Giants vs Angels Prediction, Odds, Moneyline, Spread & Over/Under for April 18

Odds updated as of 9:11 p.m.

The San Francisco Giants are among the MLB squads busy on Friday, up against the Los Angeles Angels.

We've got you covered, in terms of the vital info about this matchup before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Giants vs Angels Game Info

• San Francisco Giants (13-6) vs. Los Angeles Angels (9-9)
• Date: Friday, April 18, 2025
• Time: 9:38 p.m. ET
• Venue: Angel Stadium -- Anaheim, California
• Coverage: FDSW and NBCS-BA

Giants vs Angels Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SF: (-154) | LAA: (+130)
• Spread: SF: -1.5 (+104) | LAA: +1.5 (-125)
• Total: 8 -- Over: (-110) | Under: (-110)

Giants vs Angels Probable Starting Pitchers

Probable Pitchers: Logan Webb (Giants) - 2-0, 2.63 ERA vs Tyler John Anderson (Angels) - 1-0, 2.87 ERA

The Giants will give the nod to Logan Webb (2-0, 2.63 ERA), who is eyeing win No. 3 on the season, and the Angels will counter with Tyler John Anderson (1-0, 2.87 ERA). Webb's team is 3-1-0 against the spread this season in his starts. Webb's team has been victorious in 66.7% of the games he's started as the moneyline favorite with a record of 2-1. The Angels covered all of the three games Anderson has started that had a spread set by oddsmakers. The Angels won each of Anderson's three starts this season that they were the underdog on the moneyline.

Giants vs Angels Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Giants win (62.2%)

Giants vs Angels Moneyline

• The moneyline numbers for Giants vs. Angels reveal San Francisco as the favorite (-154) and Los Angeles as the underdog (+130) despite being the home team.

Giants vs Angels Spread

• The Angels are +1.5 on the run line against the Giants. The Angels are -125 to cover, and the Giants are +104.

Giants vs Angels Over/Under

• A combined run total of 8 has been set for Giants-Angels on April 18, with the over at -110 and the under at -110.

Bet on San Francisco Giants vs. Los Angeles Angels on FanDuel today!

Giants vs Angels Betting Trends

• The Giants have come away with seven wins in the nine contests they have been listed as the favorites in this season.
• San Francisco has played as a favorite of -154 or more just one time this year and came away with a loss in that game.
• The Giants and their opponents have gone over in 14 of their 19 games with a total set by sportsbooks this season.
• The Giants have posted a record of 12-7-0 against the spread this season.
• The Angels have put together a 7-7 record in games they were the underdog on the moneyline (winning 50% of those games).
• When it has played as a moneyline underdog with odds of +130 or longer, Los Angeles has a 2-2 record (winning 50% of its games).
• The Angels have combined with opponents to go over the total 10 times this season for a 10-8-0 record against the over/under.
• The Angels have an 8-10-0 record against the spread this season (covering 44.4% of the time).

Giants Player Leaders

• Jung Hoo Lee has 24 hits to go with a slugging percentage of .652, both of which lead San Francisco hitters this season. He has a .348 batting average and an on-base percentage of .403.
• Among all qualifying hitters, he is fifth in batting average, his on-base percentage ranks 17th, and he is fifth in slugging.
• Lee has recorded a base hit in three straight games. In his last five games he is batting .389 with two doubles, two home runs, a walk and seven RBI.
• Wilmer Flores is batting .239 with six home runs and three walks, while slugging .507 with an on-base percentage of .282.
• He ranks 86th in batting average, 124th in on-base percentage and 36th in slugging in MLB.
• Mike Yastrzemski leads San Francisco with an OBP of .439 this season while batting .302 with 12 walks and nine runs scored.
• Matt James Chapman is batting .239 with a .386 OBP and 12 RBI for San Francisco this season.
• Chapman enters this game on a four-game hitting streak. During his last five outings he is batting .389 with a double, a home run, four walks and four RBI.

Angels Player Leaders

• Kyren Paris is batting .326 with a double, a triple, five home runs and five walks. He's slugging .717 with an on-base percentage of .426.
• Mike Trout is batting .179 with a double, six home runs and nine walks. He's slugging .463 with an on-base percentage of .278.
• He ranks 147th in batting average, 127th in on-base percentage and 55th in slugging percentage in MLB.
• Taylor Ward is hitting .237 with three doubles, five home runs and four walks.
• Nolan Schanuel paces his team with a .347 on-base percentage, and has a club-high .441 slugging percentage.

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