Diamondbacks vs White Sox Prediction, Odds, Moneyline, Spread & Over/Under for June 25

Odds updated as of 2:12 a.m.

The Arizona Diamondbacks will face the Chicago White Sox in MLB action on Wednesday.

All the information you need to make smart wagers on this game at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Diamondbacks vs White Sox Game Info

• Arizona Diamondbacks (41-38) vs. Chicago White Sox (25-55)
• Date: Wednesday, June 25, 2025
• Time: 2:10 p.m. ET
• Venue: Rate Field -- Chicago, Illinois
• Coverage: CHSN and ARID

Diamondbacks vs White Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: ARI: (-142) | CHW: (+120)
• Spread: ARI: -1.5 (+118) | CHW: +1.5 (-142)
• Total: 9 -- Over: (-102) | Under: (-120)

Diamondbacks vs White Sox Probable Starting Pitchers

Probable Pitchers: Zac Gallen (Diamondbacks) - 5-8, 5.60 ERA vs Sean Burke (White Sox) - 3-7, 4.50 ERA

The Diamondbacks will give the ball to Zac Gallen (5-8, 5.60 ERA), who is eyeing win No. 6 on the season, and the White Sox will counter with Sean Burke (3-7, 4.50 ERA). Gallen's team is 6-10-0 against the spread this season in his starts. When Gallen starts a game and his team is the favorite on the moneyline, they have a record of 4-6. The White Sox have a 9-4-0 record against the spread in Burke's starts. The White Sox have been the underdog on the moneyline in 13 of Burke's starts this season, and they went 6-7 in those games.

Diamondbacks vs White Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Diamondbacks win (60.5%)

Diamondbacks vs White Sox Moneyline

• Chicago is a +120 underdog on the moneyline, while Arizona is a -142 favorite on the road.

Diamondbacks vs White Sox Spread

• The Diamondbacks are favored by 1.5 runs on the road against the White Sox. The Diamondbacks are +118 to cover the spread, while the White Sox are -142.

Diamondbacks vs White Sox Over/Under

• The over/under for the Diamondbacks versus White Sox game on June 25 has been set at 9, with -102 odds on the over and -120 odds on the under.

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Diamondbacks vs White Sox Betting Trends

• The Diamondbacks have been victorious in 28, or 54.9%, of the 51 contests they have been chosen as favorites in this season.
• This season Arizona has come away with a win 16 times in 24 chances when named as a favorite of at least -142 on the moneyline.
• The Diamondbacks and their opponents have gone over in 38 of their 76 games with a total set by sportsbooks this season.
• The Diamondbacks are 37-39-0 against the spread in their 76 games that had a posted line this season.
• The White Sox have won 30.3% of the games this season they were the moneyline underdog (23-53).
• When it has played as a moneyline underdog with odds of +120 or longer, Chicago has a 20-45 record (winning only 30.8% of its games).
• The White Sox have played in 77 games with a set over/under, and have combined with their opponents to go over the total 35 times (35-38-4).
• The White Sox have covered 54.5% of their games this season, going 42-35-0 against the spread.

Diamondbacks Player Leaders

• Geraldo Perdomo is batting .260 with 17 doubles, a triple, eight home runs and 44 walks. He has an on-base percentage of .355 while slugging .411.
• Among the qualified hitters in MLB, his batting average ranks 75th, his on-base percentage ranks 39th, and he is 93rd in slugging.
• Perdomo hopes to build on a two-game hitting streak in this matchup. During his last five outings he is hitting .273 with a double, a home run, three walks and four RBIs.
• Josh Naylor has a slash line of .303/.358/.467 this season and a team-best OPS of .824.
• He is 15th in batting average, 37th in on-base percentage and 44th in slugging among qualified hitters.
• Naylor heads into this matchup looking to extend his 12-game hit streak. In his last 10 outings he is hitting .342 with two doubles, a home run, four walks and six RBIs.
• Eugenio Suarez has 71 hits this season and has a slash line of .251/.323/.569.
• Ketel Marte has 15 home runs, 32 RBI and a batting average of .320 this season.
• Marte takes a two-game hitting streak into this game. In his last five games he is batting .571 with four doubles, three home runs, a walk and eight RBIs.

White Sox Player Leaders

• Miguel Vargas has racked up 67 hits with a .314 on-base percentage and a .426 slugging percentage, all club-highs for the White Sox. He's batting .236.
• Including all qualifying hitters in the big leagues, he ranks 126th in batting average, 106th in on-base percentage and 80th in slugging percentage.
• Andrew Benintendi is batting .235 with nine doubles, two triples, eight home runs and 16 walks. He's slugging .433 with an on-base percentage of .298.
• Chase Meidroth has five doubles, two home runs and 27 walks while batting .268.
• Luis Robert is batting .185 with eight doubles, eight home runs and 29 walks.

Diamondbacks vs White Sox Head to Head

• 6/24/2025: 4-1 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 8.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 6/23/2025: 10-0 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 9, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 6/16/2024: 12-5 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 8.5, Favorite Moneyline: -180, Underdog Moneyline: +152)
• 6/15/2024: 9-2 CHW (Favorite: Diamondbacks, Spread: -1.5, Total: 8.5, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 6/14/2024: 7-1 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 9, Favorite Moneyline: -196, Underdog Moneyline: +164)
• 9/28/2023: 3-1 CHW (Favorite: Diamondbacks, Spread: -1.5, Total: 9, Favorite Moneyline: -184, Underdog Moneyline: +154)
• 9/27/2023: 3-0 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 9, Favorite Moneyline: -190, Underdog Moneyline: +160)
• 9/26/2023: 15-4 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 9, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 8/28/2022: 3-2 ARI (Favorite: White Sox, Spread: -1.5, Total: 7.5, Favorite Moneyline: -184, Underdog Moneyline: +154)
• 8/27/2022: 10-5 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 8, Favorite Moneyline: -112, Underdog Moneyline: -104)

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