White Sox vs Tigers Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 19

Odds updated as of 10:11 p.m.

Saturday's slate in the MLB includes a matchup between the Chicago White Sox and the Detroit Tigers.

All the info you need to make smart wagers on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

White Sox vs Tigers Game Info

• Chicago White Sox (78-75) vs. Detroit Tigers (72-81)
• Date: Saturday, September 19, 2026
• Time: 2:10 p.m. ET
• Venue: Rate Field -- Chicago, Illinois
• Coverage: CHSN and DSN

White Sox vs Tigers Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CHW: (-134) | DET: (+116)
• Spread: CHW: -1.5 (+158) | DET: +1.5 (-194)
• Total: 8.5 -- Over: (+108) | Under: (-132)

White Sox vs Tigers Probable Starting Pitchers

Probable Pitchers: Sean Burke (White Sox) - 9-7, 3.47 ERA vs Jackson Jobe (Tigers) - 2-2, 3.89 ERA

This contest's pitching matchup is set, as the White Sox will send Sean Burke (9-7) to the mound, while Jackson Jobe (2-2) will answer the bell for the Tigers. When Burke starts, his team is 13-12-0 against the spread this season. Burke's team has a record of 7-3 this season when he starts and they are the favorite on the moneyline. The Tigers have a 5-2-0 record against the spread in Jobe's starts. The Tigers are 1-3 in Jobe's four starts this season that they were the underdog on the moneyline.

White Sox vs Tigers Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Tigers win (50.4%)

White Sox vs Tigers Moneyline

• Detroit is the underdog, +116 on the moneyline, while Chicago is a -134 favorite at home.

White Sox vs Tigers Spread

• The Tigers are at the White Sox, and are +1.5 on the runline. The Tigers are +158 to cover the spread, and the White Sox are -194.

White Sox vs Tigers Over/Under

• The White Sox-Tigers contest on Sept. 19 has been given an over/under of 8.5 runs. The over is set at +108 and the under at -132.

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White Sox vs Tigers Betting Trends

• The White Sox have been victorious in 20, or 54.1%, of the 37 contests they have been chosen as favorites in this season.
• Chicago has a record of 5-5 when favored by -134 or more this year.
• The White Sox's games have gone over the total in 83 of their 150 opportunities.
• The White Sox are 84-66-0 against the spread in their 150 games with a line set by sportsbooks this season.
• The Tigers have been the underdog on the moneyline 64 total times this season. They've gone 28-36 in those games.
• When playing as a moneyline underdog with odds of +116 or longer, Detroit has a record of 9-13 (40.9%).
• The Tigers have played in 147 games with a set over/under, and have combined with opponents to go over the total 64 times (64-80-3).
• The Tigers have put together a 76-71-0 record ATS this season.

White Sox Player Leaders

• Miguel Vargas leads Chicago with 139 hits, batting .248 this season with 62 extra-base hits. He has an on-base percentage of .356 and a slugging percentage of .471.
• Among qualifying hitters in the majors, his batting average ranks 82nd, his on-base percentage ranks 35th, and he is 30th in slugging.
• Chase Meidroth has hit 14 homers this season while driving in 56 runs. He's batting .271 this season and slugging .401 with an on-base percentage of .345.
• Among all qualified, he is 40th in batting average, 49th in on-base percentage and 89th in slugging percentage.
• Meidroth brings a four-game streak with at least one hit into this one. In his last five games he is batting .350 with two doubles, a walk and three RBIs.
• Sam Antonacci leads Chicago in OBP (.367) this season, fueled by 122 hits.
• Tristan Peters has been key for Chicago with 114 hits, an OBP of .343 plus a slugging percentage of .452.

Tigers Player Leaders

• Kevin McGonigle has an on-base percentage of .377 and a slugging percentage of .425. Both lead the Tigers. He's batting .275.
• Including all qualified hitters in the majors, his batting average puts him 35th, his on-base percentage ranks 10th, and he is 67th in slugging.
• Riley Greene has 137 hits to lead his team. He has a batting average of .284 while slugging .478 with an on-base percentage of .370.
• Including all qualified players, his batting average places him 16th, his on-base percentage ranks 15th, and he is 27th in slugging.
• Dillon Dingler is batting .242 with 26 doubles, two triples, 27 home runs and 32 walks.
• Spencer Torkelson is hitting .227 with 26 doubles, 24 home runs and 65 walks.

White Sox vs Tigers Head to Head

• 9/17/2026: 3-1 CHW (Favorite: White Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 8/16/2026: 7-5 CHW (Favorite: Tigers, Spread: -1.5, Total: 8, Favorite Moneyline: -110, Underdog Moneyline: +102)
• 8/15/2026: 4-3 CHW (Favorite: Tigers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -136, Underdog Moneyline: +126)
• 8/14/2026: 9-5 CHW (Favorite: Tigers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -128, Underdog Moneyline: +120)
• 6/21/2026: 5-4 DET (Favorite: Tigers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 6/20/2026: 4-1 DET (Favorite: Tigers, Spread: -1.5, Total: 9, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 6/19/2026: 4-3 DET (Favorite: Tigers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -210, Underdog Moneyline: +176)
• 5/31/2026: 2-1 CHW (Favorite: White Sox, Spread: -1.5, Total: 8, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 5/30/2026: 7-1 CHW (Favorite: Tigers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 5/29/2026: 4-3 CHW (Favorite: White Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -108, Underdog Moneyline: -108)

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