Brewers vs Cubs Prediction, Odds, Moneyline, Spread & Over/Under for NLDS Game 1 on Oct. 4

Odds updated as of 11:12 p.m.

The MLB schedule on Saturday includes the Milwaukee Brewers taking on the Chicago Cubs in Game 1 of the NLDS.

Before you do any MLB betting on this matchup at FanDuel Sportsbook, here's what you need to know.

Brewers vs Cubs Game Info

• Milwaukee Brewers (97-65) vs. Chicago Cubs (92-70)
• Date: Saturday, October 4, 2025
• Time: 2:08 p.m. ET
• Venue: American Family Field -- Milwaukee, Wisconsin
• Coverage: TBS and HBO Max

Brewers vs Cubs Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: MIL: (-156) | CHC: (+132)
• Spread: MIL: -1.5 (+146) | CHC: +1.5 (-176)
• Total: 7.5 -- Over: (-100) | Under: (-122)

Brewers vs Cubs Probable Starting Pitchers

Probable Pitchers: Freddy Peralta (Brewers) - 17-6, 2.70 ERA vs Matthew Boyd (Cubs) - 14-8, 3.21 ERA

The probable pitchers are Freddy Peralta (17-6, 2.70 ERA) for the Brewers and Matthew Boyd (14-8, 3.21 ERA) for the Cubs. Peralta's team is 19-14-0 against the spread in his starts this season. Peralta's team has a record of 14-8 this season when he starts and they are the favorite on the moneyline. The Cubs have gone 14-17-0 against the spread when Boyd starts. The Cubs have been the underdog on the moneyline in five of Boyd's starts this season, and they went 1-4 in those matchups.

Brewers vs Cubs Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Brewers win (60.5%)

Brewers vs Cubs Moneyline

• The Brewers vs Cubs moneyline has Milwaukee as a -156 favorite, while Chicago is a +132 underdog on the road.

Brewers vs Cubs Spread

• The Brewers are hosting the Cubs and are favored by 1.5 runs on the spread. The Brewers are +146 to cover the runline, with the Cubs being -176.

Brewers vs Cubs Over/Under

• Brewers versus Cubs, on Oct. 4, has an over/under of 7.5, with the over being -100 and the under -122.

Bet on Milwaukee Brewers vs. Chicago Cubs on FanDuel today!

Brewers vs Cubs Betting Trends

• The Brewers have been chosen as favorites in 96 games this year and have walked away with the win 60 times (62.5%) in those games.
• This season Milwaukee has come away with a win 22 times in 30 chances when named as a favorite of at least -156 on the moneyline.
• Contests with the Brewers have gone over the total set by bookmakers in 79 of 159 chances this season.
• The Brewers are 87-72-0 against the spread in their 159 games with a line set by sportsbooks this season.
• The Cubs have been the moneyline underdog 44 total times this season. They've finished 18-26 in those games.
• Chicago has a 4-3 record (winning 57.1% of its games) when playing as a moneyline underdog of +132 or longer.
• The Cubs have combined with opponents to go over the total 74 times this season for a 74-75-11 record against the over/under.
• The Cubs have a 77-83-0 record ATS this season.

Brewers Player Leaders

• Brice Turang leads Milwaukee OPS (.794) this season. He has a .288 batting average, an on-base percentage of .359, and a slugging percentage of .435.
• He ranks 16th in batting average, 20th in on-base percentage, and 71st in slugging among qualifying batters in MLB.
• Turang hopes to build on a four-game hitting streak in this matchup. In his last five games he is hitting .353 with two doubles, four walks and four RBIs.
• Christian Yelich is hitting .264 with 21 doubles, 29 home runs and 64 walks. He's slugging .452 with an on-base percentage of .343.
• Among qualifiers, he is 51st in batting average, 49th in on-base percentage and 56th in slugging percentage.
• William Contreras has collected 147 base hits, an OBP of .355 and a slugging percentage of .399 this season.
• Jackson Chourio has 148 hits, which leads Milwaukee hitters this season, while batting .270 with 60 extra-base hits.
• Chourio has hit safely in two games in a row. During his last five outings he is hitting .200 with a double, a home run, two walks and an RBI.

Cubs Player Leaders

• Kyle Tucker has put up an on-base percentage of .377, a team-high for the Cubs. He's batting .266 and slugging .464.
• Including all the qualifying hitters in the majors, he ranks 46th in batting average, seventh in on-base percentage and 44th in slugging percentage.
• Nico Hoerner leads his team with a .394 slugging percentage. He has a batting average of .297 with an on-base percentage of .345.
• Including all qualified hitters, his batting average places him eighth, his on-base percentage ranks 46th, and he is 110th in slugging.
• Pete Crow-Armstrong has 37 doubles, four triples, 31 home runs and 29 walks while batting .247.
• Seiya Suzuki is batting .245 with 31 doubles, three triples, 32 home runs and 71 walks.

Brewers vs Cubs Head to Head

• 8/21/2025: 4-1 MIL (Favorite: Cubs, Spread: -1.5, Total: 6.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 8/20/2025: 4-3 CHC (Favorite: Brewers, Spread: -1.5, Total: 6.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 8/19/2025: 4-1 CHC (Favorite: Brewers, Spread: -1.5, Total: 6.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 8/19/2025: 6-4 CHC (Favorite: Cubs, Spread: -1.5, Total: 6.5, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 8/18/2025: 7-0 MIL (Favorite: Cubs, Spread: -1.5, Total: 8, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 7/30/2025: 10-3 CHC (Favorite: Brewers, Spread: -1.5, Total: 7, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 7/29/2025: 9-3 MIL (Favorite: Brewers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 7/28/2025: 8-4 MIL (Favorite: Cubs, Spread: -1.5, Total: 8, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 6/19/2025: 8-7 MIL (Favorite: Cubs, Spread: -1.5, Total: 8.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 6/17/2025: 5-3 CHC (Favorite: Cubs, Spread: -1.5, Total: 9.5, Favorite Moneyline: -156, Underdog Moneyline: +132)

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