Yankees vs Guardians Prediction, Odds, Moneyline, Spread & Over/Under for June 4

Odds updated as of 9:11 p.m.

MLB action on Thursday includes the New York Yankees playing the Cleveland Guardians.

Here's everything you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Yankees vs Guardians Game Info

• New York Yankees (36-24) vs. Cleveland Guardians (35-27)
• Date: Thursday, June 4, 2026
• Time: 1:35 p.m. ET
• Venue: Yankee Stadium -- The Bronx, New York
• Coverage: YES and CleGuardians.TV

Yankees vs Guardians Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: NYY: (-162) | CLE: (+136)
• Spread: NYY: -1.5 (+128) | CLE: +1.5 (-154)
• Total: 8.5 -- Over: (-112) | Under: (-108)

Yankees vs Guardians Probable Starting Pitchers

Probable Pitchers: Carlos Rodon (Yankees) - 1-2, 3.32 ERA vs Slade Cecconi (Guardians) - 3-5, 5.25 ERA

The Yankees will call on Carlos Rodon (1-2) against the Guardians and Slade Cecconi (3-5). Rodon's team is 1-3-0 against the spread this season in his starts. Rodon's team has been victorious in 33.3% of the games he's started as the moneyline favorite with a record of 1-2. The Guardians have a 3-7-0 record against the spread in Cecconi's starts. The Guardians have a 2-5 record in Cecconi's seven starts this season when they were the underdog on the moneyline.

Yankees vs Guardians Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Yankees win (65.7%)

Yankees vs Guardians Moneyline

• New York is the favorite, -162 on the moneyline, while Cleveland is a +136 underdog on the road.

Yankees vs Guardians Spread

• The Yankees are hosting the Guardians and are favored by 1.5 runs (+128 to cover) on the runline. Cleveland is -154 to cover.

Yankees vs Guardians Over/Under

• A total of 8.5 runs has been set for the Yankees-Guardians game on June 4, with the over available at -112 and the under at -108.

Bet on New York Yankees vs. Cleveland Guardians on FanDuel today!

Yankees vs Guardians Betting Trends

• The Yankees have been victorious in 33, or 62.3%, of the 53 contests they have been chosen as favorites in this season.
• New York has a record of 15-8 in contests when bookmakers favor them by -162 or more on the moneyline.
• The Yankees and their opponents have hit the over in 26 of their 57 games with a total set by oddsmakers this season.
• The Yankees have an against the spread mark of 29-28-0 in 57 games with a line this season.
• The Guardians have gone 14-10 in games they were listed as the moneyline underdog (winning 58.3% of those games).
• Cleveland has a record of 6-3 when playing as a moneyline underdog with odds of +136 or longer (66.7%).
• The Guardians have played in 58 games with an over/under set, and have combined with opponents to go over the total 30 times (30-28-0).
• The Guardians have a 29-29-0 record against the spread this season (covering 50% of the time).

Yankees Player Leaders

• Ben Rice leads New York with 61 hits and an OBP of .397, plus a team-best slugging percentage of .650. He's batting .305.
• Among qualifying batters in MLB, his batting average ranks 12th, his on-base percentage ranks ninth, and he is first in slugging.
• Rice will look for his seventh straight game with a hit in this contest. During his last 10 outings he is batting .366 with four doubles, two triples, a home run, five walks and 11 RBIs.
• Cody Bellinger has 13 doubles, three triples, eight home runs and 38 walks. He's batting .274 and slugging .474 with an on-base percentage of .379.
• Among qualifying hitters, he ranks 48th in batting average, 23rd in on-base percentage and 39th in slugging percentage.
• Bellinger enters this game looking to extend his two-game hit streak. In his last five games he is hitting .250 with four walks and two RBIs.
• Aaron Judge is batting .248 with a .533 slugging percentage and 38 RBI this year.
• Trent Grisham has been key for New York with 40 hits, an OBP of .329 plus a slugging percentage of .377.
• Grisham heads into this game on a two-game hitting streak. In his last five games he is hitting .294 with four walks and two RBIs.

Guardians Player Leaders

• Jose Ramirez is batting .236 with 17 doubles, eight home runs and 39 walks. He's slugging .415 with an on-base percentage of .346.
• He is 111th in batting average, 60th in on-base percentage and 84th in slugging percentage among all qualifying hitters in the majors.
• Ramirez brings a four-game hitting streak into this game. During his last five outings he is hitting .316 with five doubles, two walks and five RBIs.
• Chase DeLauter has 11 doubles, a triple, seven home runs and 26 walks while batting .263. He's slugging .426 with an on-base percentage of .342.
• His batting average ranks 59th among all qualified players, his on-base percentage is 68th, and he is 74th in slugging.
• Brayan Rocchio has a team-high OBP (.376) and slugging percentage (.416).
• Angel Martinez's 46 hits pace his team.

Yankees vs Guardians Head to Head

• 6/2/2026: 9-4 CLE (Favorite: Yankees, Spread: -1.5, Total: 7.5, Favorite Moneyline: -220, Underdog Moneyline: +184)
• 6/5/2025: 4-0 NYY (Favorite: Yankees, Spread: -1.5, Total: 8.5, Favorite Moneyline: -275, Underdog Moneyline: +225)
• 6/4/2025: 4-0 CLE (Favorite: Yankees, Spread: -1.5, Total: 9, Favorite Moneyline: -196, Underdog Moneyline: +164)
• 6/3/2025: 3-2 NYY (Favorite: Yankees, Spread: -1.5, Total: 8, Favorite Moneyline: -200, Underdog Moneyline: +168)
• 4/23/2025: 5-1 NYY (Favorite: Yankees, Spread: -1.5, Total: 8.5, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 4/22/2025: 3-2 CLE (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 4/21/2025: 6-4 CLE (Favorite: Yankees, Spread: -1.5, Total: 8.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 10/19/2024: 5-2 NYY (Favorite: Yankees, Spread: -1.5, Total: 7.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 10/18/2024: 8-6 NYY (Favorite: Yankees, Spread: -1.5, Total: 7.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 10/17/2024: 7-5 CLE (Favorite: Guardians, Spread: -1.5, Total: 7, Favorite Moneyline: -108, Underdog Moneyline: -108)

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