USC vs Washington Prediction, Odds, Picks, Best Bets for Week 5 2026

NCAA football action on Saturday includes the USC Trojans taking on the Washington Huskies.

Before you make your wager on FanDuel Sportsbook, we've got you covered with all the latest NCAA football betting insights.

USC vs Washington Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: USC: (-330) | Washington: (+260)
• Spread: USC: -9.5 (-104) | Washington: +9.5 (-118)
• Total: 58.5 -- Over: (-105) | Under: (-115)

USC vs Washington Betting Trends

• USC hasn won once against the spread this year.
• USC owns one win ATS (1-3) as a 9.5-point favorite or greater this year.
• There have been four USC games (of five) that went over the total this season.
• Washington is winless against the spread this season.
• Two Washington games (of four) have hit the over this year.

USC vs Washington Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Trojans win (79.8%)

USC vs Washington Point Spread

USC is favored by 9.5 points over Washington. USC is -104 to cover the spread, with Washington being -118.

USC vs Washington Over/Under

The over/under for USC-Washington on Oct. 3 is 58.5. The over is -105, and the under is -115.

USC vs Washington Moneyline

USC is a -330 favorite on the moneyline, while Washington is a +260 underdog.

USC vs. Washington Points Insights

USC vs. Washington Game Info

• Game day: Saturday, October 3, 2026
• Game time: 7:30 p.m. ET
• TV channel: NBC
• Location: Los Angeles, California
• Stadium: Los Angeles Memorial Coliseum

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Check out even more in-depth USC vs. Washington analysis on FanDuel Research.