BYU vs West Virginia Prediction, Odds, Picks, Best Bets for Week 6 2025

The BYU Cougars are among the college football squads busy on Friday, up against the West Virginia Mountaineers.

Before you place your bet on this game at FanDuel Sportsbook, here are the NCAA football odds and spreads you need to know.

BYU vs West Virginia Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: BYU: (-1000) | West Virginia: (+640)
• Spread: BYU: -18.5 (-105) | West Virginia: +18.5 (-115)
• Total: 47.5 -- Over: (-110) | Under: (-110)

BYU vs West Virginia Betting Trends

• BYU has three wins in four games against the spread this year.
• BYU is unbeaten ATS (2-0) as an 18.5-point favorite or greater this year.
• One of four BYU games have hit the over this year.
• West Virginia has won twice against the spread this season.
• West Virginia has had one game (of five) go over the total this season.

BYU vs West Virginia Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Cougars win (85.5%)

BYU vs West Virginia Point Spread

West Virginia is the underdog by 18.5 points against BYU. West Virginia is -105 to cover the spread, and BYU is -115.

BYU vs West Virginia Over/Under

The over/under for the BYU versus West Virginia matchup on Oct. 3 has been set at 47.5, with -110 odds on the over and -110 odds on the under.

BYU vs West Virginia Moneyline

The moneyline numbers for BYU vs. West Virginia reveal BYU as the favorite (-1000) and West Virginia as the underdog (+640).

BYU vs. West Virginia Points Insights

BYU vs. West Virginia Game Info

• Game day: Friday, October 3, 2025
• Game time: 10:30 p.m. ET
• TV channel: ESPN
• Location: Provo, Utah
• Stadium: LaVell Edwards Stadium

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Check out even more in-depth BYU vs. West Virginia analysis on FanDuel Research.