsbook, here's everything you need to know.

Guardians vs Reds Game Info

• Cleveland Guardians (91-67) vs. Cincinnati Reds (76-82)
• Date: Wednesday, September 25, 2024
• Time: 6:40 p.m. ET
• Venue: Progressive Field -- Cleveland, Ohio
• Coverage: BSGL

Guardians vs Reds Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CLE: (-146) | CIN: (+124)
• Spread: CLE: -1.5 (+140) | CIN: +1.5 (-170)
• Total: 7.5 -- Over: (-118) | Under: (-104)

Guardians vs Reds Probable Starting Pitchers

Probable Pitchers: Andrew Walters (Guardians) - 1-0, 0.00 ERA vs Jakob Junis (Reds) - 4-0, 2.61 ERA

This contest's pitching matchup is set, as the Guardians will send Andrew Walters (1-0) to the mound, while Jakob Junis (4-0) will take the ball for the Reds. Walters did not pitch as the moneyline favorite in any games last season. The Reds are 1-3-0 ATS in Junis' four starts with a set spread. The Reds were named the moneyline underdog for two Junis starts this season -- they lost both.

Guardians vs Reds Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Reds win (50.3%)

Guardians vs Reds Moneyline

• Cincinnati is a +124 underdog on the moneyline, while Cleveland is a -146 favorite at home.

Guardians vs Reds Spread

• The Reds are at the Guardians, and are +1.5 on the runline. The Reds are +140 to cover the spread, and the Guardians are -170.

Guardians vs Reds Over/Under

• Guardians versus Reds on Sept. 25 has an over/under of 7.5 runs, with the odds on the over -118 and the under set at -104.

Bet on Cleveland Guardians vs. Cincinnati Reds on FanDuel today!

Guardians vs Reds Betting Trends

• The Guardians have won in 62, or 66%, of the 94 contests they have been named as odds-on favorites in this year.
• Cleveland has a record of 24-12 when favored by -146 or more this year.
• The Guardians and their opponents have hit the over in 70 of their 156 games with a total set by oddsmakers this season.
• The Guardians are 84-72-0 against the spread in their 156 games with a line set by sportsbooks this season.
• The Reds have put together a 38-45 record in games they were the underdog on the moneyline (winning 45.8% of those games).
• When playing as a moneyline underdog with odds of +124 or longer, Cincinnati has gone 17-17 (50%).
• The Reds have combined with opponents to go over the total 72 times this season for a 72-73-7 record against the over/under.
• The Reds have covered 55.9% of their games this season, going 85-67-0 ATS.

Guardians Player Leaders

• Jose Ramirez leads Cleveland with 168 hits and a team-best slugging percentage of .521. He's batting .275 with an on-base percentage of .332.
• Among qualified hitters in baseball, he ranks 31st in batting average, 50th in on-base percentage, and 12th in slugging.
• Josh Naylor has 27 doubles, 31 home runs and 57 walks. He's batting .243 and slugging .460 with an on-base percentage of .319.
• He is 95th in batting average, 81st in on-base percentage and 39th in slugging among qualifying hitters.
• Andres Gimenez has collected 146 base hits, an OBP of .302 and a slugging percentage of .344 this season.
• Lane Thomas is batting .241 with a .313 OBP and 63 RBI for Cleveland this season.

Reds Player Leaders

• Elly De La Cruz has a team-best slugging percentage (.473) and paces the Reds in hits (156). He's batting .260 and with an on-base percentage of .341.
• Including all the qualifying players in the big leagues, his batting average is 56th, his on-base percentage ranks 36th, and he is 26th in slugging.
• Spencer Steer is hitting .229 with 34 doubles, four triples, 20 home runs and 71 walks. He's slugging .412 with an on-base percentage of .324.
• His batting average ranks 116th among all qualified players, his on-base percentage is 70th, and he is 77th in slugging.
• Jonathan India has accumulated a team-high .354 on-base percentage.
• Tyler Stephenson is batting .262 with 26 doubles, a triple, 19 home runs and 45 walks.

Guardians vs Reds Head to Head

• 9/24/2024: 6-1 CLE (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -196, Underdog Moneyline: +164)
• 6/12/2024: 4-2 CIN (Favorite: Reds, Spread: -1.5, Total: 8, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 6/11/2024: 5-3 CLE (Favorite: Reds, Spread: -1.5, Total: 9, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 9/27/2023: 4-3 CLE (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 9/26/2023: 11-7 CIN (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 8/16/2023: 7-2 CIN (Favorite: Reds, Spread: -1.5, Total: 9.5, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 8/15/2023: 3-0 CLE (Favorite: Reds, Spread: -1.5, Total: 9.5, Favorite Moneyline: -120, Underdog Moneyline: +102)

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