Cubs vs Reds Prediction, Odds, Moneyline, Spread & Over/Under for May 5

Odds updated as of 5:12 a.m.

In MLB action on Tuesday, the Chicago Cubs play the Cincinnati Reds.

Here's what you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Cubs vs Reds Game Info

• Chicago Cubs (23-12) vs. Cincinnati Reds (20-15)
• Date: Tuesday, May 5, 2026
• Time: 7:40 p.m. ET
• Venue: Wrigley Field -- Chicago, Illinois
• Coverage: MARQ and Reds.TV

Cubs vs Reds Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CHC: (-215) | CIN: (+180)
• Spread: CHC: -1.5 (-118) | CIN: +1.5 (-102)
• Total: 11.5 -- Over: (-110) | Under: (-110)

Cubs vs Reds Probable Starting Pitchers

Probable Pitchers: Jameson Taillon (Cubs) - 2-1, 4.41 ERA vs Andrew Abbott (Reds) - 1-2, 5.97 ERA

The probable pitchers are Jameson Taillon (2-1) for the Cubs and Andrew Abbott (1-2) for the Reds. Taillon's team is 2-4-0 against the spread this season in his starts. Taillon's team has been victorious in 66.7% of the games he's started as the moneyline favorite with a record of 2-1. The Reds have a 4-3-0 record against the spread in Abbott's starts. The Reds have been the moneyline underdog in five of Abbott's starts this season, and they went 3-2 in those games.

Cubs vs Reds Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cubs win (60.7%)

Cubs vs Reds Moneyline

• Chicago is the favorite, -215 on the moneyline, while Cincinnati is a +180 underdog on the road.

Cubs vs Reds Spread

• The Cubs are 1.5-run home favorites on the runline against the Reds. The Cubs are -118 to cover, and the Reds are -102.

Cubs vs Reds Over/Under

• A total of 11.5 runs has been set for the Cubs-Reds game on May 5, with the over available at -110 and the under at -110.

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Cubs vs Reds Betting Trends

• The Cubs have been favorites in 22 games this season and have come away with the win 15 times (68.2%) in those contests.
• Chicago has been listed as a favorite of -215 or more on two occasions this season and split those games.
• The Cubs' games have gone over the total in 22 of their 34 opportunities.
• The Cubs have posted a record of 17-17-0 against the spread this season.
• The Reds have won 14 of the 22 games they were the moneyline underdog this season (63.6%).
• Cincinnati has not yet played a game with moneyline odds of +180 or longer.
• The Reds have combined with opponents to hit the over on the total 20 times this season for a 20-12-1 record against the over/under.
• The Reds have covered 60.6% of their games this season, going 20-13-0 ATS.

Cubs Player Leaders

• Nico Hoerner has an OPS of .829, fueled by an OBP of .369 and a team-best slugging percentage of .460 this season. He has a .299 batting average.
• He ranks 28th in batting average, 40th in on-base percentage, and 48th in slugging among all qualifying hitters in MLB.
• Hoerner will look for his sixth straight game with a hit in this contest. During his last five outings he is batting .316 with three doubles and three RBIs.
• Dansby Swanson is batting .205 with two doubles, a triple, six home runs and 21 walks, while slugging .402 with an on-base percentage of .328.
• His batting average is 158th among qualified players, his on-base percentage 87th, and his slugging percentage 90th.
• Ian Happ leads Chicago with 30 hits and an OBP of .377 this season.
• Moises Ballesteros is batting .306 with a .375 OBP and 18 RBI for Chicago this season.

Reds Player Leaders

• Sal Stewart has six doubles, nine home runs and 18 walks while batting .252. He's slugging .504 with an on-base percentage of .338.
• Including all qualified hitters, he ranks 83rd in batting average, while his on-base percentage is 75th and he is 28th in slugging.
• Elly De La Cruz has racked up 39 hits with a .364 OBP while slugging .547. Those stats all pace his team. He also has a batting average of .285.
• Including all qualified hitters, he ranks 39th in batting average, 45th in on-base percentage and 14th in slugging percentage.
• Nathaniel Lowe is batting .262 with five doubles, five home runs and eight walks.
• Spencer Steer is batting .255 with six doubles, five home runs and 10 walks.

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