Giants vs Twins Prediction, Odds, Moneyline, Spread & Over/Under for May 10

Odds updated as of 5:12 a.m.

In MLB action on Saturday, the San Francisco Giants play the Minnesota Twins.

Here's what you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Giants vs Twins Game Info

• San Francisco Giants (24-15) vs. Minnesota Twins (19-20)
• Date: Saturday, May 10, 2025
• Time: 7:15 p.m. ET
• Venue: Target Field -- Minneapolis, Minnesota
• Coverage: FOX

Giants vs Twins Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SF: (-116) | MIN: (-102)
• Spread: SF: -1.5 (+138) | MIN: +1.5 (-166)
• Total: 8.5 -- Over: (-124) | Under: (+102)

Giants vs Twins Probable Starting Pitchers

Probable Pitchers: Logan Webb (Giants) - 4-2, 2.61 ERA vs Joe Ryan (Twins) - 2-2, 2.93 ERA

The probable pitchers are Logan Webb (4-2) for the Giants and Joe Ryan (2-2) for the Twins. Webb's team is 5-3-0 against the spread in his starts this season. Webb's team is 4-3 this season when he starts and they are the moneyline favorite. The Twins are 2-5-0 ATS in Ryan's seven starts that had a set spread. The Twins were the underdog on the moneyline for two Ryan starts this season -- they lost both.

Giants vs Twins Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Twins win (53.1%)

Giants vs Twins Moneyline

• Looking at the moneyline for Giants-Twins, San Francisco is the favorite at -116, and Minnesota is -102 playing at home.

Giants vs Twins Spread

• The Giants are favored by 1.5 runs on the road against the Twins. The Giants are +138 to cover the spread, while the Twins are -166.

Giants vs Twins Over/Under

• A total of 8.5 runs has been set for the Giants-Twins game on May 10, with the over available at -124 and the under at +102.

Bet on San Francisco Giants vs. Minnesota Twins on FanDuel today!

Giants vs Twins Betting Trends

• The Giants have been chosen as favorites in 24 games this year and have walked away with the win 16 times (66.7%) in those games.
• San Francisco has a record of 15-8 when favored by -116 or more this year.
• The Giants' games have gone over the total in 22 of their 39 opportunities.
• The Giants are 19-20-0 against the spread in their 39 games with a line set by sportsbooks this season.
• The Twins have won 36.4% of the games this season they were the underdog on the moneyline (4-7).
• In games it has played as a moneyline underdog with odds of -102 or longer, Minnesota has gone 3-5 (37.5%).
• The Twins have played in 38 games with an over/under set, and have combined with opponents to go over the total 13 times (13-22-3).
• The Twins have a 20-18-0 record ATS this season (covering 52.6% of the time).

Giants Player Leaders

• Jung Hoo Lee leads San Francisco with 43 hits and a team-best slugging percentage of .476. He's batting .293 with an on-base percentage of .344.
• Among all qualifying batters, he ranks 26th in batting average, his on-base percentage ranks 59th, and he is 38th in slugging.
• Matt Chapman is hitting .222 with five doubles, eight home runs and 29 walks, while slugging .437 with an on-base percentage of .360.
• His batting average is 125th among qualified players, his on-base percentage 45th, and his slugging percentage 60th.
• Wilmer Flores has 34 hits this season and has a slash line of .250/.301/.419.
• Michael Yastrzemski leads San Francisco with an OBP of .377 this season while batting .271 with 19 walks and 18 runs scored.

Twins Player Leaders

• Byron Buxton has accumulated a team-best slugging percentage (.550) and leads the Twins in hits (39). He's batting .279 and with an on-base percentage of .322.
• Including all the qualified hitters in the majors, his batting average places him 43rd, his on-base percentage ranks 86th, and he is 12th in slugging.
• Ty France has a .344 OBP while slugging .397. Both pace his team. He has a batting average of .277.
• His batting average ranks 46th among all qualified players, his on-base percentage ranks 59th, and he is 94th in slugging.
• Trevor Larnach is hitting .225 with two doubles, five home runs and 16 walks.
• Harrison Bader is hitting .289 with four doubles, four home runs and 12 walks.

Giants vs Twins Head to Head

• 5/9/2025: 3-1 MIN (Favorite: Giants, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 7/14/2024: 3-2 SF (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 7/13/2024: 4-2 MIN (Favorite: Giants, Spread: -1.5, Total: 8, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 7/12/2024: 7-1 SF (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 5/24/2023: 7-1 MIN (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 5/23/2023: 4-3 SF (Favorite: Twins, Spread: -1.5, Total: 8, Favorite Moneyline: -146, Underdog Moneyline: +124)
• 5/22/2023: 4-1 SF (Favorite: Twins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -164, Underdog Moneyline: +138)
• 8/28/2022: 8-3 MIN (Favorite: Twins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 8/27/2022: 3-2 MIN (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 8/26/2022: 9-0 MIN (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -134, Underdog Moneyline: +116)

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