Diamondbacks vs Rockies Prediction, Odds, Moneyline, Spread & Over/Under for May 22

Odds updated as of 4:12 a.m.

The Friday schedule in MLB includes a matchup between the Arizona Diamondbacks and the Colorado Rockies.

We've got you covered, in terms of the most important information regarding this matchup before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Diamondbacks vs Rockies Game Info

• Arizona Diamondbacks (26-23) vs. Colorado Rockies (19-32)
• Date: Friday, May 22, 2026
• Time: 9:40 p.m. ET
• Venue: Chase Field -- Phoenix, Arizona
• Coverage: Dbacks.TV and Rockies.TV

Diamondbacks vs Rockies Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: ARI: (-184) | COL: (+154)
• Spread: ARI: -1.5 (+115) | COL: +1.5 (-138)
• Total: 8.5 -- Over: (-122) | Under: (+100)

Diamondbacks vs Rockies Probable Starting Pitchers

Probable Pitchers: Mike Soroka (Diamondbacks) - 6-2, 3.49 ERA vs Tomoyuki Sugano (Rockies) - 4-3, 4.02 ERA

The probable pitchers are Mike Soroka (6-2) for the Diamondbacks and Tomoyuki Sugano (4-3) for the Rockies. When Soroka starts, his team is 5-3-0 against the spread this season. Soroka's team has won 75% of his starts when they are favored on the moneyline (3-1). The Rockies have a 5-4-0 record against the spread in Sugano's starts. The Rockies have been the moneyline underdog in nine of Sugano's starts this season, and they went 5-4 in those games.

Diamondbacks vs Rockies Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Diamondbacks win (71.2%)

Diamondbacks vs Rockies Moneyline

• Looking at the moneyline for Diamondbacks-Rockies, Arizona is the favorite at -184, and Colorado is +154 playing on the road.

Diamondbacks vs Rockies Spread

• The Rockies are +1.5 on the spread (-138 to cover), and Arizona is +115 to cover the runline.

Diamondbacks vs Rockies Over/Under

• The Diamondbacks-Rockies contest on May 22 has been given an over/under of 8.5 runs. The over is set at -122 and the under at +100.

Bet on Arizona Diamondbacks vs. Colorado Rockies on FanDuel today!

Diamondbacks vs Rockies Betting Trends

• The Diamondbacks have come away with 13 wins in the 19 contests they have been listed as the favorites in this season.
• Arizona has played as a favorite of -184 or more just one time this year and came away with a win in that game.
• The Diamondbacks and their opponents have hit the over in 24 of their 48 games with a total set by oddsmakers this season.
• The Diamondbacks are 29-19-0 against the spread in their 48 games that had a posted line this season.
• The Rockies have been the moneyline underdog 49 total times this season. They've gone 19-30 in those games.
• Colorado has gone 8-16 in games it has played as a moneyline underdog with odds of +154 or longer (33.3%).
• In the 50 games oddsmakers have set an over/under for the Rockies, they have combined with opponents to go over the total 22 times (22-27-1).
• The Rockies have gone 27-23-0 against the spread this season.

Diamondbacks Player Leaders

• Ildemaro Vargas leads Arizona in slugging percentage (.521) thanks to 17 extra-base hits. He has a .325 batting average and an on-base percentage of .349.
• Among qualifying hitters in the majors, his batting average ranks third, his on-base percentage ranks 61st, and he is 21st in slugging.
• Corbin Carroll has 46 hits and an OBP of .390, both of which lead the Diamondbacks this season. He's batting .282 and slugging .552.
• Among all qualifying players, he ranks 36th in batting average, 14th in on-base percentage and 11th in slugging percentage.
• Carroll has picked up at least one hit in nine straight games. In his last 10 games he is hitting .343 with three doubles, two triples, two home runs, 10 walks and six RBIs.
• Ketel Marte has 44 hits this season and has a slash line of .240/.296/.415.
• Marte enters this game with five games in a row with at least one hit. In his last five games he is batting .500 with two doubles, two home runs, three walks and seven RBIs.
• Nolan Arenado is batting .273 with a .349 OBP and 25 RBI for Arizona this season.

Rockies Player Leaders

• Mickey Moniak has racked up 42 hits, a team-best for the Rockies. He's batting .280 and slugging .607 with an on-base percentage of .335.
• Including all the qualifying hitters in the majors, his batting average is 37th, his on-base percentage ranks 76th, and he is third in slugging.
• T.J. Rumfield is slugging .436 to lead his team. He has a batting average of .279 with an on-base percentage of .353.
• He is 39th in batting average, 54th in on-base percentage and 62nd in slugging percentage in the big leagues.
• Troy Johnston a has .383 on-base percentage to lead the Rockies.
• Jake McCarthy is batting .292 with seven doubles, three triples, two home runs and eight walks.

Diamondbacks vs Rockies Head to Head

• 5/21/2026: 2-1 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 9.5, Favorite Moneyline: -205, Underdog Moneyline: +172)
• 5/16/2026: 4-2 COL (Favorite: Diamondbacks, Spread: -1.5, Total: 11.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 5/15/2026: 9-1 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 11.5, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 8/17/2025: 6-5 COL (Favorite: Diamondbacks, Spread: -1.5, Total: 12, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 8/16/2025: 10-7 COL (Favorite: Diamondbacks, Spread: -1.5, Total: 11.5, Favorite Moneyline: -174, Underdog Moneyline: +146)
• 8/15/2025: 4-3 COL (Favorite: Diamondbacks, Spread: -1.5, Total: 11.5, Favorite Moneyline: -194, Underdog Moneyline: +162)
• 8/14/2025: 8-2 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 12.5, Favorite Moneyline: -174, Underdog Moneyline: +146)
• 8/10/2025: 13-6 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 9, Favorite Moneyline: -290, Underdog Moneyline: +235)
• 8/9/2025: 6-5 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 9.5, Favorite Moneyline: -225, Underdog Moneyline: +188)
• 8/8/2025: 6-1 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 9, Favorite Moneyline: -205, Underdog Moneyline: +172)

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