Twins vs Royals Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 6

Odds updated as of 5:15 a.m.

The Minnesota Twins will face the Kansas City Royals in MLB action on Saturday.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the vital information about this matchup.

Twins vs Royals Game Info

• Minnesota Twins (62-79) vs. Kansas City Royals (72-69)
• Date: Saturday, September 6, 2025
• Time: 7:15 p.m. ET
• Venue: Kauffman Stadium -- Kansas City, Missouri
• Coverage: FOX

Twins vs Royals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: MIN: (-116) | KC: (-102)
• Spread: MIN: -1.5 (+140) | KC: +1.5 (-170)
• Total: 8.5 -- Over: (-100) | Under: (-122)

Twins vs Royals Probable Starting Pitchers

Probable Pitchers: Joe Ryan (Twins) - 13-7, 3.08 ERA vs Stephen Kolek (Royals) - 4-5, 3.99 ERA

The probable pitchers are Joe Ryan (13-7) for the Twins and Stephen Kolek (4-5) for the Royals. Ryan and his team have a record of 12-13-0 against the spread when he starts. Ryan's team is 11-9 this season when he starts and they are the moneyline favorite. The Royals have gone 10-5-0 ATS in Kolek's 15 starts that had a set spread. The Royals have been the moneyline underdog in eight of Kolek's starts this season, and they went 3-5 in those games.

Twins vs Royals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Twins win (54.8%)

Twins vs Royals Moneyline

• Looking at the moneyline for Royals-Twins, Kansas City is the underdog at -102, and Minnesota is -116 playing on the road.

Twins vs Royals Spread

• The Twins are at the Royals and are favored by 1.5 runs on the spread. The Twins are +140 to cover the runline, with the Royals being -170.

Twins vs Royals Over/Under

• Twins versus Royals, on Sept. 6, has an over/under of 8.5, with the over being -100 and the under -122.

Bet on Minnesota Twins vs. Kansas City Royals on FanDuel today!

Twins vs Royals Betting Trends

• The Twins have come away with 39 wins in the 81 contests they have been listed as the favorites in this season.
• This season Minnesota has been victorious 34 times in 68 chances when named as a favorite of at least -116 on the moneyline.
• The Twins and their opponents have hit the over in 64 of their 136 games with a total set by oddsmakers this season.
• The Twins are 66-70-0 against the spread in their 136 games with a line set by sportsbooks this season.
• The Royals have been the underdog on the moneyline 78 total times this season. They've finished 36-42 in those games.
• Kansas City has gone 27-40 when playing as a moneyline underdog with odds of -102 or longer (40.3%).
• The Royals have had an over/under set by bookmakers 139 times, and have combined with opponents to go over the total in 58 of those games (58-79-2).
• The Royals have put together a 69-70-0 record against the spread this season.

Twins Player Leaders

• Byron Buxton leads Minnesota with 112 hits, batting .271 this season with 53 extra-base hits. He has an on-base percentage of .330 and a slugging percentage of .553.
• Among the qualified hitters in MLB, his batting average ranks 39th, his on-base percentage ranks 76th, and he is sixth in slugging.
• Trevor Larnach has an OPS of .743, fueled by an OBP of .329 and a team-best slugging percentage of .413 this season. He's batting .258.
• Among all qualified hitters, he is 81st in batting average, 80th in on-base percentage and 93rd in slugging percentage.
• Larnach heads into this game looking to extend his seven-game hit streak. In his last 10 games he is hitting .432 with two doubles, three walks and five RBIs.
• Brooks Lee is batting .243 with a .381 slugging percentage and 57 RBI this year.
• Ryan Jeffers leads Minnesota in OBP (.353) this season, fueled by 101 hits.

Royals Player Leaders

• Bobby Witt Jr. has 160 hits with a .503 slugging percentage, both team-best numbers for the Royals. He's batting .294 and with an on-base percentage of .352.
• Including all the qualifying hitters in the big leagues, his batting average places him 11th, his on-base percentage ranks 39th, and he is 17th in slugging.
• Maikel Garcia has a .357 OBP to lead his team. He has a batting average of .294 while slugging .472.
• He ranks 11th in batting average, 26th in on-base percentage and 38th in slugging percentage in MLB.
• Vinnie Pasquantino is hitting .260 with 23 doubles, a triple, 29 home runs and 43 walks.
• Salvador Perez is batting .238 with 33 doubles, 24 home runs and 23 walks.

Twins vs Royals Head to Head

• 9/5/2025: 2-1 KC (Favorite: Royals, Spread: -1.5, Total: 8, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 8/10/2025: 5-3 MIN (Favorite: Twins, Spread: -1.5, Total: 9.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 8/9/2025: 2-0 KC (Favorite: Royals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 8/8/2025: 9-4 MIN (Favorite: Twins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 5/25/2025: 2-1 KC (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 5/24/2025: 5-4 MIN (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 5/23/2025: 3-1 MIN (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -190, Underdog Moneyline: +160)
• 4/10/2025: 3-2 KC (Favorite: Royals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 4/9/2025: 4-0 MIN (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 4/8/2025: 2-1 KC (Favorite: Royals, Spread: -1.5, Total: 7.5, Favorite Moneyline: -124, Underdog Moneyline: +106)

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