White Sox vs Tigers Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 18

Odds updated as of 2:12 a.m.

The Chicago White Sox versus the Detroit Tigers is on the MLB schedule for Friday.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the vital info regarding this game.

White Sox vs Tigers Game Info

• Chicago White Sox (78-75) vs. Detroit Tigers (72-81)
• Date: Friday, September 18, 2026
• Time: 7:40 p.m. ET
• Venue: Rate Field -- Chicago, Illinois
• Coverage: CHSN and DSN

White Sox vs Tigers Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CHW: (-130) | DET: (+110)
• Spread: CHW: -1.5 (+164) | DET: +1.5 (-200)
• Total: 8.5 -- Over: (-106) | Under: (-114)

White Sox vs Tigers Probable Starting Pitchers

Probable Pitchers: David Sandlin (White Sox) - 2-2, 5.64 ERA vs Andrew Sears (Tigers) - 0-1, 5.40 ERA

The White Sox will give the nod to David Sandlin (2-2) against the Tigers and Andrew Sears (0-1). When Sandlin starts, his team is 2-2-0 against the spread this season. Sandlin's team is 1-1 this season when he starts and they're favored on the moneyline. Sears has started only one game with a set spread, which the Tigers covered. The Tigers have always been the moneyline underdog when Sears starts this season.

White Sox vs Tigers Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: White Sox win (51.6%)

White Sox vs Tigers Moneyline

• The moneyline numbers for White Sox vs. Tigers reveal Chicago as the favorite (-130) and Detroit as the underdog (+110) on the road.

White Sox vs Tigers Spread

• The White Sox are favored by 1.5 runs at home versus the Tigers. The White Sox are +164 to cover the spread, while the Tigers are -200.

White Sox vs Tigers Over/Under

• White Sox versus Tigers on Sept. 18 has an over/under of 8.5 runs, with the odds on the over -106 and the under set at -114.

Bet on Chicago White Sox vs. Detroit Tigers on FanDuel today!

White Sox vs Tigers Betting Trends

• The White Sox have been favorites in 37 games this season and have come away with the win 20 times (54.1%) in those contests.
• This season Chicago has come away with a win seven times in 13 chances when named as a favorite of at least -130 on the moneyline.
• Contests with the White Sox have gone over the total set by bookmakers in 83 of 150 chances this season.
• The White Sox are 84-66-0 against the spread in their 150 games that had a posted line this season.
• The Tigers have won 43.8% of the games this season they were the underdog on the moneyline (28-36).
• Detroit has a 12-17 record (winning 41.4% of its games) when playing as a moneyline underdog of +110 or longer.
• The Tigers have played in 147 games with an over/under set, and have combined with opponents to go over the total 64 times (64-80-3).
• The Tigers have a 76-71-0 record against the spread this season (covering 51.7% of the time).

White Sox Player Leaders

• Miguel Vargas has 139 hits, which ranks first among Chicago hitters this season, while batting .248 with 62 extra-base hits. He has an on-base percentage of .356 and a slugging percentage of .471.
• Among qualified hitters in MLB, his batting average ranks 82nd, his on-base percentage ranks 35th, and he is 30th in slugging.
• Chase Meidroth has hit 14 homers this season while driving in 56 runs. He's batting .271 this season and slugging .401 with an on-base percentage of .345.
• He is 40th in batting average, 49th in on-base percentage and 89th in slugging in the major leagues.
• Meidroth takes a four-game streak with at least one hit into this matchup. In his last five games he is hitting .350 with two doubles, a walk and three RBIs.
• Sam Antonacci leads Chicago in OBP (.367) this season, fueled by 122 hits.
• Tristan Peters has been key for Chicago with 114 hits, an OBP of .343 plus a slugging percentage of .452.

Tigers Player Leaders

• Kevin McGonigle has accumulated a team-high OBP (.377) and slugging percentage (.425). He's batting .275.
• Including all qualifying hitters, he ranks 35th in batting average, while his on-base percentage is 10th and he is 67th in slugging.
• Riley Greene paces his team with 137 hits. He has a batting average of .284 while slugging .478 with an on-base percentage of .370.
• He is currently 16th in batting average, 15th in on-base percentage and 27th in slugging percentage among all qualified hitters.
• Dillon Dingler is hitting .242 with 26 doubles, two triples, 27 home runs and 32 walks.
• Spencer Torkelson is hitting .227 with 26 doubles, 24 home runs and 65 walks.

White Sox vs Tigers Head to Head

• 9/17/2026: 3-1 CHW (Favorite: White Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 8/16/2026: 7-5 CHW (Favorite: Tigers, Spread: -1.5, Total: 8, Favorite Moneyline: -110, Underdog Moneyline: +102)
• 8/15/2026: 4-3 CHW (Favorite: Tigers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -136, Underdog Moneyline: +126)
• 8/14/2026: 9-5 CHW (Favorite: Tigers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -128, Underdog Moneyline: +120)
• 6/21/2026: 5-4 DET (Favorite: Tigers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 6/20/2026: 4-1 DET (Favorite: Tigers, Spread: -1.5, Total: 9, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 6/19/2026: 4-3 DET (Favorite: Tigers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -210, Underdog Moneyline: +176)
• 5/31/2026: 2-1 CHW (Favorite: White Sox, Spread: -1.5, Total: 8, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 5/30/2026: 7-1 CHW (Favorite: Tigers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 5/29/2026: 4-3 CHW (Favorite: White Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -108, Underdog Moneyline: -108)

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!