Twins vs Guardians Prediction, Odds, Moneyline, Spread & Over/Under for May 19

Odds updated as of 5:14 a.m.

The MLB's Monday schedule includes the Minnesota Twins taking on the Cleveland Guardians.

Here's what you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Twins vs Guardians Game Info

• Minnesota Twins (26-21) vs. Cleveland Guardians (25-21)
• Date: Monday, May 19, 2025
• Time: 7:40 p.m. ET
• Venue: Target Field -- Minneapolis, Minnesota
• Coverage: MNNT and CLEG

Twins vs Guardians Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: MIN: (-142) | CLE: (+120)
• Spread: MIN: -1.5 (+158) | CLE: +1.5 (-192)
• Total: 7.5 -- Over: (-110) | Under: (-110)

Twins vs Guardians Probable Starting Pitchers

Probable Pitchers: Bailey Ober (Twins) - 4-1, 3.72 ERA vs Logan Allen (Guardians) - 2-2, 3.70 ERA

The Twins will give the nod to Bailey Ober (4-1) against the Guardians and Logan Allen (2-2). Ober's team is 6-3-0 against the spread in his starts this season. Ober's team has won 75% of his starts when they are favored on the moneyline (3-1). The Guardians have a 3-5-0 record against the spread in Allen's starts. The Guardians have a 2-3 record in Allen's five starts this season when they were the underdog on the moneyline.

Twins vs Guardians Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Twins win (62.8%)

Twins vs Guardians Moneyline

• The moneyline numbers for Twins vs. Guardians reveal Minnesota as the favorite (-142) and Cleveland as the underdog (+120) on the road.

Twins vs Guardians Spread

• The Guardians are at the Twins, and are +1.5 on the runline. The Guardians are +158 to cover the spread, and the Twins are -192.

Twins vs Guardians Over/Under

• Twins versus Guardians on May 19 has an over/under of 7.5 runs, with the odds on the over -110 and the under set at -110.

Bet on Minnesota Twins vs. Cleveland Guardians on FanDuel today!

Twins vs Guardians Betting Trends

• The Twins have been victorious in 17, or 58.6%, of the 29 contests they have been chosen as favorites in this season.
• This season Minnesota has been victorious nine times in 12 chances when named as a favorite of at least -142 on the moneyline.
• The Twins and their opponents have gone over in 16 of their 46 games with a total set by sportsbooks this season.
• The Twins are 26-20-0 against the spread in their 46 games with a line set by sportsbooks this season.
• The Guardians have won 46.2% of the games this season they were the underdog on the moneyline (12-14).
• In games it has played as a moneyline underdog with odds of +120 or longer, Cleveland has a record of 4-5 (44.4%).
• In the 45 games oddsmakers have set an over/under for the Guardians, they have combined with opponents to go over the total 22 times (22-21-2).
• The Guardians have collected a 20-25-0 record against the spread this season (covering 44.4% of the time).

Twins Player Leaders

• Trevor Larnach leads Minnesota OPS (.749) this season. He has a .250 batting average, an on-base percentage of .330, and a slugging percentage of .419.
• Among qualified hitters in baseball, his batting average ranks 88th, his on-base percentage ranks 81st, and he is 82nd in slugging.
• Larnach has picked up at least one hit in three games in a row. In his last five games he is hitting .238 with a double, a triple, a home run, two walks and two RBIs.
• Ty France is hitting .253 with eight doubles, three home runs and 10 walks. He's slugging .355 with an on-base percentage of .317.
• He ranks 83rd in batting average, 101st in on-base percentage and 133rd in slugging in the major leagues.
• Harrison Bader has collected 33 base hits, an OBP of .366 and a slugging percentage of .432 this season.
• Ryan Jeffers has three home runs, 17 RBI and a batting average of .268 this season.
• Jeffers has safely hit in three straight games. In his last five games he is hitting .364 with a double, a home run, a walk and an RBI.

Guardians Player Leaders

• Jose Ramirez has collected 48 hits, a team-best for the Guardians. He's batting .296 and slugging .519 with an on-base percentage of .359.
• He ranks 25th in batting average, 45th in on-base percentage and 19th in slugging percentage among all qualifying hitters in MLB.
• Ramirez brings a 12-game hitting streak into this game. During his last 10 games he is hitting .378 with two doubles, four home runs, four walks and seven RBIs.
• Steven Kwan's .374 on-base percentage and .428 slugging percentage both pace his team. He has a batting average of .311.
• He ranks 11th in batting average, 28th in on-base percentage and 74th in slugging percentage in MLB.
• Kyle Manzardo is batting .221 with four doubles, two triples, 10 home runs and 18 walks.
• Carlos Santana is hitting .222 with three doubles, four home runs and 23 walks.

Twins vs Guardians Head to Head

• 5/1/2025: 4-3 CLE (Favorite: Twins, Spread: -1.5, Total: 9, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 4/30/2025: 4-2 CLE (Favorite: Twins, Spread: -1.5, Total: 7, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 4/28/2025: 11-1 MIN (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 9/19/2024: 3-2 CLE (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 9/18/2024: 5-4 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 9/17/2024: 4-1 MIN (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 9/16/2024: 4-3 CLE (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 8/11/2024: 5-3 CLE (Favorite: Twins, Spread: -1.5, Total: 8, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 8/9/2024: 6-3 MIN (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 8/9/2024: 4-2 MIN (Favorite: Twins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -162, Underdog Moneyline: +136)

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