Clemson vs South Carolina Prediction, Odds, & Betting Trends for College Football Week 13 Game

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The Saturday schedule in college football includes a matchup between the Clemson Tigers and the South Carolina Gamecocks.

Before you place your bet on this game at FanDuel Sportsbook, here are the NCAA football odds and spreads you need to know.

Clemson vs South Carolina Odds & Spread

All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
Moneyline: Clemson: (-310) | South Carolina: (+245)
Spread: Clemson: -7.5 (-110) | South Carolina: +7.5 (-110)
Total: 47.5 -- Over: (-115) | Under: (-105)

Clemson's record against the spread is 5-5-0.
Clemson owns an ATS record of 3-3 as 7.5-point or greater favorites.
Out of 10 Clemson games so far this year, four have hit the over.
South Carolina's record against the spread in 2023 is 6-5-0.
South Carolina has two wins ATS (2-2) as a 7.5-point underdog or more this year.
There have been five South Carolina games (out of 11) that went over the total this year.

All college football win probability predictions and picks are according to numberFire.
Prediction: Tigers win (70.8%)

South Carolina is a 7.5-point underdog against Clemson. South Carolina is -110 to cover the spread, and Clemson is -110.

Clemson versus South Carolina, on November 25, has an over/under of 47.5, with the over being -115 and the under -105.

South Carolina is the underdog, +245 on the moneyline, while Clemson is a -310 favorite.

	Point Scored (PG)	Points Scored CFB Rank	Points Allowed (PG)	Points Allowed CFB Rank	Average Total	Games Over Current Total	Total Games
Clemson	30.4	51	21.1	29	51.3	6	11
South Carolina	27.7	73	27.3	70	54.6	7	11

Check out even more in-depth Clemson vs. South Carolina analysis on FanDuel Research.

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