Week 7 NFL Odds: Spreads, Moneylines, and Totals for Every Game

Six teams are on bye this week, but that still leaves plenty of NFL action on the Week 7 NFL schedule.

Here are the NFL betting odds for each game in Week 7.

Browns at Colts Week 7 Odds

• Spread: Browns (-3)
• Cleveland Browns Moneyline: -176
• Indianapolis Colts Moneyline: +148
• Total: 40.5

Colts rookie quarterback Anthony Richardson is out for the season due to a shoulder injury, which means Gardner Minshew will take over for the 3-3 Colts.

Minshew has played well enough (-0.02 opponent-adjusted EPA per drop back but with a sub-par 41.8% passing success rate). The team will need to rely on the backfield tandem of Zack Moss and Jonathan Taylor, who continued to split work in Week 6.

The Browns scored an upset win over the 49ers in Week 6 while starting P.J. Walker at quarterback. Walker threw for 192 yards and 2 interceptions with some bad overall efficiency.

Deshaun Watson could return in Week 7. He practiced in full on Friday.

Commanders at Giants Week 7 Odds

• Spread: Commanders (-2.5)
• Washington Commanders Moneyline: -146
• New York Giants Moneyline: +124
• Total: 37.5

This is a big road game for the Commanders, who picked up a 24-16 win over the Falcons in Week 6. Washington is now 3-3 and can't afford many more early-season losses if they want to try to keep pace in the NFC East -- and the wild card conversation.

The Giants pushed the Bills to the brink in Week 6 but ultimately came up short, losing 14-9 and falling to 1-5 on the season.

Quarterback Tyrod Taylor threw 36 times for 200 yards in a spot start while Daniel Jones was out.

Both Daniel Jones and Saquon Barkley were limited in practice on Friday.

Falcons at Buccaneers Week 7 Odds

• Spread: Buccaneers (-2.5)
• Atlanta Falcons Moneyline: +120
• Tampa Bay Buccaneers Moneyline: -142
• Total: 37.5

We've got an NFC South matchup between three-win teams in Tampa Bay this week with both squads coming off of losses in Week 6.

The Buccaneers mustered just 6 points against the Lions last week in a return from a bye.

The Falcons fell to the Commanders after a 307-yard, 2-touchdown, 3-interception game from Desmond Ridder.

Notably, rookie sensation Bijan Robinson is ceding work to Tyler Allgeier, both of whom had 13 carries in Week 6 (with Robinson taking the receiving work).

Bills at Patriots Week 7 Odds

• Spread: Bills (-8.5)
• Buffalo Bills Moneyline: -460
• New England Patriots Moneyline: +360
• Total: 40.5

The Patriots were able to put up 17 points in Week 6 but couldn't avoid a third straight loss.

Their quarterback room is full of questions, and Mac Jones has one of the worst EPA per drop back (-0.31) and success rate (40.8%) numbers across all starters.

The Bills' status as 8.5-point favorites makes sense even after a down game in Week 6 against the Giants.

Josh Allen has a crisp 0.19 EPA per drop back and a 55.6% success rate.

Raiders at Bears Week 7 Odds

• Spread: Raiders (-2.5)
• Las Vegas Raiders Moneyline: -154
• Chicago Bears Moneyline: +130
• Total: 37.5

The Las Vegas Raiders are favored in Week 7, so the expectation is that they are going to stretch their win streak to three games and get to 4-3 on the year.

Notably, only one three-win team (Washington at -43) has a worse point differential than the Raiders (-31).

Brian Hoyer will start at quarterback in place of Jimmy Garoppolo.

Chicago lost quarterback Justin Fields to a hand injury in Week 6. X-rays came back negative. He is listed as out.

Tyson Bagent is in place to draw the starting nod. A costly turnover ruined his EPA numbers, but he had a 53.3% success rate on 15 drop backs in relief in Week 6.

Lions at Ravens Week 7 Odds

• Spread: Ravens (-3)
• Detroit Lions Moneyline: +128
• Baltimore Ravens Moneyline: -152
• Total: 43.5

Two division leaders square up in Baltimore this week with a respectable three-point spread in favor of Baltimore.

The 5-1 Lions have won four straight games but lost RB David Montgomery in Week 6 to a rib injury. This could pave the way for a Jahmyr Gibbs breakout.

Gibbs was full in practice on Friday, while Montgomery is listed as out and Craig Reynolds was limited (and remains questionable).

Baltimore opted not to take a bye after a week in London and now host a feisty Lions team.

Steelers at Rams Week 7 Odds

• Spread: Rams (-3)
• Pittsburgh Steelers Moneyline: +148
• Los Angeles Rams Moneyline: -176
• Total: 43.5

Another tight early-week spread is found in Los Angeles at SoFi Stadium.

The Steelers are coming off of a bye to head to the west coast. Hopefully for Pittsburgh, quarterback Kenny Pickett can improve his play out of the bye. His 35.3% passing success rate is a league-low rate among starting quarterbacks.

TE Pat Freiermuth is out, but WR Diontae Johnson returned to a full practice this week.

The Rams, though, will be without breakout RB Kyren Williams after an ankle injury in Week 6.

Cardinals at Seahawks Week 7 Odds

• Spread: Seahawks (-7.5)
• Arizona Cardinals Moneyline: +315
• Seattle Seahawks Moneyline: -400
• Total: 44.5

Barring a tie, one of these NFC West teams will be snapping (or preventing) a losing streak.

The Cardinals lost three straight games and are now sizable road underdogs against Seattle. The team split the backfield work between Emari Demercado and Keaontay Ingram while James Conner was out in Week 6.

As for the Seahawks, they fell short in their return from bye and lost 17-13 to the Bengals on the road.

Chargers at Chiefs Week 7 Odds

• Spread: Chiefs (-5.5)
• Los Angeles Chargers Moneyline: +194
• Kansas City Chiefs Moneyline: -230
• Total: 47.5

Offensive expectations are high in Kansas City this week between the Chiefs and Chargers.

Both Justin Herbert (266.6) and Patrick Mahomes (265.5) are top-seven in passing yards per game while maintaining elite EPA per drop back numbers.

A big difference could be pass defense, though. The Chiefs are top-five in EPA per drop back allowed, but the Chargers are bottom-five.

Packers at Broncos Week 7 Odds

• Spread: Packers (-1.5)
• Green Bay Packers Moneyline: -116
• Denver Broncos Moneyline: -102
• Total: 45

One of just two teams on bye in Week 6, the Packers hold early-week road-favorite status against the Broncos, who have lost two straight games and have a -71 point differential on the year.

Packers QB Jordan Love posted elite efficiency numbers through two games but has since fell off: over his past three starts, he is averaging 6.2 yards per attempt and -0.30 EPA per drop back.

Russell Wilson and the Broncos got stifled on Thursday night in Week 6. Wilson threw for just 95 yards on 22 attempts. He now has averaged -0.16 EPA per drop back for the season.

Dolphins at Eagles Week 7 Odds

• Spread: Eagles (-2.5)
• Miami Dolphins Moneyline: +126
• Philadelphia Eagles Moneyline: -148
• Total: 51.5

A primetime-worthy game is set for Sunday Night Football.

The 5-1 Eagles host the 5-1 Dolphins.

Unsurprisingly, Tua Tagovailoa leads the NFL in EPA per drop back (0.32) while averaging 312.7 yards per game and 9.5 yards per attempt.

Jalen Hurts' efficiency is markedly worse (-0.03 EPA per drop back), but he is averaging 42.2 yards per game on the ground.

Pass-catchers DeVonta Smith and Dallas Goedert were limited in practice on Friday.

49ers at Vikings Week 7 Odds

• Spread: 49ers (-7)
• San Francisco 49ers Moneyline: -330
• Minnesota Vikings Moneyline: +265
• Total: 44

The Vikings will need to hold serve at home without superstar receiver Justin Jefferson. They won 19-13 over the Bears on the road without Jefferson in Week 6.

This matchup is a bit different.

The 49ers are second in EPA per drop back allowed to QBs, and Kirk Cousins' efficiency in Week 6 was pretty horrendous: -0.30 EPA per drop back and a 36.4% passing success rate.

San Francisco is dealing with injuries to Christian McCaffrey and Deebo Samuel, too, but they're the clear favorites -- even on the road.

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