Angels vs Royals Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 24

Odds updated as of 6:12 a.m.

The Los Angeles Angels are among the MLB squads playing on Wednesday, up against the Kansas City Royals.

We've got you covered, in terms of the most important information about this game before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Angels vs Royals Game Info

• Los Angeles Angels (70-87) vs. Kansas City Royals (79-78)
• Date: Wednesday, September 24, 2025
• Time: 9:38 p.m. ET
• Venue: Angel Stadium -- Anaheim, California
• Coverage: FDSW and FDSKC

Angels vs Royals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: LAA: (-124) | KC: (+106)
• Spread: LAA: -1.5 (+155) | KC: +1.5 (-188)
• Total: 8.5 -- Over: (-100) | Under: (-122)

Angels vs Royals Probable Starting Pitchers

Probable Pitchers: Yusei Kikuchi (Angels) - 6-11, 4.05 ERA vs Stephen Kolek (Royals) - 5-6, 3.54 ERA

The probable starters are Yusei Kikuchi (6-11) for the Angels and Stephen Kolek (5-6) for the Royals. Kikuchi and his team have a record of 17-15-0 against the spread when he starts. When Kikuchi starts a game and his team is the favorite on the moneyline, they have a record of 8-3. The Royals have a 12-6-0 record against the spread in Kolek's starts. The Royals are 4-7 in Kolek's 11 starts this season that they were the underdog on the moneyline.

Angels vs Royals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Royals win (52.6%)

Angels vs Royals Moneyline

• Looking at the moneyline for Angels-Royals, Los Angeles is the favorite at -124, and Kansas City is +106 playing on the road.

Angels vs Royals Spread

• The Royals are at the Angels, and are +1.5 on the runline. The Royals are +155 to cover the spread, and the Angels are -188.

Angels vs Royals Over/Under

• The over/under for the Angels versus Royals contest on Sept. 24 has been set at 8.5, with -100 odds on the over and -122 odds on the under.

Bet on Los Angeles Angels vs. Kansas City Royals on FanDuel today!

Angels vs Royals Betting Trends

• The Angels have won in 18, or 50%, of the 36 contests they have been named as odds-on favorites in this year.
• This season Los Angeles has come away with a win 14 times in 27 chances when named as a favorite of at least -124 on the moneyline.
• The Angels and their opponents have gone over in 83 of their 155 games with a total set by sportsbooks this season.
• In 155 games with a line this season, the Angels have a mark of 81-74-0 against the spread.
• The Royals have compiled a 41-50 record in games they were the underdog on the moneyline (winning 45.1% of those games).
• In games it has played as a moneyline underdog with odds of +106 or longer, Kansas City has a 25-36 record (winning 41% of its games).
• The Royals have had an over/under set by bookmakers 155 times, and have combined with opponents to go over the total in 68 of those games (68-85-2).
• The Royals are 76-79-0 ATS this season.

Angels Player Leaders

• Taylor Ward leads Los Angeles with a slugging percentage of .474, fueled by 68 extra-base hits. He has a .228 batting average and an on-base percentage of .315.
• He ranks 136th in batting average, 100th in on-base percentage, and 35th in slugging among qualifying hitters in the majors.
• Ward hopes to build on a six-game hitting streak in this matchup. In his last 10 outings he is hitting .256 with five home runs and five RBIs.
• Jo Adell has 120 hits, which leads Los Angeles batters this season. He's batting .237 with 54 extra-base hits. He's also slugging .488 with an on-base percentage of .296.
• He ranks 118th in batting average, 125th in on-base percentage and 22nd in slugging in MLB.
• Adell takes a two-game streak with at least one hit into this one. During his last five outings he is hitting .222 with two walks and an RBI.
• Nolan Schanuel leads Los Angeles with an OBP of .357 this season while batting .268 with 58 walks and 63 runs scored.
• Schanuel has logged a hit or more in four straight games. In his last five games he is batting .294 with a double, a home run, two walks and three RBIs.
• Mike Trout has 22 home runs, 59 RBI and a batting average of .227 this season.

Royals Player Leaders

• Bobby Witt Jr. has 176 hits with a .502 slugging percentage, both team-high numbers for the Royals. He's batting .293 and with an on-base percentage of .351.
• Including all the qualifying hitters in the big leagues, he is 11th in batting average, 35th in on-base percentage and 16th in slugging percentage.
• Witt heads into this matchup on a four-game hitting streak. During his last five outings he is hitting .304 with two doubles, a home run and four RBIs.
• Maikel Garcia paces his team with a .354 OBP. He has a batting average of .288 while slugging .455.
• He is 16th in batting average, 32nd in on-base percentage and 56th in slugging percentage in MLB.
• Vinnie Pasquantino is batting .269 with 31 doubles, a triple, 31 home runs and 48 walks.
• Salvador Perez is batting .242 with 34 doubles, 30 home runs and 26 walks.

Angels vs Royals Head to Head

• 9/23/2025: 8-4 KC (Favorite: Royals, Spread: -1.5, Total: 9, Favorite Moneyline: -166, Underdog Moneyline: +140)
• 9/4/2025: 4-3 KC (Favorite: Royals, Spread: -1.5, Total: 9, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 9/3/2025: 4-3 LAA (Favorite: Royals, Spread: -1.5, Total: 9, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 9/2/2025: 5-1 LAA (Favorite: Royals, Spread: -1.5, Total: 9, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 8/21/2024: 3-0 KC (Favorite: Royals, Spread: -1.5, Total: 9, Favorite Moneyline: -180, Underdog Moneyline: +152)
• 8/20/2024: 9-5 LAA (Favorite: Royals, Spread: -1.5, Total: 8, Favorite Moneyline: -200, Underdog Moneyline: +168)
• 8/19/2024: 5-3 KC (Favorite: Royals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -240, Underdog Moneyline: +198)
• 5/12/2024: 4-2 KC (Favorite: Angels, Spread: -1.5, Total: 8, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 5/11/2024: 9-3 LAA (Favorite: Royals, Spread: -1.5, Total: 8, Favorite Moneyline: -164, Underdog Moneyline: +138)
• 5/10/2024: 2-1 KC (Favorite: Royals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -122, Underdog Moneyline: +104)

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