Twins vs Nationals Prediction, Odds, Moneyline, Spread & Over/Under for May 5

Odds updated as of 2:11 p.m.

The Minnesota Twins are among the MLB teams playing on Tuesday, versus the Washington Nationals.

We've got you covered, in terms of the most important information regarding this game before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Twins vs Nationals Game Info

• Minnesota Twins (15-20) vs. Washington Nationals (16-19)
• Date: Tuesday, May 5, 2026
• Time: 6:45 p.m. ET
• Venue: Nationals Park -- Washington, District of Columbia
• Coverage: Nationals.TV and Twins.TV

Twins vs Nationals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: MIN: (-112) | WSH: (-104)
• Spread: MIN: -1.5 (+130) | WSH: +1.5 (-156)
• Total: 9.5 -- Over: (-104) | Under: (-118)

Twins vs Nationals Probable Starting Pitchers

Probable Pitchers: Taj Bradley (Twins) - 3-1, 2.85 ERA vs Cade Cavalli (Nationals) - 1-1, 3.82 ERA

The probable starters are Taj Bradley (3-1) for the Twins and Cade Cavalli (1-1) for the Nationals. Bradley's team is 4-3-0 against the spread in his starts this season. Bradley's team lost his only start as a favorite this season. The Nationals are 5-2-0 against the spread when Cavalli starts. The Nationals are 2-4 in Cavalli's six starts this season that they were the moneyline underdog.

Twins vs Nationals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Twins win (54.9%)

Twins vs Nationals Moneyline

• The Twins vs Nationals moneyline has Minnesota as a -112 favorite, while Washington is a -104 underdog at home.

Twins vs Nationals Spread

• The Nationals are +1.5 on the spread (-156 to cover), and Minnesota is +130 to cover the runline.

Twins vs Nationals Over/Under

• An over/under of 9.5 has been set for Twins-Nationals on May 5, with the over being -104 and the under -118.

Bet on Minnesota Twins vs. Washington Nationals on FanDuel today!

Twins vs Nationals Betting Trends

• The Twins have been chosen as favorites in nine games this year and have walked away with the win three times (33.3%) in those games.
• This year Minnesota has won two of seven games when listed as at least -112 on the moneyline.
• The Twins' games have gone over the total in 21 of their 35 opportunities.
• The Twins have posted a record of 17-18-0 against the spread this season.
• The Nationals have been the underdog on the moneyline 34 total times this season. They've finished 16-18 in those games.
• Washington is 16-17 (winning 48.5% of its games) when it has played as a moneyline underdog of -104 or longer.
• The Nationals have played in 35 games with an over/under set, and have combined with their opponents to go over the total 21 times (21-12-2).
• The Nationals have collected a 19-16-0 record against the spread this season (covering 54.3% of the time).

Twins Player Leaders

• Byron Buxton has 34 hits and an OBP of .313 to go with a slugging percentage of .530. All three of those stats lead Minnesota hitters this season. He has a .254 batting average, as well.
• Among qualifying hitters in baseball, he is 82nd in batting average, 119th in on-base percentage, and 22nd in slugging.
• Ryan Jeffers is batting .287 with two doubles, a triple, four home runs and 15 walks, while slugging .471 with an on-base percentage of .394.
• Josh Bell is batting .218 with a .336 slugging percentage and 17 RBI this year.
• Brooks Lee is batting .255 with a .311 OBP and 18 RBI for Minnesota this season.
• Lee has safely hit in three games in a row. During his last five outings he is batting .316 with three RBIs.

Nationals Player Leaders

• C.J. Abrams has accumulated a team-best OBP (.406) and slugging percentage (.534), and paces the Nationals in hits (35, while batting .297).
• Including all qualifying hitters, he ranks 30th in batting average, while his on-base percentage ranks 13th and he is 19th in slugging.
• James Wood is batting .231 with seven doubles, 10 home runs and 31 walks. He's slugging .507 with an on-base percentage of .383.
• He is currently 116th in batting average, 24th in on-base percentage and 27th in slugging percentage among all qualifying hitters.
• Daylen Lile is hitting .246 with eight doubles, three home runs and 13 walks.
• Nasim Nunez is batting .222 with a double and 14 walks.

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!