Guardians vs Mariners Prediction, Odds, Moneyline, Spread & Over/Under for June 26

Odds updated as of 2:12 p.m.

The Cleveland Guardians versus the Seattle Mariners is on the MLB schedule for Friday.

Before you do any MLB betting on this matchup at FanDuel Sportsbook, here's everything you need to know.

Guardians vs Mariners Game Info

• Cleveland Guardians (42-39) vs. Seattle Mariners (41-41)
• Date: Friday, June 26, 2026
• Time: 7:10 p.m. ET
• Venue: Progressive Field -- Cleveland, Ohio
• Coverage: CleGuardians.TV and Mariners.TV

Guardians vs Mariners Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CLE: (-108) | SEA: (-108)
• Spread: CLE: +1.5 (-192) | SEA: -1.5 (+158)
• Total: 7.5 -- Over: (-122) | Under: (+100)

Guardians vs Mariners Probable Starting Pitchers

Probable Pitchers: Joey Cantillo (Guardians) - 6-3, 4.05 ERA vs Luis Castillo (Mariners) - 2-6, 5.22 ERA

The probable starters are Joey Cantillo (6-3) for the Guardians and Luis Castillo (2-6) for the Mariners. Cantillo's team is 12-4-0 against the spread this season in his starts. Cantillo's team has been victorious in 66.7% of the games he's started as the moneyline favorite with a record of 4-2. The Mariners are 3-9-0 against the spread when Castillo starts. The Mariners have a 1-2 record in Castillo's three starts this season when they were the moneyline underdog.

Guardians vs Mariners Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Mariners win (57.6%)

Guardians vs Mariners Moneyline

• Looking at the moneyline for Mariners-Guardians, Seattle is the underdog at -108, and Cleveland is -108 playing at home.

Guardians vs Mariners Spread

Guardians vs Mariners Over/Under

• An over/under of 7.5 has been set for Guardians-Mariners on June 26, with the over being -122 and the under +100.

Bet on Cleveland Guardians vs. Seattle Mariners on FanDuel today!

Guardians vs Mariners Betting Trends

• The Guardians have been chosen as favorites in 41 games this year and have walked away with the win 21 times (51.2%) in those games.
• This season Cleveland has been victorious 21 times in 41 chances when named as a favorite of at least -108 on the moneyline.
• The Guardians and their opponents have gone over the total this season in 38 of their 77 opportunities.
• The Guardians are 39-38-0 against the spread in their 77 games with a line set by sportsbooks this season.
• The Mariners have won two of the seven games they were listed as the moneyline underdog this season (28.6%).
• When playing as a moneyline underdog with odds of -108 or longer, Seattle has a record of 2-5 (28.6%).
• The Mariners have had an over/under set by bookmakers 81 times, and have combined with opponents to go over the total in 38 of those games (38-40-3).
• The Mariners have covered just 35.8% of their games this season, going 29-52-0 against the spread.

Guardians Player Leaders

• Brayan Rocchio leads Cleveland OPS (.732) this season. He has a .269 batting average, an on-base percentage of .344, and a slugging percentage of .388.
• Among the qualifying hitters in baseball, his batting average ranks 47th, his on-base percentage ranks 58th, and he is 107th in slugging.
• Travis Bazzana is batting .261 with 11 doubles, a triple, seven home runs and 26 walks. He's slugging .446 with an on-base percentage of .357.
• Steven Kwan is batting .211 with a .259 slugging percentage and 13 RBI this year.
• Kwan has recorded a hit in two games in a row. In his last five games he is batting .231 with a double and two walks.
• Kyle Manzardo has been key for Cleveland with 51 hits, an OBP of .328 plus a slugging percentage of .397.

Mariners Player Leaders

• Julio Rodriguez has accumulated a slugging percentage of .423, a team-best for the Mariners. He's batting .247 with an on-base percentage of .308.
• Including all the qualifying hitters in MLB, his batting average is 91st, his on-base percentage ranks 121st, and he is 84th in slugging.
• Randy Arozarena has racked up 77 hits with a .371 on-base percentage to pace his team in both. He has a batting average of .284 while slugging .435.
• His batting average is 28th among all qualified players, his on-base percentage ranks 25th, and he is 73rd in slugging.
• Josh Naylor is hitting .258 with 10 doubles, eight home runs and 25 walks.
• Cole Young is batting .251 with 12 doubles, a triple, seven home runs and 22 walks.

Guardians vs Mariners Head to Head

• 3/29/2026: 8-0 SEA (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 3/28/2026: 6-5 CLE (Favorite: Mariners, Spread: -1.5, Total: 7, Favorite Moneyline: -178, Underdog Moneyline: +150)
• 3/27/2026: 5-1 SEA (Favorite: Mariners, Spread: -1.5, Total: 7, Favorite Moneyline: -178, Underdog Moneyline: +150)
• 3/26/2026: 6-4 CLE (Favorite: Mariners, Spread: -1.5, Total: 6.5, Favorite Moneyline: -188, Underdog Moneyline: +158)
• 8/31/2025: 4-2 SEA (Favorite: Mariners, Spread: -1.5, Total: 8, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 8/30/2025: 4-3 CLE (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 8/29/2025: 5-4 CLE (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 6/15/2025: 6-0 SEA (Favorite: Mariners, Spread: -1.5, Total: 8, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 6/14/2025: 4-3 SEA (Favorite: Mariners, Spread: -1.5, Total: 7, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 6/13/2025: 7-2 SEA (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -112, Underdog Moneyline: -104)

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