Brewers vs Cubs Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 20

Odds updated as of 8:11 a.m.

Wednesday's slate in the MLB includes a matchup between the Milwaukee Brewers and the Chicago Cubs.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the vital information about this game.

Brewers vs Cubs Game Info

• Milwaukee Brewers (79-47) vs. Chicago Cubs (72-54)
• Date: Wednesday, August 20, 2025
• Time: 8:05 p.m. ET
• Venue: Wrigley Field -- Chicago, Illinois
• Coverage: MARQ and FDSWI

Brewers vs Cubs Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: MIL: (-116) | CHC: (-102)
• Spread: MIL: -1.5 (+162) | CHC: +1.5 (-196)
• Total: 6.5 -- Over: (-132) | Under: (+108)

Brewers vs Cubs Probable Starting Pitchers

Probable Pitchers: Jacob Misiorowski (Brewers) - 4-1, 3.89 ERA vs Colin Rea (Cubs) - 9-5, 3.99 ERA

The Brewers will give the nod to Jacob Misiorowski (4-1, 3.89 ERA), who is eyeing win No. 5 on the season, and the Cubs will turn to Colin Rea (9-5, 3.99 ERA). Misiorowski's team is 7-1-0 against the spread this season in his starts. Misiorowski's team is 1-1 this season when he starts and they're favored on the moneyline. The Cubs have a 12-8-0 ATS record in Rea's 20 starts with a set spread. The Cubs have a 4-2 record in Rea's six starts this season when they were the underdog on the moneyline.

Brewers vs Cubs Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Brewers win (51.1%)

Brewers vs Cubs Moneyline

• The Brewers vs Cubs moneyline has Milwaukee as a -116 favorite, while Chicago is a -102 underdog at home.

Brewers vs Cubs Spread

• The Cubs are at +1.5 on the runline against the Brewers. The Cubs are -196 to cover the spread, and the Brewers are +162.

Brewers vs Cubs Over/Under

• The over/under for Brewers-Cubs on Aug. 20 is 6.5. The over is -132, and the under is +108.

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Brewers vs Cubs Betting Trends

• The Brewers have come away with 46 wins in the 66 contests they have been listed as the favorites in this season.
• Milwaukee has a record of 42-18 when favored by -116 or more this year.
• The Brewers and their opponents have hit the over in 60 of their 124 games with a total set by oddsmakers this season.
• The Brewers have an against the spread mark of 73-51-0 in 124 games with a line this season.
• The Cubs have compiled a 15-22 record in games they were listed as the moneyline underdog (winning 40.5% of those games).
• When it has played as a moneyline underdog with odds of -102 or longer, Chicago has a 13-17 record (winning 43.3% of its games).
• The Cubs have played in 122 games with a set over/under, and have combined with their opponents to go over the total 57 times (57-57-8).
• The Cubs have a 58-64-0 record ATS this season.

Brewers Player Leaders

• Christian Yelich is batting .265 with 14 doubles, 26 home runs and 50 walks. He has an on-base percentage of .344 while slugging .467.
• Among all qualifying hitters in MLB, he ranks 56th in batting average, 50th in on-base percentage, and 46th in slugging.
• Yelich hopes to build on a two-game hitting streak in this matchup. In his last five games he is hitting .105 with a home run, three walks and an RBI.
• William Contreras has 22 doubles, 13 home runs and 70 walks. He's batting .260 and slugging .395 with an on-base percentage of .359.
• His batting average is 73rd among qualified players, his on-base percentage 27th, and his slugging percentage 116th.
• Contreras takes a two-game streak with at least one hit into this matchup. In his last five games he is hitting .238 with a home run, three walks and two RBIs.
• Brice Turang has an OPS of .759, fueled by an OBP of .343 and a team-best slugging percentage of .415 this season.
• Turang enters this game with three games in a row with at least one hit. In his last five games he is hitting .333 with a double, a home run, a walk and four RBIs.
• Sal Frelick leads Milwaukee in OBP (.363) this season, fueled by 121 hits.
• Frelick has hit safely in three games in a row. In his last five games he is hitting .333 with a double, four walks and two RBIs.

Cubs Player Leaders

• Kyle Tucker has racked up a team-high .374 on-base percentage. He's batting .261 and slugging .447.
• Including all qualifying hitters in MLB, he is 70th in batting average, 12th in on-base percentage and 66th in slugging percentage.
• Pete Crow-Armstrong has racked up 123 hits to lead his team. He has a batting average of .259 while slugging .516 with an on-base percentage of .299.
• He is currently 78th in batting average, 136th in on-base percentage and 14th in slugging percentage among all qualifying hitters.
• Seiya Suzuki has 27 doubles, three triples, 27 home runs and 53 walks while hitting .247.
• Nico Hoerner leads his team with a .374 slugging percentage.

Brewers vs Cubs Head to Head

• 8/19/2025: 4-1 CHC (Favorite: Brewers, Spread: -1.5, Total: 6.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 8/19/2025: 6-4 CHC (Favorite: Cubs, Spread: -1.5, Total: 6.5, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 8/18/2025: 7-0 MIL (Favorite: Cubs, Spread: -1.5, Total: 8, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 7/30/2025: 10-3 CHC (Favorite: Brewers, Spread: -1.5, Total: 7, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 7/29/2025: 9-3 MIL (Favorite: Brewers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 7/28/2025: 8-4 MIL (Favorite: Cubs, Spread: -1.5, Total: 8, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 6/19/2025: 8-7 MIL (Favorite: Cubs, Spread: -1.5, Total: 8.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 6/17/2025: 5-3 CHC (Favorite: Cubs, Spread: -1.5, Total: 9.5, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 5/4/2025: 4-0 MIL (Favorite: Brewers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 5/3/2025: 6-2 CHC (Favorite: Cubs, Spread: -1.5, Total: 8.5, Favorite Moneyline: -112, Underdog Moneyline: -104)

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