Yankees vs Cardinals Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 16

Odds updated as of 12:15 p.m.

Saturday's slate in the MLB includes a matchup between the New York Yankees and the St. Louis Cardinals.

We've got you covered, in terms of the vital information regarding this matchup before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Yankees vs Cardinals Game Info

• New York Yankees (65-57) vs. St. Louis Cardinals (61-62)
• Date: Saturday, August 16, 2025
• Time: 7:15 p.m. ET
• Venue: Busch Stadium -- St. Louis, Missouri
• Coverage: FOX

Yankees vs Cardinals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: NYY: (-146) | STL: (+124)
• Spread: NYY: -1.5 (+115) | STL: +1.5 (-138)
• Total: 9 -- Over: (-102) | Under: (-120)

Yankees vs Cardinals Probable Starting Pitchers

Probable Pitchers: Max Fried (Yankees) - 12-5, 2.94 ERA vs Sonny Gray (Cardinals) - 11-5, 4.06 ERA

The Yankees will give the nod to Max Fried (12-5) versus the Cardinals and Sonny Gray (11-5). Fried and his team are 13-11-0 ATS this season when he starts. Fried's team has been victorious in 62.5% of the games he's started as the moneyline favorite with a record of 15-9. The Cardinals have gone 12-10-0 against the spread when Gray starts. The Cardinals have a 5-2 record in Gray's seven starts this season when they were the underdog on the moneyline.

Yankees vs Cardinals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cardinals win (50.7%)

Yankees vs Cardinals Moneyline

• New York is a -146 favorite on the moneyline, while St. Louis is a +124 underdog at home.

Yankees vs Cardinals Spread

• The Cardinals are +1.5 on the spread (-138 to cover), and New York is +115 to cover the runline.

Yankees vs Cardinals Over/Under

• Yankees versus Cardinals, on Aug. 16, has an over/under of 9, with the over being -102 and the under -120.

Bet on New York Yankees vs. St. Louis Cardinals on FanDuel today!

Yankees vs Cardinals Betting Trends

• The Yankees have been victorious in 57, or 56.4%, of the 101 contests they have been chosen as favorites in this season.
• This year New York has won 42 of 65 games when listed as at least -146 on the moneyline.
• The Yankees and their opponents have gone over the total this season in 54 of their 120 opportunities.
• In 120 games with a line this season, the Yankees have a mark of 51-69-0 against the spread.
• The Cardinals have been the moneyline underdog 63 total times this season. They've finished 31-32 in those games.
• When playing as a moneyline underdog with odds of +124 or longer, St. Louis has a record of 10-14 (41.7%).
• The Cardinals have combined with opponents to go over the total 59 times this season for a 59-54-5 record against the over/under.
• The Cardinals are 61-57-0 ATS this season.

Yankees Player Leaders

• Aaron Judge has 134 hits and an OBP of .442 to go with a slugging percentage of .680. All three of those stats are best among New York hitters this season. He has a .330 batting average, as well.
• Among all qualifying hitters in the majors, he is first in batting average, first in on-base percentage, and first in slugging.
• Cody Bellinger has 20 doubles, five triples, 22 home runs and 37 walks. He's batting .267 and slugging .485 with an on-base percentage of .322.
• His batting average ranks 53rd among qualified players, his on-base percentage 94th, and his slugging percentage 28th.
• Anthony Volpe is batting .217 with a .418 slugging percentage and 65 RBI this year.
• Trent Grisham is batting .242 with a .347 OBP and 46 RBI for New York this season.

Cardinals Player Leaders

• Brendan Donovan has put up a team-best OBP (.348) and slugging percentage (.402). He's batting .279.
• Including all qualified hitters in the majors, he is 29th in batting average, 46th in on-base percentage and 104th in slugging percentage.
• Alec Burleson has collected 107 hits to pace his team. He has a batting average of .279 while slugging .446 with an on-base percentage of .333.
• His batting average ranks 29th among all qualified players, his on-base percentage is 68th, and he is 67th in slugging.
• Willson Contreras is batting .255 with 29 doubles, 16 home runs and 39 walks.
• Masyn Winn is batting .265 with 26 doubles, eight home runs and 31 walks.

Yankees vs Cardinals Head to Head

• 8/15/2025: 4-3 NYY (Favorite: Yankees, Spread: -1.5, Total: 9, Favorite Moneyline: -146, Underdog Moneyline: +124)
• 9/1/2024: 14-7 STL (Favorite: Yankees, Spread: -1.5, Total: 9.5, Favorite Moneyline: -235, Underdog Moneyline: +194)
• 8/31/2024: 6-5 STL (Favorite: Yankees, Spread: -1.5, Total: 9.5, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 8/30/2024: 6-3 NYY (Favorite: Yankees, Spread: -1.5, Total: 8.5, Favorite Moneyline: -184, Underdog Moneyline: +154)
• 7/2/2023: 5-1 STL (Favorite: Cardinals, Spread: -1.5, Total: 8, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 7/1/2023: 6-2 NYY (Favorite: Cardinals, Spread: -1.5, Total: 9.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 7/1/2023: 11-4 STL (Favorite: Cardinals, Spread: -1.5, Total: 9, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 8/7/2022: 12-9 STL (Favorite: Yankees, Spread: -1.5, Total: 8, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 8/6/2022: 1-0 STL (Favorite: Cardinals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 8/5/2022: 4-3 STL (Favorite: Yankees, Spread: -1.5, Total: 8.5, Favorite Moneyline: -164, Underdog Moneyline: +138)

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