Colts vs Titans Prediction, Odds, Picks, Best Bets for NFL Week 3

The NFL slate on Sunday includes the Indianapolis Colts taking on the Tennessee Titans.

Get the latest NFL odds ahead of this game on FanDuel Sportsbook.

Colts vs Titans Prediction & Pick

All NFL win probability predictions and picks are according to numberFire.
Prediction: Colts win (54.9%)

Colts vs Titans Point Spread

The Colts are 3.5-point favorites against the Titans. The Colts are -110 to cover the spread, while the Titans are -110 to cover as a 3.5-point underdog.

Colts vs Titans Over/Under

A total of 43.5 points has been set for the Colts-Titans matchup on Sept. 21, with the over available at -106 and the under at -114.

Colts vs Titans Moneyline

Indianapolis is a -180 favorite on the moneyline, while Tennessee is a +152 underdog at home.

Colts vs Titans Betting Trends

• Indianapolis has posted two wins against the spread this year.
• One Colts game (out of two) has hit the over this year.
• The Titans have posted one win against the spread this year.
• As a 3.5-point underdog or greater, Tennessee has one win ATS (1-1) this season.
• One of the Titans' two games has gone over the point total.

Check out even more in-depth Colts vs. Titans analysis on FanDuel Research.

Colts vs Titans Odds & Spread

• All NFL odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: IND: (-180) | TEN: (+152)
• Spread: IND: -3.5 (-110) | TEN: +3.5 (-110)
• Total: 43.5 -- Over: (-106) | Under: (-114)

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