White Sox vs Rockies Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 26

Odds updated as of 2:11 a.m.

In MLB action on Saturday, the Chicago White Sox take on the Colorado Rockies.

We've got you covered, in terms of the most important info regarding this matchup before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

White Sox vs Rockies Game Info

• Chicago White Sox (83-77) vs. Colorado Rockies (57-103)
• Date: Saturday, September 26, 2026
• Time: 7:10 p.m. ET
• Venue: Rate Field -- Chicago, Illinois
• Coverage: CHSN and Rockies.TV

White Sox vs Rockies Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CHW: (-235) | COL: (+194)
• Spread: CHW: -1.5 (-110) | COL: +1.5 (-110)
• Total: 8.5 -- Over: (+110) | Under: (-134)

White Sox vs Rockies Probable Starting Pitchers

Probable Pitchers: Davis Martin (White Sox) - 9-7, 3.84 ERA vs José Quintana (Rockies) - 2-3, 5.40 ERA

The White Sox will look to Davis Martin (9-7) against the Rockies and Jose Quintana (2-3). Martin's team is 14-13-0 against the spread this season in his starts. Martin's team has a record of 4-4 this season when he starts and they are the favorite on the moneyline. When Quintana starts, the Rockies are 6-4-0 against the spread. The Rockies have been the underdog on the moneyline in 10 of Quintana's starts this season, and they went 5-5 in those matchups.

White Sox vs Rockies Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: White Sox win (69.5%)

White Sox vs Rockies Moneyline

• The White Sox vs Rockies moneyline has Chicago as a -235 favorite, while Colorado is a +194 underdog on the road.

White Sox vs Rockies Spread

• The White Sox are favored by 1.5 runs at home against the Rockies. The White Sox are -110 to cover the spread, while the Rockies are -110.

White Sox vs Rockies Over/Under

• The White Sox-Rockies contest on Sept. 26 has been given an over/under of 8.5 runs. The over is set at +110 and the under at -134.

Bet on Chicago White Sox vs. Colorado Rockies on FanDuel today!

White Sox vs Rockies Betting Trends

• The White Sox have been favorites in 44 games this season and have come away with the win 25 times (56.8%) in those contests.
• Chicago has played as a favorite of -235 or more just one time this year and came away with a win in that game.
• The White Sox and their opponents have gone over the total this season in 88 of their 157 opportunities.
• The White Sox are 89-68-0 against the spread in their 157 games that had a posted line this season.
• The Rockies have been the underdog on the moneyline 153 total times this season. They've gone 54-99 in those games.
• When playing as a moneyline underdog with odds of +194 or longer, Colorado has a 6-19 record (winning just 24% of its games).
• The Rockies have played in 157 games with a set over/under, and have combined with opponents to go over the total 76 times (76-78-3).
• The Rockies are 81-76-0 against the spread this season.

White Sox Player Leaders

• Miguel Vargas has 31 doubles, a triple, 33 home runs and 98 walks while batting .251. He has an on-base percentage of .361 and a slugging percentage of .476.
• Among the qualifying batters in MLB, his batting average ranks 75th, his on-base percentage ranks 28th, and he is 29th in slugging.
• Chase Meidroth has an OPS of .763, fueled by an OBP of .350 and a team-best slugging percentage of .413 this season. He's batting .275.
• Among qualified hitters, he is 34th in batting average, 43rd in on-base percentage and 80th in slugging percentage.
• Meidroth enters this game looking to extend his four-game hit streak. In his last five games he is batting .444 with a double, two home runs, a walk and seven RBIs.
• Sam Antonacci leads Chicago with an OBP of .368 this season while batting .275 with 43 walks and 81 runs scored.
• Antonacci enters this game with four games in a row with at least one hit. During his last five outings he is hitting .400 with a double, a walk and three RBIs.
• Munetaka Murakami leads Chicago with 93 hits, batting .209 this season with 51 extra-base hits.
• Murakami takes a four-game hitting streak into this game. In his last five games he is hitting .353 with a double, three home runs, four walks and eight RBIs.

Rockies Player Leaders

• Jake McCarthy is hitting .293 with 30 doubles, 13 triples, 15 home runs and 29 walks. He's slugging .480 with an on-base percentage of .335.
• Including all the qualified hitters in the big leagues, his batting average is eighth, his on-base percentage ranks 59th, and he is 27th in slugging.
• TJ Rumfield paces his team with a .389 on-base percentage, and has a club-best .452 slugging percentage. He has a batting average of .299.
• Including all qualifying players, he is seventh in batting average, third in on-base percentage and 42nd in slugging percentage.
• Hunter Goodman has 125 hits, a team-best for the Rockies.
• Kyle Karros is batting .256 with 21 doubles, three triples, 13 home runs and 54 walks.

White Sox vs Rockies Head to Head

• 9/25/2026: 6-1 CHW (Favorite: White Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -250, Underdog Moneyline: +205)
• 7/6/2025: 6-4 COL (Favorite: White Sox, Spread: -1.5, Total: 11, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 7/5/2025: 10-3 CHW (Favorite: Rockies, Spread: -1.5, Total: 11, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 7/4/2025: 3-2 CHW (Favorite: White Sox, Spread: -1.5, Total: 11, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 6/30/2024: 5-4 COL (Favorite: White Sox, Spread: -1.5, Total: 7, Favorite Moneyline: -230, Underdog Moneyline: +190)
• 6/29/2024: 11-3 CHW (Favorite: White Sox, Spread: -1.5, Total: 9, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 8/20/2023: 10-5 CHW (Favorite: White Sox, Spread: -1.5, Total: 11.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 8/19/2023: 11-5 COL (Favorite: White Sox, Spread: -1.5, Total: 11.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 8/18/2023: 14-1 COL (Favorite: Rockies, Spread: -1.5, Total: 12, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 9/14/2022: 3-0 COL (Favorite: White Sox, Spread: -1.5, Total: 7.5, Favorite Moneyline: -275, Underdog Moneyline: +225)

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