Twins vs Guardians Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 16

Odds updated as of 6:12 p.m.

The Minnesota Twins will take on the Cleveland Guardians in MLB action on Monday.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the most important information regarding this game.

Twins vs Guardians Game Info

• Minnesota Twins (79-70) vs. Cleveland Guardians (86-64)
• Date: Monday, September 16, 2024
• Time: 6:40 p.m. ET
• Venue: Progressive Field -- Cleveland, Ohio
• Coverage: BSGL

Twins vs Guardians Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: MIN: (-118) | CLE: (-100)
• Spread: MIN: -1.5 (+136) | CLE: +1.5 (-164)
• Total: 7.5 -- Over: (-102) | Under: (-120)

Twins vs Guardians Probable Starting Pitchers

Probable Pitchers: Pablo Lopez (Twins) - 15-8, 3.88 ERA vs Matthew Boyd (Guardians) - 2-1, 2.18 ERA

The Twins will give the ball to Pablo Lopez (15-8, 3.88 ERA), who is eyeing win No. 16 on the season, and the Guardians will turn to Matthew Boyd (2-1, 2.18 ERA). Lopez's team is 14-14-0 against the spread in his starts this season. When Lopez starts a game and his team is the favorite on the moneyline, they have a record of 16-7. The Guardians have a 4-2-0 record against the spread in Boyd's starts. The Guardians were the moneyline underdog for two Boyd starts this season -- they won both.

Twins vs Guardians Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Twins win (50.3%)

Twins vs Guardians Moneyline

• The moneyline numbers for Twins vs. Guardians reveal Minnesota as the favorite (-118) and Cleveland as the underdog (-100) despite being the home team.

Twins vs Guardians Spread

• The Twins are 1.5-run road favorites on the runline against the Guardians. The Twins are +136 to cover, and the Guardians are -164.

Twins vs Guardians Over/Under

• Twins versus Guardians, on Sept. 16, has an over/under of 7.5, with the over being -102 and the under -120.

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Twins vs Guardians Betting Trends

• The Twins have been favorites in 99 games this season and have come away with the win 60 times (60.6%) in those contests.
• This year Minnesota has won 56 of 91 games when listed as at least -118 on the moneyline.
• Contests with the Twins have gone over the total set by oddsmakers in 73 of 145 chances this season.
• The Twins have an against the spread record of 64-81-0 in 145 games with a line this season.
• The Guardians have won 43.6% of the games this season they were the moneyline underdog (24-31).
• Cleveland has a 17-25 record (winning 40.5% of its games) when it has played as a moneyline underdog of -100 or longer.
• The Guardians have played in 148 games with a set over/under, and have combined with their opponents to go over the total 68 times (68-72-8).
• The Guardians have covered 52.7% of their games this season, going 78-70-0 ATS.

Twins Player Leaders

• Carlos Santana leads Minnesota in total hits (115) this season while batting .243 with 47 extra-base hits. He has an on-base percentage of .331 and a slugging percentage of .436.
• Among all qualified hitters in MLB, he ranks 96th in batting average, 52nd in on-base percentage, and 60th in slugging.
• Santana hopes to build on a five-game hitting streak in this matchup. In his last five games he is batting .444 with a double, two home runs, two walks and five RBI.
• Willi Castro leads the Twins with an OPS of .722. He has a slash line of .249/.334/.388 this season.
• He is 77th in batting average, 48th in on-base percentage and 107th in slugging in the major leagues.
• Castro enters this matchup looking to extend his four-game hit streak. In his last five games he is hitting .286 with a walk and three RBI.
• Ryan Jeffers has collected 88 base hits, an OBP of .308 and a slugging percentage of .449 this season.
• Jose Miranda has nine home runs, 49 RBI and a batting average of .292 this season.

Guardians Player Leaders

• Jose Ramirez has accumulated a team-best slugging percentage (.516) while leading the Guardians in hits (157). He's batting .272 and with an on-base percentage of .330.
• Including all qualifying hitters in the majors, he ranks 34th in batting average, 54th in on-base percentage and 13th in slugging percentage.
• Ramirez enters this game on an eight-game hitting streak. During his last 10 outings he is batting .256 with three doubles, a home run, five walks and an RBI.
• Josh Naylor is batting .245 with 25 doubles, 29 home runs and 55 walks. He's slugging .459 with an on-base percentage of .323.
• He is currently 90th in batting average, 73rd in on-base percentage and 38th in slugging percentage among all qualified hitters.
• Steven Kwan a has .364 on-base percentage to pace the Guardians.
• Andres Gimenez has 20 doubles, a triple, eight home runs and 25 walks while hitting .251.

Twins vs Guardians Head to Head

• 8/11/2024: 5-3 CLE (Favorite: Twins, Spread: -1.5, Total: 8, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 8/9/2024: 6-3 MIN (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 8/9/2024: 4-2 MIN (Favorite: Twins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 5/19/2024: 5-2 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 5/18/2024: 11-4 CLE (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 5/17/2024: 3-2 CLE (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 4/6/2024: 3-1 CLE (Favorite: Twins, Spread: -1.5, Total: 8, Favorite Moneyline: -180, Underdog Moneyline: +152)
• 4/4/2024: 4-2 CLE (Favorite: Twins, Spread: -1.5, Total: 7, Favorite Moneyline: -164, Underdog Moneyline: +138)
• 9/6/2023: 2-1 CLE (Favorite: Twins, Spread: -1.5, Total: 8, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 9/5/2023: 8-3 MIN (Favorite: Twins, Spread: -1.5, Total: 8, Favorite Moneyline: -120, Underdog Moneyline: +102)

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