Clemson vs SMU Basketball Prediction, Odds, Picks, Best Bets for February 22

The Clemson Tigers (21-5, 13-2 ACC) hope to continue a five-game road winning streak when they visit the SMU Mustangs (20-6, 11-4 ACC) on February 22, 2025.

Before you place your bet on this matchup at FanDuel Sportsbook, here are the NCAA basketball odds and spreads you need to know.

Clemson vs. SMU Game Info and Odds

• Game day: Saturday, February 22, 2025
• Game time: 4:00 PM ET
• TV channel: ACC Network
• Location: Dallas, Texas
• Arena: Moody Coliseum

Clemson vs. SMU Picks and Prediction

All college basketball win probability predictions and picks are according to numberFire.
Prediction: Clemson win (51.4%)

Before making a bet on Saturday's Clemson-SMU spread (Clemson -1.5) or over/under (145.5 points), see the betting insights and trends below.

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Clemson vs. SMU: ATS Betting Stats and Trends

• Clemson has put together a 16-10-0 record against the spread this season.
• SMU has covered 13 times in 26 matchups with a spread this season.
• Clemson covers the spread when it is a 1.5-point favorite or more 60% of the time. That's more often than SMU covers as an underdog of 1.5 or more (never covered this season).
• At home, the Tigers have a worse record against the spread (8-7-0) compared to their ATS record in road games (6-3-0).
• Against the spread, the Mustangs have had better results on the road (4-4-0) than at home (7-8-0).
• Clemson is 11-4-0 against the spread in conference play this season.
• SMU has eight wins against the spread in 15 ACC games this year.

Clemson vs. SMU: Moneyline Betting Stats

• Clemson has won in 16, or 84.2%, of the 19 contests it has been named as the moneyline favorite in this year.
• This season, the Tigers have come away with a win 16 times in 18 chances when named as a favorite of at least -128 or better on the moneyline.
• SMU has gone 1-3 in games it was listed as the moneyline underdog (winning 25% of those games).
• The Mustangs have played as a moneyline underdog of +106 or longer in just two games this season, which they lost both.
• Oddsmakers have implied with the moneyline set for this matchup that Clemson has a 56.1% chance of pulling out a win.

Clemson vs. SMU Head-to-Head Comparison

• Clemson outscores opponents by 11 points per game (scoring 77.4 per game to rank 90th in college basketball while giving up 66.4 per contest to rank 38th in college basketball) and has a +287 scoring differential overall.
• Chase Hunter leads Clemson, scoring 17 points per game (114th in the country).
• SMU's +293 scoring differential (outscoring opponents by 11.3 points per game) is a result of putting up 82.7 points per game (20th in college basketball) while allowing 71.4 per contest (170th in college basketball).
• Kevin Miller's 13.4 points per game paces SMU and ranks 461st in the country.
• The Tigers win the rebound battle by 3.3 boards on average. They collect 32.8 rebounds per game, which ranks 138th in college basketball, while their opponents grab 29.5 per contest.
• Ian Schieffelin tops the Tigers with 9.6 rebounds per game (17th in college basketball play).
• The Mustangs rank 31st in the nation at 35.6 rebounds per game. That's 6.3 more than the 29.3 their opponents average.
• Matt Cross averages 8.2 rebounds per game (57th in college basketball) to lead the Mustangs.
• Clemson ranks 44th in college basketball with 102.1 points scored per 100 possessions, and 52nd in college basketball defensively with 87.5 points conceded per 100 possessions.
• The Mustangs average 102.9 points per 100 possessions on offense (38th in college basketball), and allow 88.9 points per 100 possessions (82nd in college basketball).

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