49ers vs Cardinals Prediction, Odds, Picks, Best Bets for NFL Week 3

Sunday's slate in the NFL includes a matchup between the San Francisco 49ers and the Arizona Cardinals.

All the info you need is below, in order to make a smart bet on this matchup at FanDuel Sportsbook.

49ers vs Cardinals Prediction & Pick

All NFL win probability predictions and picks are according to numberFire.
Prediction: 49ers win (50.9%)

49ers vs Cardinals Point Spread

The 49ers are 1.5-point favorites against the Cardinals. The 49ers are -105 to cover the spread, while the Cardinals are -115 to cover as a 1.5-point underdog.

49ers vs Cardinals Over/Under

A combined point total of 43.5 has been set for 49ers-Cardinals on Sept. 21, with the over at -110 and the under at -110.

49ers vs Cardinals Moneyline

The moneyline numbers for 49ers vs. Cardinals reveal San Francisco as the favorite (-120) and Arizona as the underdog (+102) on the road.

49ers vs Cardinals Betting Trends

• San Francisco has covered the spread in every game this season.
• The 49ers are unbeaten ATS (2-0) as a 1.5-point favorite or greater this year.
• One 49ers game (out of two) has hit the over this year.
• The Cardinals have posted one win against the spread this season.
• One Cardinals game (out of two) has gone over the point total this season.

Check out even more in-depth 49ers vs. Cardinals analysis on FanDuel Research.

49ers vs Cardinals Odds & Spread

• All NFL odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SF: (-120) | ARI: (+102)
• Spread: SF: -1.5 (-105) | ARI: +1.5 (-115)
• Total: 43.5 -- Over: (-110) | Under: (-110)

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