Pirates vs Guardians Prediction, Odds, Moneyline, Spread & Over/Under for April 19

Odds updated as of 9:11 a.m.

The MLB's Saturday slate includes the Pittsburgh Pirates taking on the Cleveland Guardians.

Before you do any MLB betting on this matchup at FanDuel Sportsbook, here's what you need to know.

Pirates vs Guardians Game Info

• Pittsburgh Pirates (8-13) vs. Cleveland Guardians (10-9)
• Date: Saturday, April 19, 2025
• Time: 4:05 p.m. ET
• Venue: PNC Park -- Pittsburgh, Pennsylvania
• Coverage: SportsNet PT and CLEG

Pirates vs Guardians Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: PIT: (-178) | CLE: (+150)
• Spread: PIT: -1.5 (+118) | CLE: +1.5 (-142)
• Total: 8 -- Over: (-100) | Under: (-122)

Pirates vs Guardians Probable Starting Pitchers

Probable Pitchers: Paul Skenes (Pirates) - 2-1, 2.96 ERA vs Ben Lively (Guardians) - 0-2, 4.87 ERA

This contest's pitching matchup is set, as the Pirates will send Paul Skenes (2-1) to the mound, while Ben Lively (0-2) will answer the bell for the Guardians. Skenes' team is 2-2-0 against the spread this season in his starts. Skenes' team is 2-2 this season when he starts and they are the moneyline favorite. The Guardians have a 1-3-0 record against the spread in Lively's starts. The Guardians are 1-2 in Lively's three starts this season that they were the underdog on the moneyline.

Pirates vs Guardians Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Pirates win (58.5%)

Pirates vs Guardians Moneyline

• The Pirates vs Guardians moneyline has Pittsburgh as a -178 favorite, while Cleveland is a +150 underdog on the road.

Pirates vs Guardians Spread

• The Pirates are 1.5-run home favorites on the runline against the Guardians. The Pirates are +118 to cover, and the Guardians are -142.

Pirates vs Guardians Over/Under

• Pirates versus Guardians on April 19 has an over/under of 8 runs, with the odds on the over -100 and the under set at -122.

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Pirates vs Guardians Betting Trends

• The Pirates have been victorious in five of the nine contests they have been chosen as favorites in this season.
• Pittsburgh has played as a favorite of -178 or more just one time this year and came away with a win in that game.
• The Pirates' games have gone over the total in nine of their 21 opportunities.
• The Pirates have an against the spread record of 6-15-0 in 21 games with a line this season.
• The Guardians have gone 3-7 in games they were listed as the moneyline underdog (winning 30% of those games).
• Cleveland has played as a moneyline underdog of +150 or longer in only one game this season, which it lost.
• The Guardians have played in 19 games with an over/under set, and have combined with their opponents to go over the total 10 times (10-8-1).
• The Guardians have covered 42.1% of their games this season, going 8-11-0 ATS.

Pirates Player Leaders

• Oneil Cruz leads Pittsburgh in OBP (.355) and total hits (14) this season. He's batting .230 batting average while slugging .508.
• Among qualifying hitters in baseball, his batting average ranks 94th, his on-base percentage ranks 51st, and he is 37th in slugging.
• Cruz hopes to build on a three-game hitting streak in this matchup. In his last five games he is batting .300 with a double, three home runs, two walks and six RBI.
• Isiah Kiner-Falefa has an OPS of .657, fueled by an OBP of .329 and a team-best slugging percentage of .328 this season. He's batting .269.
• Among qualifying batters, his batting average places him 61st, his on-base percentage 77th, and his slugging percentage 135th.
• Kiner-Falefa takes a three-game streak with at least one hit into this matchup. In his last five games he is batting .294 with a double and an RBI.
• Ke'Bryan Hayes is batting .194 with a .284 slugging percentage and eight RBI this year.
• Enmanuel Valdez is batting .233 with a .327 OBP and nine RBI for Pittsburgh this season.
• Valdez has safely hit in three straight games. During his last five outings he is hitting .375 with two doubles, a home run, four walks and six RBI.

Guardians Player Leaders

• Steven Kwan has an on-base percentage of .378 and a slugging percentage of .467. Both lead the Guardians. He's batting .320.
• Including all qualified hitters in MLB, he is 19th in batting average, 32nd in on-base percentage and 52nd in slugging percentage.
• Jose Ramirez's 17 hits lead his team. He has a batting average of .266 while slugging .516 with an on-base percentage of .333.
• Including all qualifying hitters, he is 64th in batting average, 71st in on-base percentage and 33rd in slugging percentage.
• Kyle Manzardo has two doubles, a triple, four home runs and 11 walks while hitting .190.
• Carlos Santana is hitting .260 with two doubles, two home runs and eight walks.

Pirates vs Guardians Head to Head

• 4/18/2025: 10-7 CLE (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 9/1/2024: 6-1 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 8/31/2024: 3-0 PIT (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -190, Underdog Moneyline: +160)
• 8/30/2024: 10-8 CLE (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 7/19/2023: 7-5 PIT (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 7/18/2023: 10-1 CLE (Favorite: Pirates, Spread: -1.5, Total: 8.5, Favorite Moneyline: -112, Underdog Moneyline: -104)

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