Angels vs White Sox Prediction, Odds, Moneyline, Spread & Over/Under for May 5

Odds updated as of 5:11 a.m.

MLB action on Tuesday includes the Los Angeles Angels playing the Chicago White Sox.

All the information you need to make smart bets on this game at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Angels vs White Sox Game Info

• Los Angeles Angels (13-23) vs. Chicago White Sox (17-18)
• Date: Tuesday, May 5, 2026
• Time: 9:38 p.m. ET
• Venue: Angel Stadium -- Anaheim, California
• Coverage: ABTV and CHSN

Angels vs White Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: LAA: (-116) | CHW: (-102)
• Spread: LAA: +1.5 (-200) | CHW: -1.5 (+164)
• Total: 9 -- Over: (-115) | Under: (-105)

Angels vs White Sox Probable Starting Pitchers

Probable Pitchers: TBA (Angels) vs Erick Fedde (White Sox) - 0-3, 0.00 ERA

Fedde (0-3) gets the start for the White Sox. As of this writing, there's been no pitching decision announced by the Angels. The White Sox have gone 2-2-0 against the spread when Fedde starts. The White Sox have a 1-3 record in Fedde's four starts this season when they were the moneyline underdog.

Angels vs White Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Angels win (57.7%)

Angels vs White Sox Moneyline

• Looking at the moneyline for Angels-White Sox, Los Angeles is the favorite at -116, and Chicago is -102 playing on the road.

Angels vs White Sox Spread

• The White Sox are 1.5-run favorites against the spread for this matchup with the Angels. The White Sox are +164 to cover, while the Angels are -200 to cover as a 1.5-run underdog on the runline.

Angels vs White Sox Over/Under

• A total of 9 runs has been set for the Angels-White Sox game on May 5, with the over available at -115 and the under at -105.

Bet on Los Angeles Angels vs. Chicago White Sox on FanDuel today!

Angels vs White Sox Betting Trends

• The Angels have been favorites in six games this season and have come away with the win two times (33.3%) in those contests.
• This season Los Angeles has come away with a win two times in five chances when named as a favorite of at least -116 on the moneyline.
• Contests with the Angels have gone over the total set by bookmakers in 16 of 35 chances this season.
• In 35 games with a line this season, the Angels have a mark of 17-18-0 against the spread.
• The White Sox have been the moneyline underdog 30 total times this season. They've gone 14-16 in those games.
• Chicago is 14-15 (winning 48.3% of its games) when playing as a moneyline underdog of -102 or longer.
• The White Sox have had an over/under set by oddsmakers 33 times, and have combined with opponents to go over the total in 17 of those games (17-16-0).
• The White Sox have covered 57.6% of their games this season, going 19-14-0 against the spread.

Angels Player Leaders

• Mike Trout has 31 hits and an OBP of .422, both of which rank first among Los Angeles hitters this season. He has a .250 batting average and a slugging percentage of .532.
• Among qualifying hitters in MLB, his batting average ranks 87th, his on-base percentage ranks fifth, and he is 20th in slugging.
• Nolan Schanuel is batting .256 with eight doubles, three home runs and 10 walks, while slugging .388 with an on-base percentage of .310.
• Among qualifying hitters, his batting average ranks him 78th, his on-base percentage 125th, and his slugging percentage 106th.
• Schanuel has picked up a hit in four straight games. In his last five games he is hitting .353 with two doubles.
• Jorge Soler has collected 27 base hits, an OBP of .326 and a slugging percentage of .453 this season.
• Zach Neto is batting .210 with a .323 OBP and 15 RBI for Los Angeles this season.

White Sox Player Leaders

• Munetaka Murakami has accumulated 30 hits with a .377 on-base percentage, leading the White Sox in both categories. He's batting .240 and slugging .584.
• Including all the qualifying players in MLB, his batting average is 104th, his on-base percentage is 34th, and he is eighth in slugging.
• Miguel Vargas is hitting .228 with four doubles, a triple, seven home runs and 24 walks. He's slugging .447 with an on-base percentage of .360.
• He is currently 126th in batting average, 52nd in on-base percentage and 55th in slugging percentage among all qualifying batters.
• Colson Montgomery is hitting .226 with five doubles, nine home runs and 14 walks.
• Chase Meidroth leads his team with a .344 slugging percentage.

Angels vs White Sox Head to Head

• 5/4/2026: 6-0 CHW (Favorite: Angels, Spread: -1.5, Total: 7.5, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 4/29/2026: 3-2 CHW (Favorite: Angels, Spread: -1.5, Total: 8.5, Favorite Moneyline: -118, Underdog Moneyline: +100)
• 4/28/2026: 5-2 CHW (Favorite: Angels, Spread: -1.5, Total: 7.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 8/3/2025: 8-5 LAA (Favorite: Angels, Spread: -1.5, Total: 9.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 8/2/2025: 1-0 CHW (Favorite: Angels, Spread: -1.5, Total: 9, Favorite Moneyline: -134, Underdog Moneyline: +116)
• 8/1/2025: 6-3 CHW (Favorite: Angels, Spread: -1.5, Total: 9, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 3/30/2025: 3-2 LAA (Favorite: Angels, Spread: -1.5, Total: 8.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 3/29/2025: 1-0 LAA (Favorite: Angels, Spread: -1.5, Total: 8, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 3/27/2025: 8-1 CHW (Favorite: Angels, Spread: -1.5, Total: 7.5, Favorite Moneyline: -164, Underdog Moneyline: +138)
• 9/26/2024: 7-0 CHW (Favorite: Angels, Spread: -1.5, Total: 7.5, Favorite Moneyline: -134, Underdog Moneyline: +114)

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