Diamondbacks vs Cubs Prediction, Odds, Moneyline, Spread & Over/Under for April 18

Odds updated as of 2:11 p.m.

The Arizona Diamondbacks are among the MLB squads in action on Friday, up against the Chicago Cubs.

Before you do any MLB betting on this game at FanDuel Sportsbook, here's what you need to know.

Diamondbacks vs Cubs Game Info

• Arizona Diamondbacks (12-7) vs. Chicago Cubs (12-9)
• Date: Friday, April 18, 2025
• Time: 2:20 p.m. ET
• Venue: Wrigley Field -- Chicago, Illinois
• Coverage: MARQ and ARID

Diamondbacks vs Cubs Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: ARI: (-112) | CHC: (-104)
• Spread: ARI: -1.5 (+134) | CHC: +1.5 (-162)
• Total: 11.5 -- Over: (-104) | Under: (-118)

Diamondbacks vs Cubs Probable Starting Pitchers

Probable Pitchers: Corbin Brian Burnes (Diamondbacks) - 0-1, 5.28 ERA vs Colin Rea (Cubs) - 0-0, 1.00 ERA

The Diamondbacks will give the nod to Corbin Brian Burnes (0-1) versus the Cubs and Colin Rea. Burnes and his team are 1-2-0 ATS this season when he starts. Burnes' team is 2-1 this season when he starts and they are the moneyline favorite. Rea has started just one game with a set spread, which the Cubs covered. The Cubs were the underdog on the moneyline for one Rea start this season -- they won.

Diamondbacks vs Cubs Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Diamondbacks win (52.4%)

Diamondbacks vs Cubs Moneyline

• Looking at the moneyline for Cubs-Diamondbacks, Chicago is the underdog at -104, and Arizona is -112 playing on the road.

Diamondbacks vs Cubs Spread

• The Diamondbacks are 1.5-run road favorites on the runline against the Cubs. The Diamondbacks are +134 to cover, and the Cubs are -162.

Diamondbacks vs Cubs Over/Under

• Diamondbacks versus Cubs, on April 18, has an over/under of 11.5, with the over being -104 and the under -118.

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Diamondbacks vs Cubs Betting Trends

• The Diamondbacks have been chosen as favorites in 16 games this year and have walked away with the win 10 times (62.5%) in those games.
• This season Arizona has been victorious 10 times in 16 chances when named as a favorite of at least -112 on the moneyline.
• Contests with the Diamondbacks have gone over the total set by oddsmakers in eight of 19 chances this season.
• The Diamondbacks have an against the spread record of 11-8-0 in 19 games with a line this season.
• The Cubs have won 45.5% of the games this season they were the underdog on the moneyline (5-6).
• Chicago has a 5-5 record (winning 50% of its games) when it has played as a moneyline underdog of -104 or longer.
• The Cubs have played in 21 games with an over/under set, and have combined with their opponents to go over the total 13 times (13-7-1).
• The Cubs have put together an 11-10-0 record ATS this season (covering 52.4% of the time).

Diamondbacks Player Leaders

• Corbin Carroll leads Arizona in slugging percentage (.667) and total hits (25) this season. He's batting .321 with an on-base percentage of .398.
• Among all qualifying hitters in baseball, he is 13th in batting average, 20th in on-base percentage, and fifth in slugging.
• Carroll hopes to build on a 10-game hitting streak in this matchup. During his last 10 games he is batting .386 with five doubles, a triple, three home runs, two walks and 11 RBI.
• Josh Naylor is batting .324 with six doubles, four home runs and 10 walks, while slugging .577 with an on-base percentage of .402.
• His batting average is 11th among qualified players, his on-base percentage 17th, and his slugging percentage 15th.
• Naylor enters this game looking to extend his five-game hit streak. In his last five games he is batting .333 with a double, three home runs, three walks and four RBI.
• Geraldo Perdomo leads Arizona with an OBP of .427 this season while batting .317 with 15 walks and 10 runs scored.
• Perdomo enters this game with three games in a row with at least one hit. In his last five games he is hitting .267 with a home run, eight walks and five RBI.
• Pavin Smith has three home runs, seven RBI and a batting average of .404 this season.
• Smith has safely hit in four straight games. In his last five games he is batting .438 with two doubles, two home runs, three walks and three RBI.

Cubs Player Leaders

• Kyle Tucker has accumulated an on-base percentage of .410, a slugging percentage of .578, and has 25 hits, all club-highs for the Cubs (while batting .301).
• Including all qualifying hitters, he ranks 34th in batting average, while his on-base percentage is 13th and he is 14th in slugging.
• Carson Kelly has a double, a triple, four home runs and 11 walks while batting .407. He's slugging .963 with an on-base percentage of .575.
• Pete Crow-Armstrong is hitting .259 with six doubles, a triple, three home runs and five walks.
• Nico Hoerner has two doubles, a triple and five walks while batting .313.

Diamondbacks vs Cubs Head to Head

• 3/30/2025: 10-6 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 9, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 3/29/2025: 4-3 CHC (Favorite: Diamondbacks, Spread: -1.5, Total: 8.5, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 3/28/2025: 8-1 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 9, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 3/27/2025: 10-6 CHC (Favorite: Diamondbacks, Spread: -1.5, Total: 8.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 7/21/2024: 2-1 CHC (Favorite: Cubs, Spread: -1.5, Total: 7, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 7/20/2024: 3-0 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 8.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 7/19/2024: 5-2 ARI (Favorite: Cubs, Spread: -1.5, Total: 8, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 4/17/2024: 5-3 CHC (Favorite: Diamondbacks, Spread: -1.5, Total: 9, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 4/16/2024: 12-11 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 10, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 4/15/2024: 3-2 CHC (Favorite: Diamondbacks, Spread: -1.5, Total: 8.5, Favorite Moneyline: -158, Underdog Moneyline: +134)

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